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Microbiology
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167
Biology
Undergraduate 2
05/17/2009

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Term
These receptors bind to free agents often found in bone marrow
Definition
B Cell Receptors
Term
These receptors bind to processed antigens often found in the thymus
Definition
T Cell Receptors
Term
This system is located on all cells except RBC and is used for self recognition
Definition
Major Histocompatability Complex (MHC)
Term
Ag
Definition
antigen
Term
Ig
Definition
Immunoglobin
Term
Large glycoproteins that contain specific receptors to B Cells with 4 polypeptide chains (2 heavy and 2 light)in a Yshape and antigen binding sites
Definition
Immunoglbin
Term
These cell receptors are formed by genetic recombination
Definition
T cell receptors
Term
Substance that provokes immune responses in specific lymphocytes
Definition
antigen
Term
patent T cell simulator producing an overwhelming response
Definition
super antigen
Term
molecule on self tissues that tolerance is inadequate
Definition
auto antigens
Term
after the first exposure to antigen the immune system produces IgM and gradually increases in Ab titer.
Definition
primary response
Term
Ab
Definition
antibody
Term
after a second contact with the same antigen, the immune system produces a rapid and strong response due to memory cells
Definition
secondary response
Term
how proteins kill each other
Definition
antigen-antibody reaction
Term
recognition by T-cells and release of interleukins to begin immune system reaction
Definition
macrophage
Term
Cell used to assist T and B cells and to conduct an immune response
Definition
T helper cell
Term
cell used to destroy foreign cells by secreting perforins to lyse
Definition
cytotoxic cell
Term
allergies that show reactions hours or days after initial contact
Definition
delayed hypersensitivity
Term
cell used to limit number of T and B cells, and to turn off their actions
Definition
T supressor Cells
Term
misdirected expression of immune response
Definition
allergen
Term
abnormal response to antigen
Definition
auto immunity
Term
decreased immunity
Definition
immunodeficiency
Term
type 1 hypersensitivity causing chronic local allergy such as hay fever and asthma
Definition
atopy
Term
type one hypersensitivity that is systemic and often causes airway constriction and circulatory collapse
Definition
anaphalxis
Term
first dose of an allergen often with out S/S
Definition
sensitizing dose
Term
subsequent exposure to an allergen
Definition
provocative dose
Term
these cells degranulate when stimulated by allergen
Definition
mast cells and basophils
Term
profuse and fast acting stimulus effecting SM, eosinphils, and glands
Definition
histamine
Term
algal, fungal (yeast), and protozoan
Definition
3 types of eucaryotic cells
Term
found in animal cells, used for motility, feeding and filter
Definition
cilia
Term
outer boundary of polysaccharides used for protection, adherence, and signal reception
Definition
glycocalax
Term
this cell organelle holds the chromosomes
Definition
nucleus
Term
cell organelle where rRNA synthesis takes place
Definition
neculeolus
Term
this cell organelle stores lipids
Definition
smooth Er
Term
this cell organelle is where protein synthesis takes place
Definition
rough Er
Term
this cell organelle is used in protein transport
Definition
golgi apparatus
Term
this cell organelle protects the cell against living microbes and helps with intra-cellular digestion
Definition
lysosome
Term
this cell organelle found in plants that provides nutrients
Definition
chloroplast
Term
this cell organelle containing rRNA and protein and aid in protein synthesis
Definition
ribosome
Term
mass of hyphea
Definition
mycelium
Term
hypae
Definition
mold
Term
spores formed through budding
Definition
asexual reproduction
Term
spores formed through fusion of male and female strains
Definition
sexual reproduction
Term
these organisms live off dead plants and animal
Definition
saprobe
Term
these organisms live off other organizim
Definition
parasite
Term
motile feeding stage
Definition
trophozoite
Term
can enter resting/dormant stage when non-favorable feeding conditions
Definition
cyst
Term
sexual reproduction
Definition
conjugation
Term
flatworms and round worms that are commonly parasites to humans
Definition
helminths
Term
fully formed virus that is able to establish infection
Definition
viron
Term
spectrum of cells a virus can infect
Definition
host range
Term
virus induced damage to cells
Definition
cytopathic effect
Term
misfolded protein with no nucleic acid often causing neurodegenerative disease
Definition
prion
Term
depends on other viruses for replication
Definition
viroid
Term
form of penetration when entire virus is engulfed and closed in a vacule/vessicle
Definition
endocytosis
Term
form of penetration when the envelope merges directly with the membrane resulting in nucleocaspids entry into cytoplasm
Definition
fusion
Term
form of release when the nucleocaspid binds to the membrane which pinches off and the virus is gradually shed
Definition
budding
Term
form of release when a non envoloped and complex viruses released when the cell dies and ruptures
Definition
lysis
Term
lowest temperature that allows a microbes growth and metabolism
Definition
minimum temperature
Term
highest temperature that allows microbes growth and metabolism
Definition
maximum temperature
Term
temperature that promotes the fastest growth and metabolism
Definition
optimum temperature
Term
optimum temperature below 15 degrees C
Definition
psychrophiles
Term
optimum temperature 20-40 degrees C, usually human pathogens
Definition
mesophiles
Term
optimum temperature greater than 45 degrees C
Definition
thermophiles
Term
microbes that can grow in extreme acidic environments
Definition
obligate acidophiles
Term
microbes that grow at extreme basic/alkaline environments
Definition
alkainphiles
Term
utilize O2 and can detox it
Definition
aerobe
Term
cant grow without O2
Definition
obligate aerobe
Term
only requires a small amount of O2
Definition
macroaerophilic
Term
utilize O2 but can live without it
Definition
facultative anarobe
Term
done use O2 but can survive in its presence
Definition
aerotolerant anarobe
Term
organisms that grow in close nutritional relationships
Definition
symbiotic relationship
Term
in this symbiotic relationship both members benifit and they are dependent on one an other
Definition
mutualism
Term
in this symbiotic relationship the commensal member benifits, but the other member is unharmed
Definition
commensalism relationship
Term
in this symbiotic relationship the parasite is dependent and benifits while the host is harmed
Definition
parasitism
Term
This relationship contains free living organisms and are not required for survival
Definition
non-symbiotic relationship
Term
in this non-sybiotic relationship members cooperate and share nutrients but neither thrives
Definition
synergism
Term
in this non-sybiotic relationship some members anre inhibited/destroyed by others
Definition
anagonism
Term
in this stage of the growth curve the graph is flat with a period of adjustment and little growth
Definition
lag phase
Term
in this stage of the growth curve there is a period of maximum growth often due to continuous food and good environment
Definition
exponential growth phase
Term
in this stage of the growth curve cell growth equals cell death
Definition
stationary phase
Term
in this stage of the growth curve limiting factors intensify and cells die
Definition
death phase
Term
parent cell enlarges, duplicates chromosomes, form central transverse, and divides into two daughter cells
Definition
binary fission
Term
time required for binary fission to take place
Definition
generation/doubling time
Term
when the binary fission cycle increases the population by factor of 2
Definition
exponential
Term
sum of total genetic material of an organism
Definition
genome
Term
basic unit of DNA
Definition
nucleotide
Term
5 carbon sugar
Definition
deoxyribose
Term
AGTC
Definition
nitrogen base
Term
change in phenotype due to change of genotype
Definition
mutation
Term
type of mutation caused by a random change in DNA due to errors in replication that occurs without cause
Definition
spontaneous mutation
Term
type of mutation that results from exposure to known mutagens physical or chemical that interact with DNA in a disruptive manner
Definition
induced mutation
Term
when organism acquires and expresses genes originated from another organism
Definition
recombination
Term
transfer of plasmid/chromosomal fragments from donor cell to recipient cell via direct connection
Definition
conjugation
Term
chromosomal fragments from lysed cells are accepted by recipient cell
Definition
transformation
Term
bacteriophage serves as a carrier of DNA from donor cell to recipient
Definition
transduction
Term
this method of control destroys all microbes
Definition
sterilization
Term
this method of control destroys all vegetative pathogens
Definition
disinfection
Term
this method of control when disinfectant is applied to a bodily surface
Definition
antiseptic
Term
this method of control using a cleansing technique that mechanically removes microbes
Definition
sanatation
Term
this method of control decreases the number of microbes
Definition
degermation
Term
intermittent sterilization for a substance that cannot withstand autoclaving
Definition
tyrdallization
Term
heat is applied to kill potential agents of infection and spoilage without destroying food flavor and value
Definition
pasturiztion
Term
freeze drying/preservation
Definition
lyophilization
Term
type of radiation that causes deep penetration and breaks DNA
Definition
ionizing
Term
type of radiation that causes little penetration and must be directly exposed
Definition
non-ionizing
Term
this germicidal category denatures proteins, examples included chlorine and iodine
Definition
halogens
Term
common metabolic products of aerobic spore forming bacteria/fungi
Definition
antibiotics
Term
drugs that kill/inhibit microbial cells without simultaneously damaging the host tissue
Definition
selective toxicity
Term
drugs effective on small ranges of microbes, and target specific cell that is only in certain microbes
Definition
narrow spectrum
Term
drugs with great range of activity and targets cell components on most pathogens
Definition
broad spectrum
Term
drug competes with normal substrate for enzyme active site
Definition
competitive inhibition
Term
additive effect achieved by multiple drugs working together requiring low doses of each other
Definition
synergistic effect
Term
eventually the population will be resistant caused by selective pressure
Definition
natural selection
Term
microbes engaging in mutual/commensal association like that in the large intestine
Definition
normal flora
Term
condition with pathogenic microbes penetrating host defense, enters tissues, and multiplies
Definition
infection
Term
deviation from health, disruption of tissue or organ
Definition
disease
Term
pathogen capable of causing disease in healthy persons with normal immune defenses
Definition
true pathogens
Term
pathogens that cause disease when the host's defenses are compromised or with they grow in part of the body that is not natural to them. Ex: candida and psudemonas
Definition
oppurtunistic pathogens
Term
number of people effected by illness
Definition
morbidity
Term
disease that causes loss of pain perception and deep nodule infections on the face and extremities
Definition
leprosy
Term
bacteria, fungi, viruses, protazoa, worms, algea
Definition
microorganisms
Term
unicellular organisms without nucleus and are membrane bound
Definition
procaryote
Term
unicellular/multicellular organisms with nucleus and are membrane bound
Definition
eucaryote
Term
acellular parasitic particles composed of nucleic acid and protein
Definition
virus
Term
first to observe living microbes
Definition
Leewenhoek
Term
developed the scientific method
Definition
Koch
Term
heat resistant microbes
Definition
endospores
Term
theory stating life forms could arise from vital forces present in nonliving/decomposing matter and was disproved by Pastuer
Definition
spontaneous generation
Term
diseases were caused by growth of microbes not sins
Definition
germ theory of disease
Term
orderly arrangement of organisms into groups
Definition
classification
Term
assigning of names
Definition
nomenclature
Term
discovering and recording traits of organisms for placement into taxenomic schemes
Definition
identification
Term
long thin helical structure composed of protein flagellin
Definition
filament
Term
curved sheath
Definition
hook
Term
rings stacked anchored to cell wall that aid in motility
Definition
basal body
Term
internal flagella
Definition
axial filaments
Term
hairlike bristles that adhere to other cells
Definition
fimbriae
Term
tubular protein structure found only in gram neg cells join bacterial cells for conjugation
Definition
pili
Term
thick cell wall primarily of peptidoglycan/cell membrane. when stains it retains crysal violet and turns purple
Definition
gram positive
Term
outer cell membrane with thin peptidoglycan layer and cell membrane. Stains red from safranin
Definition
gram negative
Term
strong flexible layer helping with cell support keeping from cell burst or pressure due to changes in osmotic pressure
Definition
peptidoglycan
Term
intracellular storage bodies
Definition
granule
Term
able to withstand extreme temperatures
Definition
endospore
Term
formation of endospores
Definition
sporulation
Term
return to vegetative growth
Definition
germination
Term
shape of cocci bacteria
Definition
spherical
Term
shape of bacilli bacteria
Definition
rod
Term
defense that has a barrier to block portal of entry
Definition
first
Term
line of defense that has protective cells and fluids
Definition
second
Term
line of defense that is acquired with previous exposure to foreign body
Definition
third
Term
defense response that is the same every time
Definition
non-specific
Term
defense response that gives a unique response every exposure
Definition
specific
Term
the body's second and third lines of defense
Definition
immunology
Term
plasma like fluid
Definition
lymph
Term
function of the spleen
Definition
filter blood
Term
detect foreign bodies and signal macrophages
Definition
recognition
Term
what does pyrogensis or a fever do?
Definition
reset the hypothalamus
Term
nutrophil, eosinophil, and macrophage that extract info from foreign matter
Definition
phagocyte
Term
small protein used to produce a response to virus, antigens, and RNA
Definition
intereron
Term
production of specific antibodies by dual system of B and T lyphocytes in response to encounter of foreign body
Definition
antigen
Term
antibodies produce function against the antigen they were produced
Definition
specificity
Term
recall the first encounter with an antigen and respond to subsequent encounters
Definition
memory
Term
type of immunity that causes production of antibodies and creates memory, takes time
Definition
active immunity
Term
type of immunity that antibodies donated and does not create memory, does not take a long time
Definition
passive immunity
Term
type of immunity that is normal with life experiences
Definition
natural immunity
Term
type of immunity that is a vaccine or medical
Definition
artificial immunity
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