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Gram Negative Facultative organisms Glucose fermenters Oxidase negative capsular antigens can be found in human/animal GI, but widely distributed |
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IL-1 release: fever TNF release: septic shock mediator Nitroic oxide release: vasodilation, hypotention Hageman factor: activation of clotting (DIC disseminated intravascular coagulation) Complent - alternative pathway |
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Contains K-1 capsule opportunistics - infects ulcers in GI lactose + EMB agar shows green sheen Clinical manifestations: UTI, neonatal meningitis/sepsis, nosocomial infections, enterocolitis |
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fecal-oral orfecal-vaginal transmission opportunistic lactose +, large capsule (mucoid colonies) Clinical manifestations: community acquired pneumonia, nosocomial infections, UTI |
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Opportunistic pathogen lactose -, swarming growth, urease + Clincal manifestations: UTI - stone formation, nosocomial infectgion - septicemia
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found in GI tract/soil/ water widely found in hospitals/environment Produces red pignment, very antibiotic resistant Clinical manifestations: nosocomial pathogen |
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warm water sources, some in GI tract opportunistic oxidase +, non-glucose fermenter, blue-green pigment (pyocyanin) very antibiotic resistant: use 3rd generation AMG Clinical manifestations: wound infections of burn pts, nosocomial infections (UTI/sepsis), pneumonia (cystic fibrosis), external ear infection, hot tub folliculitis |
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Ameobocytes will clot in the presence of minute amount of endotoxins Tag of these ameobocytes are placed with the autoclave to ensure no endotoxins are present |
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In preventing disease with enteric GNR, we can use _____________ or _____________ |
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Definition
Filtration, LAL preparations Filtration has small enough pore size such that endotoxins won't go through |
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