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Microbiology final
Micro final
33
Microbiology
3rd Grade
12/13/2010

Additional Microbiology Flashcards

 


 

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Term
Mutation
Definition
A major source of variation within a bacterial species. It only affects a single gene.
Term
Types of Mutation: Deletion
Definition
A mutation in which part of a chromosome or DNA sequence is missing
Term
Types of Mutation: Frameshift
Definition
One or a few nucleotide sequences are deleted or inserted causing a shift in the translational reading frame
Term
Types of Mutation: Silent
Definition
A change in DNA that causes no change in the activity encoded by the gene (has no effect on the gene)
Term
Types of Mutation: Missense
Definition
A mutation that results in the substitution of an amino acid in a protein
Term
Types of Mutation: Nonsense
Definition
A base substitution in the DNA that results in a nonsense codon
Term
Nonsense Codon
Definition
A codon that does not encode any amino acid
Term
Types of Mutation: Mutagen Induced
Definition
Mutation that is induced by a mutagen
Term
Mutagen
Definition
An agent in the environment that brings about mutations
Term
Transformation
Definition
The process in which genes are transferred from one bacterium to another
Term
Transduction
Definition
The transfer of DNA from one cell to another by a bacteriaphage
Term
Bacteriaphage
Definition
Virus that effects bacteria 8===D
Term
Conjugation
Definition
Transfer of genetic material from one cell to another involving cell to cell contact
Term
Genotype
Definition
What the gene's code says
Term
Phenotype
Definition
Physical expression of the gene, influenced by the environment
Term
Wildtype
Definition
Microorganism isolated from the wild
Term
Auxotroph
Definition
A mutated microorganism that has lost a metabolic function particularly to synthesize a growth factor
Term
Prototroph
Definition
Wildtype parent to an auxotroph
Term
Prototroph
Definition
Wildtype parent to an auxotroph
Term
Types of Mutation: Null or knockout mutation
Definition
A mutation that totally inactivates the gene
Term
Types of Mutation: Reversion
Definition
When an auxotroph is changed back to the wildtype
Term
Types of Mutation: Suppressor
Definition
Mutation that overcomes the effects of the first mutation
Term
Resistant Mutant
Definition
Mutated organism that acquires resistance to some pathogen or antibiotic
Term
Ames Test
Definition
A method for detecting carcinogens
Term
Recombination
Definition
The process in which a new recombinant chromosome is formed by combining genetic material from two organisms
Term
Restriction Enzymes
Definition
They protect bacteria and foreign DNA
Term
Modification Enzymes
Definition
Modify DNA to protect it from restriction enzymes
Term
Curing
Definition
Plasmids can be eliminated from host cells using acridine mutations, UV, and ionizing radiation, thymine starvation, and growth above optimal temperatures
Term
Plasmids
Definition
circular DNA used in conjugation
Term
Fertility factors (F factor)
Definition
A plasmid that plays a major role in conjugation
Term
Resistance Factors
Definition
Often confer antibiotic resistance on the bacteria that contain them and code for enzymes capable of destroying or modifying antibiotics
Term
Generalized Transduction
Definition
All bacterial genes are transferred
Term
Specialized Transduction
Definition
A piece of cell DNA is transferred
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