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Microbiology2
Immune Response (Adaptive)
22
Biology
Undergraduate 3
11/13/2011

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Term
Most antigens are large __________ antigens
Definition
foreign
Term
The ________________ immune system produces lymphoctyes (T or B cells)
Definition
specific (adaptive)
Term
lymphocytes respond to...
Definition
foreign antigens
Term
An antigen is a substance that is capable of the production of an _______________.
Definition
antibody
Term
Helper T cells are critical in activating __________________.
Definition
B lymphocytes
Term
TH cells are required to help B cells produce ____________; they do so by releasing proteins called ______________.
Definition
antibodies
cytokines
Term
We are born with a vast repertoire of __________________
Definition
B cells
Term
Lymphocytes (B- or T-cells) that respond to a ________________.
Definition
foreign antigens
Term
Most antigens are large foreign-___________ associated with microbes, tumor cells, pollen, dust, food, etc.
Definition
proteins
Term
T lymphocytes are said to be _________________.
Definition
''sensitized'' (to certain antigens)
Term
Types of Specific Immunity (2)
Definition
1.) Humoral (antibody-mediated) immunity
2.) Cell-mediated immunity (CMI)
Term
Antibodies are only produced by ACTIVATED ________________.
Definition
B lymphocytes
Term
Humoral (antibody mediated) immunity does what?
Definition
Triggers production of antibodies specific for an antigen
Term
Cell-mediated immunity (CMI) causes what?
Definition
Production of T lymphocytes directed against an antigen
Term
Memory T cells coordinate what?
Definition
Coordinate rapid response to reinfection with same agent.
Term
Antibodies are produced by _____-cells (with the aid of _________ __________ cells)
Definition
B cells
T helper cells
Term
Plasma cells are ________________ producing cells.
Definition
antibody
Term
_______________________ are long-lived cells that provide life-long immunity to a microbe-vaccine-antigen encountered earlier. These cells respond in a matter of hours to target antigen for destruction.
Definition
Memory B cells
Term
An antibody is also known as an ___________________.
Definition
Immunoglobin
Term
Activated TC cells produce _____________, a pore-forming protein that lyses the target tumor- or infected-cell
Definition
perforin
Term
The three major types of lymphocyte are
Definition
T cells, B cells and natural killer (NK) cells
Term
Large granular lymphocytes include ____________________. Small lymphocytes consist of _________and _______________,
Definition
Natural Killer Cells
T cells and B cells
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