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causes disease only in the absence of normal host resistance |
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any situation when a microorganism is growing in a host |
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damage or injury to host that impairs host function |
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organism that lives in a host |
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microorganisms that promote health |
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nucleated white blood cells in the blood and lymph |
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-from monocyte -laced w/ tissue -antigen presenting cells (antigen recognition) ***antigen processing |
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-very large -big bad wolf -whipping bashing weapon -eat polymorphonuclear leukocytes |
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polymorphonuclear leukocytes |
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killing or removal of all viable organisms within a growth membrane |
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agents that destory or kill bacteria |
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control of microorganisms by limiting their growth but not killing them |
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agents that inhibit growth |
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treatment of an object to make it safe to handle |
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directly targets pathogens, although it may not eliminate all microorganisms |
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specialized chemical or physical agents that kill microogranisms or inhibit microbial growth |
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number of viable microorganisms |
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-decimal reduction time -time required for a 10-fold reduction in population density at a given temperature |
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a sealed heating device that allows the entrance of steam un pressure generally 10-15 minutes |
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-uses precisely controlled heat to reduce microbial populations in MILK and other heat sensitive liquids -does not kill all organisms -TB, brucellosis, Q fever & typhoid fever |
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-microwaves (thermal), UV (breaks DNA), X-Rays, Gamma rays, and electrons |
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-electromagnetic radiation of sufficient energy to produce ions with which the radiation particles collide |
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-currently used for sterilization and decontamination in medical supplies and food industries |
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-fibrous sheet or mat made form a random array of overlapping paper asbestos, borosilicate |
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high efficiency particulate air filter |
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-liquid sterilization -composed of polmers with high tensile strength -functions like a sieve trapping particles on surface |
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Nucleation Track (Nucleopore) Filter |
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-treating very thin polycarbonate films with nuclear radiation and etching film with a chemical |
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cycloserine vancomyvin bacitracin penicillins cephalosporins monobactams carbapenems |
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trimethromprim sulfonamides |
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cytoplasmic membrane structure |
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protein synthesis (30S inhibitors) |
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tetracyclines spectinomycin streptomycin gentamicin kanamycin amikacin nitrofurans |
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protein synthesis (50S inhibitors) |
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erythromycin (macrolides) chloramphenicol clindamycin lincomycin |
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DNA-directed RNA polymerase |
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nalidixic acid ciprofloxacin novobiocin --all are quinolones |
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Gm+ bacteria, Acinetobacter |
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saliva = lysozome, Lactoperoxidase, S. mutans--dental plaque and dental cares |
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dental cares, gooey polymer, lactic acdproducing |
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pH 2, helicobacter pylori, E. Coli, Clostridium, Bacteroides, |
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Normal Flora - Respiratory, Urogenital |
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->Upper RT - staph, strep, diphtehroid bacilli, Gm- cocci ->Lower RT - no resident microflora ->UTE. coli, proteus irabilis, lactobacilus acidophilus, yeasts |
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2 antigen binding sites, G1 - G4, G1 and G3 activate complement, distribution=extracellular fluid; blood and lymph, crosses placenta |
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10 antigen bidning sites, first antibody to appear after immunization, strong complement activator, distribution-blood and lymph, monomer is B cell-surface receptor |
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2 antigen binding sites, important circulating antibody, distribution=secretions, monomer in blood and dimer in secretions
4 antigen bidning sites, major secretory antibody |
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2 major antigen binding sites, minor circulating antibody, distribution=blood and lymph, B lymphocyte surfaces |
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2 antiegen bidning sites, involved in allergic reactions, CH4 contains mast cell binding fragment, distribution=blood and lymph, binds to mast cell surfaces |
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