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Microbiology- Gram postive bacilli
Aerobic gram pos. bacilli
46
Biology
Undergraduate 4
10/20/2009

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Term
What gram positive bacilli produce spores?
Definition
Bacillus spp.
Term
What are the four genera of partially acid-fast branching, filamentous, gram positive bacilli?
Definition
Nocardia, Rhodococcus, Gordona, Tsukamurella
Term
Is Streptomyces acid-fast or non-acid fast?
Definition
non acid-fast
Term
What are the four species of Corynebacterium?
Definition
C. diphtheriae, C. ulcerans, C. pseudotuberculosis, C. jeikeium
Term
The term 'diphtheroids' refers to what genera?
Definition
Corynebacterium
Term
What Corynebacterium species is sensitive to penicillin?
Definition
C. diphtheriae
Term
What genus has a characteristic club-shape with palisading of organisms?
Definition
Corynebacterium
Term
Are Corynebacterium motile or non-motile?
Definition
non-motile
Term
Do Corynebacterium sp. form spores?
Definition
No.
Term
What kind of granules are present in Corynebacterium that cause them to stain unevenly?
Definition
metachromatic granules
Term
What four types of media are used for Corynebacterium?
Definition
Cysteine-tellurite agar, Loefflers, Tinsdale medium, Blood agar
Term
What three species produce the exotoxin Diphtheria toxin?
Definition
Corynebacterium diphtheriae; C. ulcerans; C. pseudotuberculosis
Term
Strains of what two species produce dermonecrotic toxin?
Definition
Corynebacterium ulcerans and C. pseudotuberculosis
Term
What toxin is a sphingomyelinase that increases vascular permeability?
Definition
Dermonecrotic toxin
Term
What is the incubation period of Corynebacterium diphtheriae?
Definition
2-4 days
Term
What toxin causes the pseudomembrane to form in Corynebacterium diphtheriae infections?
Definition
Diphtheria toxin
Term
The pseudomembrane produced in diphtheria is composed of what 4 components?
Definition
fibrin, leukocytes, cellular debris, bacteria
Term
Cervical adenitis or 'bullneck' appearance is characteristic of what disease?
Definition
diphtheria
Term
What is the natural habitat of Corynebacterium diphtheriae?
Definition
normal flora of skin and oral cavity
Term
What 3 routes of transmission are associated with Corynebacterium diphtheriae?
Definition
droplet aerosols, direct contact, fomites
Term
The Schick test is used to determine immunity to what organism?
Definition
Corynebacterium diphtheriae
Term
What three organisms produce a brown to black halo on Tinsdale medium?
Definition
Corynebacterium diphtheriae, C. ulcerans, C. pseudotuberculosis
Term
What Corynebacterium species is resistant to all antibiotics except vancomycin?
Definition
C. jeikeium
Term
What is the name of the immunodiffusion test for diphtheria toxin production?
Definition
Elek test
Term
What kind of testing must be done to confirm the patient has diphtheria?
Definition
Toxigenic testing
Term
What Corynebacterium species is similar to C. diphtheriae but milder, with lower levels of toxin production?
Definition
C. ulcerans
Term
What species of Corynebacterium causes nosocomial infections in immunocompromised and bacteremia associated with prosthetic devices?
Definition
C. jeikeium
Term
What is the natural habitat of Corynebacterium jeikeium?
Definition
normal flora of skin and oral cavity
Term
Is Listeria monocytogenes motile?
Definition
yes- tumbling motility
Term
Is Listeria monocytogenes hemolytic?
Definition
beta-hemolytic on blood agar
Term
Is Listeria monocytogenes more motile at room temperature or body temperature?
Definition
room temperature
Term
Describe the oxygen requirements of Listeria monocytogenes?
Definition
Facultative anaerobe
Term
What kind of motility does Listeria monocytogenes show in agar?
Definition
umbrella
Term
What organism causes Granulomatosis infantiseptica?
Definition
Listeria monocytogenes
Term
What organism is the most common cause of meningitis in renal transplant patients?
Definition
Listeria monocytogenes
Term
What two groups of people are most likely to die of Listeria monocytogenes infection?
Definition
under 4 weeks old and over 50
Term
What is the natural habitat of Listeria monocytogenes?
Definition
Zoonotic; soil; water; vegatation; humans- 1-5%
Term
What is the drug of choice for treatment of Listeria monocytogenes infection?
Definition
penicillin
Term
What test can be used to differentiate between Listeria and Strep?
Definition
Catalase- Listeria is positive; Strep is negative
Term
Is Erysipelothrix rhusiopathiae hemolytic?
Definition
alpha hemolytic
Term
What part of the body is involved in Erysipelas?
Definition
fingers and hands
Term
What animal is the main reservoir of Erysipelothrix?
Definition
Pigs
Term
Who is at risk for Erysipelothrix infection?
Definition
butchers, meat processors, farmers, poultry workers, fish handlers, veterinarians
Term
What aerobic condition does Erysipelothrix grow best under?
Definition
microaerophilic
Term
Which gram positive bacilli produces H2S?
Definition
Erysipelothrix
Term
Is Corynebacterium catalase positive or negative?
Definition
positive
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