Term
| Staphylococci characteristics |
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Definition
- GPC in clusters
- Catalase positive
- Facultative organisms
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Term
Staph. aureus vs. Staph. epidermidis List two main differences |
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Definition
Staph. aureus. - beta hemolytic
- lg. smooth white or golden colonies
- coagulase +
Staph. epidermidis - non-hemolytic
- lg. smooth white to gray colonies
- coagulase -
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Term
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Definition
Major protein in cell wall of Staph. aureus. Binds to Fc region of IgG molecules and prevents the binding of complement and phagocytosis |
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Term
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Definition
| Part of Staph. aureus cell wall that plays a role in adherence to human cells. |
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Term
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Definition
| Enzyme found in Staph. aureus that plays a role in abscess formation |
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Term
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Definition
Enzyme found in Staphalococci species. Degrades H202 produced by PMNs |
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Term
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Definition
| Necrotizing toxin found in Staph. aureus cell wall. |
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Term
| Treatment of Staphalococci infection |
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Definition
Most organisms of this species is resistant to penicillin due to their beta-lactamase production that hydrolyzes penicillins. Use Nafcillin as first-line therapy Then use Vancomycin if resistant |
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Term
| Clinical presentations of Stapholoccoal infections |
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Definition
Abscess Skin infections -impetigo, folliculitis, cellulitis Toxin mediated infections -Scalded skin syndrome: exfoliatin -toxic shock syndrome: TSST-1 (tampon use) -Food poisoning |
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Term
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Definition
| superficial lesion in a hair follicle |
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Term
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Definition
Deeper infection involving single hair follicle (furuncle - boil) or multiple hair follicles (carbuncle)
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Term
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Definition
Common in young children, characterized by encrusted pustules on the superficial layers of the skin Highly contagious. |
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Term
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Definition
Toxin mediated infection of Stapholocci species Toxin: Exfoliatin causes sunburn-like rash followed by separation of epidermal cells *important to keep pateint from getting a secondary infection. |
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Term
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Definition
Protease that cleaves a protein that plays a role in cell to cell adhesion Involved in effects of scalded skin syndrome and peeling of skin. |
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Term
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Definition
Associated with tampon use TSST acts as a superantigen and releases large amounts of cytokines IL1, IL2, TNF multiple organ systems involved |
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Term
| What are some ways to prevent a Staphalococcal disease? |
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Definition
Wash hands Refrigerate food <5C Proper food handling |
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