Shared Flashcard Set

Details

Microbiology
Streptococcus
18
Science
Graduate
05/08/2008

Additional Science Flashcards

 


 

Cards

Term
List a few characteristics of the Streptococcus species
Definition
  • GPC often in chains
  • Facultative organisms
  • Catalase negative
Term
Characteristics of Streptococcus pyogenes
Definition
Natural host/reservoir: throat or skin
Mode of transmission: direct contact/resp droplet
Clinical manifestations: various
Risk factors: ???
Characteristics: 
  • beta-hemolytic
  • bacitracin sensitive
  • Lacefield Group A
Term
Characteristics of Streptococcus agalactiae
Definition
Natural host/reservoir: GI tract, vagina
Mode of transmission: during birth
Clinical manifestations: neonatal sepsis, mennigitis
Risk factors: diabetes, difficulty labor
Characteristics: 
  • beta-hemolytic
  • bacitracin resistant
  • hippurate positive
  • Lancefield Group B
Term
Characteristics of Streptococcus pneumoniae
Definition
Natural host/reservoir: Oropharynx
Mode of transmission: respiratory droplet or contact
Clinical manif: SOB/fatigue/cough/fever/chills 
Risk factors: elderly, alcoholisms, chronic resp dx
Characteristics: 
  • alpha hemolytic
  • optochin sensitive
Term
Characteristics of Streptococcus viridans
Definition
Natural host/reservoir:   oral cavity
Mode of transmission:    direct contact
Clinical manifestations:  dental carries/endocarditis
Risk factors:                  recent dental work 
Characteristis: 
  • alpha hemolytic
  • optochin resistant
  • bile-esculin sensitive
Term
Beta hemolysis
Definition
complete lysis resulting in clearing of blood cells surrounding colony
Term
Alpha hemolysis
Definition
partial hemolysis resulting in green discoloration of blood cells surrounding colony
Term
Gamma hemolysis
Definition
non-hemolytic resulting in visible blood cells around surrounding colony
Term
Sequela
Definition
Immune mediated diseases: you get an infection that causes a disease, causes another condition b/c of the way you fight the initial disesae
 
Examples: rheumatic fever, acute glomerulonephritis 
Term
Rheumatic fever
Definition
Sx: fever after having strep throat
 
Et: antibodies targeting Streptococcus pyogenes antigens begin to cross react with heart tissue
 
Txt: Long term penicillin use 
Term
Acute glomerulonephritis
Definition
Sx: oligouria, dark/smoky urine, edema
 
Et: Antigen-antibody complexes get deposited in the glomerular basement membrane
 
*usually occurs after a skin infection 
Term
Virulence factors of S. pyogenes
Definition
  • erythogenic toxin
  • exotoxin A
  • exotoxin B
Term
Erythogenic toxin
Definition

Virulence factor of S. pyogenes

 

causes rash of scarlet fever

 

sometimes accompanies strep throat infections 

Term

Exotoxin A 

Definition

virulence factor of S. pyogenes

 

considered a "super antigen"

 

causes toxic shock syndrome 

Term

 Exotoxin B 

Definition

virulence factor of S. pyogenes

 

"flesh eating bacteria"

 

protease of necrotizing fasciitis 

Term
Streptococcus sanguis
Definition

Normal Flora of the mouth

 

Can cause endocarditis during trauma 

Term
Clostridium difficle
Definition

Normal flora of the GI

 

Can cause pseudomembranous colitis 

Term
Toxic shock syndrome
Definition

exotoxin mediated manifestation of S. pyogenes infection

 

cause by exotoxin A 

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