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Microbiology Gram Pos. Rods
Module 7
102
Microbiology
Graduate
03/22/2011

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Term
Corynebacterium diptheria
Definition
Gram positive rods, L or V
Term
Corynebacterium diptheria
Definition
potassium tellurite shows black colonies
Term
Corynebacterium diptheria
Definition
Elek test shows precipitin line
Term
Corynebacterium diptheria
Definition
Elek test shows precipitin line
Term
Elek test precipitin line from...
Definition
immunocomplexs formed by antitoxin from test strip and toxin from bacteria = black color
Term
Corynebacterium diptheria
Definition
grown on Loeffler's coagulated blood serum medium with methylene blue, polymerized metaphosphate granules appear beaded are babes ernst granules
Term
Corynebacterium diptheria
Definition
Elek test positive
Term
Corynebacterium diptheria, Bacillus anthracis, Listeria monotcytogenes, Bacillus cereus
Definition
aerobic
Term
diptheria toxin
Definition
this A/B toxin ADP ribosylates EF-2
Term
Corynebacterium diptheria
Definition
pseudomembrane bleeds bc of inflammatory cells which contain fibrin
Term
HBEGF on heart cells and nerve cells
Definition
diptheria toxin binds this factor
Term
Corynebacterium diptheria
Definition
low Fe = high toxin
Term
Corynebacterium diptheria
Definition
toxin encoded on lysogenic beta phage
Term
URTI, pharyngitis, bilateral cervical lymph enlargement, pseudomembrane
Definition
sypmtoms of diptheria
Term
Corynebacterium diptheria, GAS, and others
Definition
causes pharyngitis
Term
Corynebacterium diptheria
Definition
transmitted by respiratory droplets
Term
fibrin, leukocytes, necrotic ep cells, bacteria cells, Corynebacterium diptheria
Definition
pseudomembrane on pharynx is made of... and is involved with this bug
Term
Corynebacterium diptheria
Definition
treat with antitoxin, penicillin/erythromycin, DPT vx
Term
Corynebacterium diptheria DTaP
Definition
associated with herd immunity
Term
Clostridium dificile
Definition
can cause peritoneal abscess
Term
Clostridium dificile, Clostridium botulinum
Definition
gram + rod has some pink stain (spores)
Term
Clostridium dificile, Clostridium botulinum, Bacillus anthracis, Clostridium perfringens
Definition
forms spores
Term
Clostridium dificile, Clostridum botulinum, Clostridium tetani, Clostridium perfringens
Definition
anaerobic
Term
toxin B from Clostridium dificile
Definition
this toxin causes CPE
Term
toxin A of Clostridium dificile
Definition
this toxin causes fluid production and mucosal damage in GI, enterotoxin effects
Term
Clostridium dificile
Definition
antibiotic associated pseudomembranous colitis
Term
Clostridium dificile and rotavirus
Definition
causes watery diarrhea and vomiting
Term
Clostridum botulinum
Definition
mouse protection tests
Term
Clostridum botulinum
Definition
lysogenic conversion by phage
Term
Clostridum botulinum
Definition
proteolytic enzymes form gas in body and in can
Term
Clostridum botulinum
Definition
produces 8 toxins
Term
A B E
Definition
most important toxins for Clostridum botulinum
Term
toxins from Clostridum botulinum
Definition
toxin absorbed from gut, to bloodstream, to PNS, protease cleaves proteins involved in Ach release
Term
botulism
Definition
has a wound, infant, and food version
Term
Clostridum botulinum
Definition
diplopia, ascending paralysis, dilated pupils
Term
strep pn, Clostridum botulinum, and others
Definition
causes food poisoning
Term
food botulism
Definition
ds caused by preformed toxin
Term
Clostridum botulinum
Definition
trivalent antitoxin made in horses
Term
botulin toxin
Definition
heat labile toxin
Term
Bacillus anthracis, Listeria monotcytogenes
Definition
can be found in CSF
Term
Bacillus anthracis
Definition
gram + rods, boxcars in chains
Term
Bacillus anthracis
Definition
antiphagocytic capsule made of D=glutamate
Term
Bacillus anthracis
Definition
non hemolytic
Term
Bacillus anthracis
Definition
pxo1 and px02 plasmids
Term
px01
Definition
plasmid encodes exotoxin PA, LF, EF
Term
EF of Bacillus anthracis
Definition
causes inc cAMP fluid out of cells
Term
Bacillus anthracis
Definition
PA BP important for the vx for...
Term
px02
Definition
plasmid encodes poly d glu capsule
Term
Bacillus anthracis
Definition
gamma phage assay is a bacteriophage that specifically binds and lyses...
Term
inhalation anthrax
Definition
enlarged mediastinum
Term
inhalation anthrax
Definition
enlarged mediastinum
Term
Bacillus anthracis
Definition
causes high neutrophils
Term
Bacillus anthracis
Definition
causes inhalation and cutaneous dss
Term
Bacillus anthracis, hantavirus, flavivirus, togavirus
Definition
cause fever, vomiting, elarged mediastinum?
Term
Bacillus anthracis
Definition
no person to person infection in...
Term
Bacillus anthracis
Definition
Tx with cipro or doxycycline
Term
supresses cytokine response
Definition
what does LF of anthrax do?
Term
Clostridium tetani
Definition
infects umbilicus
Term
Clostridium tetani
Definition
forms a terminal spore at end of rod
Term
Clostridium tetani
Definition
exotoxin has A and B domain
Term
Clostridium tetani
Definition
local infection, systemic toxin spread, retrograde to CNS, GABA and glycine, neurons constantly firing
Term
Clostridium tetani
Definition
no tests
Term
Clostridium tetani
Definition
only 1 serotype
Term
Clostridium tetani
Definition
plasmid encodes something important?
Term
spasm of face with tetanus neonatorum
Definition
risus sardonicus
Term
Clostridium tetani, b. anracis
Definition
spores in soil
Term
Clostridium tetani
Definition
poor 02 supply makes u susceptible to...
Term
Clostridium tetani
Definition
antitoxin is immune globulin
Term
Clostridium tetani
Definition
tx with metronidazole, toxoid, pen G, resp support
Term
Listeria monotcytogenes
Definition
small beta hemolytic colonies
Term
Listeria monotcytogenes
Definition
motility umbrella agar
Term
Listeria monotcytogenes
Definition
escapes macrophage
Term
phospholipase C and listeriolysin O
Definition
L. mono escapes mac phagosome with...
Term
Listeria monotcytogenes
Definition
actin rocket
Term
Listeria monotcytogenes
Definition
heat-stable spores
Term
Listeria monotcytogenes
Definition
pseudopodia
Term
Listeria monotcytogenes
Definition
ActA receptor binds actin
Term
Listeria monotcytogenes,GBS, N meningitis, and many others
Definition
meningitis?
Term
Listeria monotcytogenes
Definition
can be confused for cocci
Term
Listeria monotcytogenes
Definition
catalase positive
Term
Listeria monotcytogenes
Definition
transmitted transplacentally
Term
Listeria monotcytogenes
Definition
tx with ampicillin and trimethoprim-sulfamethoxazole
Term
Clostridium perfringens
Definition
alpha toxin causes incomplete hemolysis beta toxin causes complete hemolysis == double hemolysis
Term
Clostridium perfringens
Definition
litmus milk test shows organism produces H2o2 and CO
Term
lecithinase (phospholipase C) - breaks down phospholipids of eu membranes
Definition
alpha toxin mode of action
Term
Clostridium perfringens
Definition
theta toxin (hemolysis), DNAase, hyaluronidase, collagenase, hemolysin
Term
Clostridium perfringens
Definition
Naeglar egg test shows precipitation in yolk agar
Term
Clostridium perfringens
Definition
causes Gas gangrene
Term
Clostridium perfringens
Definition
veg. cells are normal flora of colon and vagina
Term
Clostridium perfringens
Definition
local infection with systemic toxemia grow in traumatized tissue, esp muscle
Term
Clostridium perfringens
Definition
tx with hyperbaric O2 chamber to suppress bacteria and promote angiogenesis
Term
Bacillus cereus
Definition
fried rice
Term
Bacillus cereus
Definition
makes a toxin that inc cAMP and a superAg
Term
heat stabile - emetic and heat labile - diarrhea
Definition
2 forms of Bacillus cereus gastroenteritis
Term
Bacillus cereus, Staph aureus
Definition
food poisoning
Term
bacillus, clostridium, cornybacterium, listeria
Definition
4 gram positive rods
Term
bacillus and clostridium
Definition
form spores
Term
bacillus
Definition
aerobic
Term
clostridium
Definition
not aerobic
Term
bacillus and clostridium
Definition
gram + rods long deeply staining
Term
cornybacterium
Definition
club shaped G + rods
Term
cornybacterium and listeria
Definition
V or L G+ rods
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