Term
| What causes gas gangrene? |
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Definition
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Term
| What type of gram stain is clostridium perfringens? |
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Definition
| gram positive sprote former |
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Term
| Is clostridium perfringens an aerobe or anaerobe? |
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Definition
| obligate anaerobe (cannot grow in the prescnece of oxygen) |
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Term
| What happens in gas gangrene? |
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Definition
| the bacteria degrades carbs to acid and gas (H and CO2) causing bubbling in the tissues which leads to interruption of blood flow and tissue death |
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Term
|
Definition
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Term
|
Definition
| interruption of blood flow |
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Term
|
Definition
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Term
| What are the virulence factors of gas gangrene? |
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Definition
| metabolism (gas prodctoin), toxin production |
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Term
| What are the different toxins of gas gangrene? |
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Definition
| Alpha toxin (phospholipase C), beta toxin (necrotizing toxin) |
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Term
| How do you diagnose gas gangrene? |
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Definition
| clinical signs, isolate bacteria and conduct toxin typing |
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Term
| How do you treat gas gangrene? |
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Definition
| debridement of wound and amputation, penicillin, hyperbaric oxygen, passive antibody against alpha toxin |
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Term
| What is hyperbaric oxygen? |
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Definition
| forcing oxygen into the tissues which will kill the anaerobes |
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Term
| What is the purpose of using a passive antibody against alpha toxin? |
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Definition
| give you anti toxin to stop the action of the toxin |
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Term
| How do you prevent gas gangrene? |
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Definition
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Term
| What type of gram stain is pseudomonas aeruginosa? |
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Definition
| aerobic gram-negative rod found in soil/water |
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Term
| what is pseudomonas aeruginosa assocaited with? |
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Definition
| burn wounds (wounds fluoresce due to pyocyanin or pyoverdin) |
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Term
| What kind of pathogen is pseudomonas aeruginosa? |
|
Definition
|
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Term
| what type of infection is pseudomonas aeruginosa? |
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Definition
|
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Term
| Why are pseudomonas aeruginosa so antibiotic resistant? |
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Definition
| they live in dirt with all the antibiotic producers |
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Term
| What are the virulence factors for pseudomonas aeruginosa? |
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Definition
| exotoxin A, dense biofilm in CF patients |
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