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(qualitative) indicates bacterium can cause disease |
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(quantitative) measure of disease potential |
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Upper Respiratory system consists of: |
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Definition
nose and throat (pharynx), including the middle ear and auditory tubes. |
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Lower respiratory system consists of: |
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larynxs, trachea, bronchial tubes, and lungs. |
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Microbial Diseases of Upper Respiratory System: |
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Definition
Streptococcus pyogenes Corynebacterium diptheriae Bordetella pertussis Neisseria meningitidis Hemophilus influenza |
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inflammation of the larynx |
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Definition
inflammation involving the tonsils |
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infection of the paranasal sinus cavity |
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inflammation of the flaplike structure of cartilage that prevents material from entering the larynx |
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Definition
Virulence Factors: Beta-hemolytic M protein Erythogenic "red forming" toxins |
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Definition
allows streptococci to escape from a fibrin clot |
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dissolves glue holding cells together. Hyaluronic acid is a major constituent of the intersitial space between cells |
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Hemolytic classification of streptococci pyogenes: |
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Definition
Beta-hemolytic streptococci are surrounded by clear, colorless zone due to COMPLETE destruction of red blood cells. |
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located in the cell wall and pili of streptococci. Encouraged adherence to pharynegeal (throat) tissue. Retards phagocytosis (white blood cells that try to kill the bacteria). Over 100 specific types of M protein have been identified. |
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Streptococcus pyogenes causes: |
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Definition
Strep throat, by AIRBORNE DROPLETS expelled by coughing or sneezing.
Scarlet fever |
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Symptoms of Strep Throat: |
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Definition
High fever, coughing, swollen lymph nodes and tonsils, fiery red throat. Complication- can also infect middle ear called otitis media |
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Symptoms of Scarlet Fever: |
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Definition
Strep throat accompanied by a skin rash. Usually only get scarlet fever once because body makes antibodies against the toxin called Antitoxin |
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"red forming" toxin produced by certain strains that carry prophage (ability of a cell to replicate) with toxin genes. Toxin damages capillaries results in blood leaking through the walls. |
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phage DNA integrates into chromosome and becomes dormant. |
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cells with phage in the chromosome |
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A change in environmental conditions can cause the prophage to come out of the chromosome. Results in phage entering LYTIC cycle and produces more phages. |
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Lysogenic strains of Streptococcus produce a extotoxin that results in: |
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Lysogenic strains of COrynebacterium diptheriae produce a potent exotoxin that is the cause of: |
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Definition
Strains of Clostridium botulinum produce the: |
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Characterized by fever and inflammation of the small blood vessels. |
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Symptoms of Rheumatic fever: |
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Definition
Joint pain, often see permanent scarring and distortion of heart valves. |
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Rheumatic Fever Glomerulonephritis Erysipelas |
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Definition
Results of untreated Streptococcal pharyngitis: |
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Definition
Very rare flesh-eating disease, streptococcus bacteria spread deep within the fascia, fibrous sheets of the connective tissue surrounding muscles and binding them to one another. |
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Definition
Disease:Strep throat, streptococcal pharyngitis
Characteristics: Red pharyngeal lining, patches of pus, pain on swallowing, enlarge tonsils and lymph nodes |
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Corynebacterium diptheriae |
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Definition
Disease: Diphtheria
Characteristics: Mild sore throat, slight fever swelling in neck, toxin production damages organs. |
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Definition
Disease: Pertussis- Whooping Cough
Characteristics: Cold-like symptoms, mucus accumulates, intense spasms of coughing. |
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Neisseria Meningitidis
Hemophilus Influenza |
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Definition
Disease: Meningitis
Characteristics: Membrane covering brain and spinal cord become inflamed. Primary to children under age 4. Severe headache, sudden high fever, stiff neck. |
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Diptheria
Agent: Corynebacterium diptheriae |
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Definition
Virulence factors: swelling in neck with formation of pseudomembrane. Produces toxin which circulates and damages receptor-specific internal organs. |
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Definition
a membrane composed of dead human and bacterial cells |
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Pertussis (whooping cough)
Agent: Bordetella Pertussis |
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Definition
Virulence factors: ciliary action is blocked by accumulations of dense masses of these bacteria in the trachea and bronchea. Toxins relesed upon bacterial cells death, and increases host's cytotoxin action causing eventual loss of ciliated cells. |
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Pertussis
"Whooping Cough" |
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Definition
1st stage: resembles a common cold
2nd stage: paroxysmal (violent spells) stage is characterized by attempts to clear the throat by coughing
3rd stage: sporadic coughing for several weeks (100 days cough) |
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layers that cover both the brain and the spinal cord. |
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An inflammation of the meninges |
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An inflammation of the brain |
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Meningococol Meningitis
Agent: Neisseria Meningitis |
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Definition
Virulence Factors: attachment pili, endotoxin, capsule
Reservoir: Human asymptomatic carriers, nose and throat flora
Transmission: airborne droplets |
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Microbial Diseases of Lower Respiratory System: |
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Definition
Tuberculosis Pneumonia Legionellosis Q Fever Psittacosis |
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Mycobacterium tuberculosis |
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Definition
Disease: Tuberculosis
Characteristics: Chronic lung disease characterized by low-grade fever, and destruction of lung tissue |
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Definition
Disease: Pneumonia
Characteristics: rust colored sputnum |
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Definition
Chronic lung disease characterized by low grade fever, weight loss and destruction of lung tissue |
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Tuberculosis
Agent: Mycobacterium tuberculosis |
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Definition
Acid fast positive, rod-shaped bacteria with a waxy cell wall that is resistant to drying and disinfectants. spread by aerosol droplets by people carrying the disease, spread by coughing, sneezing, speaking, or spiting |
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Virulence factors: can survive phagocytosis living iside macrophages and moving with them to deep lung tissue. produces tubercle (small lumps). |
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small lumps that are due to cellular immunity trying to limit the spread of the disease. |
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Disease: G+ pnemonia
Characteristics: hospital acquired infection |
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Haemophilus influenze Klebsiella pneumoniae Serratia Marcescens |
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Disease: G- pneumonia
Characteristics: compromised patients |
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Disease: "walking pneumonia"
characteristics: primary atypical pneumonia |
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Disease: Legionellosis
Characteristics: spread by air |
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Definition
Disease: Q Fever
Characteristics: Rickettsia, occurs dairy cows found in raw milk |
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Definition
Disease: psittacosis
Characteristics: Occurs in parrot and parrot like birds |
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bronchitis or bronchiolities |
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Definition
infection affecting the bronchi |
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Definition
general descriptive term which refers to the presence of fluid buildup in the lungs. |
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pneumonia that affects an entire lobe of the lung |
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Pneumonia that affects both left and right lungs |
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infection in the bronchiole respiratory passage |
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main causes of pneumonia that occurs in the hopsital |
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Pleomorphic (Mycoplasmal Pneumonia) |
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Definition
having no cell wall, cannot be treated with cell wall affecting antibiotics (penicillins) |
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Definition
Agent: Legionella pneumophilia
Virulence factors: can survive phagocytosis in compromised hosts, causes abscesses and tissue death.
Reservoir: grows in water of air-conditioning cooling towers
Symptoms: fever, dry cough with little sputum, some diarrhea and vomiting |
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Definition
Agent: Coxiella Burnetii
grows only within living tissue. Causes mild respiratory disease lasting 1-2 weeks.
Symtoms: sever headache, high fever, a dry cough.
Treatment: Tetracycline |
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Definition
Prevalent in livestock especially dairy cows, goats, and sheep due to a parasite . Humans get it by ingesting unpasteurized milk and by inhaling aerosols of microbes in dairy barns. |
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Affects parrots, parakeets, and other birds. Transmitted by inhaling airborne dust or dried droppings of infected birds. |
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Disease: Botulism
Characteristics: Exotoxin causes paralysis and respiratory failure |
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Definition
Disease: Staphylococcal food poisoning
Characteristics: Enterotoxin causes cramps, nausea, vomiting and diarrhea |
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Definition
Disease: Clostridium food poisoning
Characteristics: Enterotoxin causes cramps, abdomain pain and watery diarrhea |
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Disease: Bacillus cerus food poisoning
Characterisitcs: Enterotoxin causes cramps, diarrhea and vomiting. |
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Toxin involved in gastrointestines |
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Definition
Agent: Clostridium botulinum
Reservoid: Endospores found in intestines of humans and animals
Virulence Factor: produces an exotoxin that acts on nerves to block neuromuscular synapse transmission. |
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Fodder Disease Limber-neck Would botulism Infant botulism |
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Definition
Botulism is known to cause: |
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Definition
Mode of transmission: errant sneeze onto food. Skin infection (pimples, boils, abscesses) |
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Foodborne and Waterborne INTOXICATIONS |
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Definition
Botulism Staphylococcal food poisoning Clostridium food poinsoning Bacillus cerus food poinsoning |
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Foodborne and Waterborne INFECTIONS |
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Definition
Typhoid fever Salmonellosis Salmonellosis Shigellosis Cholera E. Coli Peptic Ulcers Campylobacterosis Listeriosis Brucellosis |
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Definition
Agent: Salmonella typhi
Reservoir: only humans
Transmission: Flies, food, fingers, feces, fomites |
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Symptoms: high fever, continual headahce,fever declines and diarrhea appears |
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Recovered patients of Typhoid Fever become chronic carriers because they harbor the microbe in their __________ |
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Agent: Salmonella enterica and its serotypes
Reservoir: Intestinal tracts of humans and animals |
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Infection of the intestinal tract |
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Symptoms: Diarrhea, stomach cramps, nausea and vomiting, some people can have no symptoms at all |
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Definition
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a syndrome manifested byy waves of intense abdominal cramps and frequent passage of small-volume, bloody mucoid stools |
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Shigella dysenteriae shigella sonnei |
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Definition
Tropical area disease:______________ U.s. diarrhea: _____________ |
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Definition
Transmission: Humans ingest the organism from feces or contaminated water. Sometimes from vegetables, eggs, shellfish, and dairy products |
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Definition
Agent: vibrio cholerae
Resevoir: contaminated water or food such as raw oysters
Virulence Factors: produces an enterotoxin |
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Definition
Symptoms: extensive diarrhea, rice-water stools, sudden loss of fluid and electrolytes causes shock, collapse, and often death. |
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Definition
There is a seventh world wide pandemic of ___________ still going on today |
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Definition
Disease: E. Coli Diarrheas
Characteristics: watery diarrhea typical traveler's diarrhea |
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Definition
Disease: Peptic Ulcers
Characteristics: adapted to survive in stomach |
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Disease: Campylobacterosis
Characteristics: Gastroenteritis from raw milk |
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Disease: Listeriosis
Characteristics: Main danger to fetus, transmitted contaminated food |
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Definition
Disease: Brucellosis
Characteristics: Undulant fever. Animal workers |
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Definition
Agent:Escherichia coli
Reservoir: One of the most prolific microorganisms in humans and other animals intestinal tracts |
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Definition
Virulence Factors: Pathogenic strains have specialzed fimbriae that allows them to bind to certain intestinal epithelial cells can be ENTEROTOXIC or ENTEROINVASIVE |
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Definition
(non-invasive) produce a enterotoxin similar to cholera which induces fluid loss in small intestine. |
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penetrate the intestinal epithelium, as in shigellosis, which primarily damages the large intestines |
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Traveler's Diarrhea (Montezuma's revenge) |
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Definition
Victims experience diarrhea within 2 weeks of traveling and the diarrhea lasts from 1 up to 10 days. |
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Peptic Ulcer
Ammonia and carbon dioxide |
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Definition
Agent: helicobacter pylori
Virulence factors: able to survive intense acidity of the stomach, secretes enzyme urease, which splits urea into ____________ and ____________. |
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can be determined by a breath test |
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Agent: Campylobacter jejuni
Reservoirs: intestinal tracts of many animals including dairy cattle, chickens and turkey. Effects poultry |
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characterized by headaches, stiff neck, delirium and coma |
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Definition
Streptococcus pyogenes produces a protein that, anchored in the cell wall and cell membrane, allows bacterial cells to adhere to teh pharyngeal tissue. This protein is called: |
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Definition
A 1 year old female was hospitalized with fever, lethargy and rash. Gram-negative, oxidase-positive cocci were cultured from her cerbrospinal flued. Her symptoms were caused by: |
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Waterhous-Friderichson syndrome |
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Definition
In some cases of meningococal meningitis, hemorrhagic lesion form in the adrenal glands, causing hormonal imbalance. This condition is called: |
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usually acquired in the hospital |
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Definition
Nosocomial infections are those that are: |
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Definition
Legionarrie's disease is characterized by a gram-___________, ________. |
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Definition
The agent of primary atypical pneumonia is: |
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Definition
Cases of legionnaire's disease have been linked to bacteria which |
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a rickettsial disease associated with livestock animals |
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Penicillin is useless for the treatment of mycoplasma pneumonia because the causitive organism |
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Mycobacterium tuberculosis |
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Definition
_______________ does not produce a toxin |
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Definition
A patient has fever, difficulty breathing, chest pains and fluid in the alveoli. Gram-positive cocci were isolated from the sputum. The patient most likely has |
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a skin rash on the palms and soles |
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Definition
The diagnosis of tuberculosis is aided by |
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diptheria and scarlet fever |
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Definition
Bacteriophages have been located in a lysogenic relationship with the causative organisms of |
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respiratory disease in compromised patients |
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Definition
serratia marcescens is currently considered to be a cause of |
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Definition
A child suffering from repeated bouts of a violent, high pitched cough is brough to her physican who will diagnose her infection as |
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Term
strep throat scarlet fever puerperal fever |
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Definition
Streptococcus pyogenes causes these diseases |
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Definition
produced by Streptococcus pyogenes and damages the capillaries |
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Definition
A pleomorphic organism with no cell wall that causes a type of pneumonia is |
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gram-negative diplococci in spinal fluid |
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Definition
An important principal criterion form the diagnosis of meningococcal meningitis is |
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Definition
An organism commonly present in air and soil that has been a concern with cooked rice that has been standing at room temperature |
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Definition
Clostridium perfringens has recieved notoriety in recent years as an important |
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Definition
Brucellosis is an occupational hazard of those qho |
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the person is intoxicated rather than infected |
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Definition
Antibiotics are of no value in treating botulism because |
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Definition
Poultry products are a likely source of infection by |
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replacement of lost fluids |
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Definition
The important consideration in treating patients who have bacterial dysentery is |
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Definition
The most common cause of traveler's diarrhea is probably |
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Definition
No diarrhea can compare with the extensive diarrhea associated with |
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Definition
most gastrointestinal infections are treated with |
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can be immunized against it |
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Definition
Travelers to cholera regions of the world |
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Definition
the _____________ enterotoxin is produced in the human intestine |
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Definition
After recovery from typhoid fever, the carriers may harbor the organism in their |
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Definition
The last pandemic of Asiatic cholera is |
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Definition
extra-chromosomal elements that contain drug-resistant genes |
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inhibiting the release of acetylcholine |
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Definition
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Definition
Probably the most potent toxin known is produced by |
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Definition
H. pylori can be detected by which of the following methods: |
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educate people to methods of sanitation and personal hygiene |
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Definition
One of the most important factors in controlling foodborne and waterborne disease is to |
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Definition
The antibiotic ceftriaxone is used to treat |
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Salmonilla enterica serotypes |
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Definition
disease that can be spread by household pets like ducks, tortoises and iguanas |
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Salmonilla enterica serotypes |
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Definition
disease that can be spread by household pets like ducks, tortoises and iguanas |
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