Term
| Classification, Structure, Antigenicity |
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Definition
In the myxovirus group
Has a double-stranded segmented RNA genome, lipid envelope
Two main human types; A & B; type C is not usually associated with infection |
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Term
| Influenza antigens and subtypes |
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Definition
hemaglutinin (H antigen)
neuraminidase (N antigen) |
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Term
| How many H types are there? |
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Definition
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Term
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Definition
Influenza mainly infects and destroys lung cells, but may include the upper airway; sore throat and cough
Lung damage reduces airway and lung function
Mucosal damage allows secondary bacterial infection; bronchitis, sinusitis, otitis media and pneumonia |
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Term
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Definition
Nonproductive cough
Cellular damage causes release of cytokines that cause systemic symptoms: fever, myalgia, loss of appetite, mucosal inflammation |
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Term
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Definition
Acute influenza lasts 5-7 days
Convalescence may take up to 4 weeks to repair the respiratory tissues |
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Term
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Definition
Bronchitis, pneumonia
Otitis media in children
Exacerbation of asthma, cystic fibrosis, COPD |
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Term
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Definition
The normal level of infection in the community
Occurs first in children, then adults, then elderly
Lasts 8-10 weeks for each strain (can have more than one)
Influenza occurs in winter in temperate climes
Not seasonal in the tropics; occurs all year round |
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Term
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Definition
Worldwide, higher than normal epidemic incidence
A result of antigenic shift; most people lack immunity
Occurs about every 30 years |
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Term
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Definition
Highest in kids and elderly.
50-90million cases/year
300,000 hospitalizations
20,000-40,000 deaths |
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Term
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Definition
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Term
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Definition
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Term
|
Definition
Local (soreness on shot area)
Systematic (low grade fever, head ace) |
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