Shared Flashcard Set

Details

Microbiology
Humoral (Antibody-Mediated) Immunity
8
Biology
Undergraduate 1
11/13/2007

Additional Biology Flashcards

 


 

Cards

Term
What is the humoral?
Definition
The body's fluids (blood and fluid between cells), the opposite of intracellular.
Term
Where is humoral immunity effective?
Definition
  1. Extracellular
  2. Toxins
  3. Viruses
Term
What happens in the recognition phase of humoral immunity?
Definition

The Ag recognizes and binds specifically to B cell lymphocytes based on shape.

Term
What happens in tha activation phase of humoral immunity?
Definition
  1. Clonal expansion -genetically identical clones of B cells are replicated through mitosis.
  2. The B cells are differentiated into to cells types: Effector and Memory Cells.
Term
What are effector B cell lymphocytes?
Definition
Active plasma cells that make and release protein Abs specific to Ag. They are part of the primary response.
Term
What are memory B cell lymphocytes?
Definition
The nonactive B cells that stay in the body/system for secondary reponse to a second infection of the same Ag.
Term
What is the difference between the primary and secondary response?
Definition

IgM and IgG are part of the primary response.During the first infection there is a lag period and IgM responsed fast and first. IgG respond later. During the secondary infection there is no lag time. IgM and IgG memory B Cells respond at the same time but IgG has higher concentrations and are sustained.

Term
What are the four functions of the antibodies?
Definition
  1. Antitoxin (Directly neutralizes)
  2. Virus inactivator (Directly neutralizes)
  3. Opsonin (Promotes Phagocytosis)
  4. Complement Activator (Promotes Phagocytosis)
Supporting users have an ad free experience!