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Microbiology
Chapter 13 Antimicrobial Therapy
5
Biology
Undergraduate 1
03/23/2008

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Term

Selective Toxicity

Definition

Toxic enough to harm the microbial agent without being toxic to the host's cells, organs, ect.

Term

Toxic Dosage Level

Definition

Dosage level that is toxic to the host.

Term

Therapeutic Dosage Level

Definition
Dosage level @ which the pathogen is successfully eliminated if taken for the recommended time frame.
Term

Minimum Inhibitiory Concentration

(MIC)

Definition

Lowest concentration of an antimicrobial agent that prevents bacterial growth in the dilution method of determining antibiotic sensitivity.

 

Determined by E (epsilometer) Test Strips, Microscan or VITEK machine.

Term

Minimum Bactericidal Concentration

(MBC)

Definition

Lowest concentration of antimicrobial agent that will kill a microorganism, as indicated by the absence of growth following subculturing in the dilution method.

 

Determined by Kirby-Bauer Disk Diffusion test.

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