Term
| What are the three main characteristics of MOs that increase virulence? |
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Definition
- Pathogenicity
- Virulence
- Cellular Products - Exotoxins and Endotoxins
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Term
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Definition
The ability of a MO to cause a disease. |
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Term
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Definition
| Virulence is a measure of pathogenicity. A stronger pathogen has higher virulence. |
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Term
| What are four factors of virulence? |
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Definition
- Invasiveness
- Toxigenicity
- Capsules
- Common pili
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Term
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Definition
| Capacity of a MO to enter the host and spread. |
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Term
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Definition
| The capacity of a MO to preduce toxins. |
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Term
Of the three MO examples what are there invasiveness and toxigenicity? |
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Definition
- Clostridium botulinum - 0, Invasiveness; High, Toxigenicity
- Treponem pallidum - High, Invasiveness; 0,Toxigenicity
- Streptococcus pyogenes - moderate invasiveness; moderate toxigenicity
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Term
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Definition
- Glycocalyx - gel structure that helps MOs adhere to host and are antiphagocytic.
- Examples: Bacillus anthracis, Streptococcus pneumoniae
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Term
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Definition
| Short hair like structures on the surface of MOs that help adhere to hosts. |
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Term
| What are cellular products that increase MO virulence? |
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Definition
- Endotoxins - part of the GM- cell wall (Lipid A)
- Exotoxins - toxic proteins that are produces in the MO and secreted. (Some GM+ and GM-)
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