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organisms too small to be seen with unaided eye |
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One that is disease causing very few are pathogenic |
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Decompose organic waste
producers in the ecosystem by photosynthesis
produce industrial chemicals such as ethanol
produce fermented food such as vinegar, cheese, etc.
produce manufacturing and disease preventing products
(e.g. cellulose and insulin) |
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Knowledge of microorganisms allows humans to |
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prevent food spoilage and disease occurrence; led to aseptic techniques to prevent contamination in medicine and in microbiology laboratories |
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Naming and Classifying organisms "scientific nomenclature" |
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established by Linnaeus each has genus and specific epithet, or "species" |
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Escherichia coli (E. coli) |
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Honors the discoverer, Theodor Escherich describes the baterium's habitat, the large intestine or colon |
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clustered spherical cells
describes gold-colored colonies |
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Algae
Archaea
Bacteria
Fungi
Multicellular animal parasites
Protozoa
Viruses |
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Prokaryotes
Pepidoglycan cell walls
Binary fission
uses organic/inorganic chemicals or photosynthesis for energy |
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Prokaryotic
Lack peptidoglycan
Live in extreme environments
Include Methanogens, extreme halophiles, and extreme thermophiles |
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Eukaryotes
Chitin cell walls
use organic chemicals for energy
molds and mushrooms are multicellylar, consisting of masses of mycelia
yeasts are unicelluar |
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Eukaryotes
Absorb or ingest organic chemicals
motile via pseudopods, cilia, or flagella
ex) amoeba |
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Eukaryotes
Cellulose cell walls
photosynthesis for energy
produce molecular oxygen and organic compounds |
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Acellular
consist of DNA or RNA core
core is surrounded by protein coat
coat may be enclosed in a lipid envelope
replicate only when they are in a living host cell |
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Multicellular Animal Parasites |
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Eukaryotes
Multicellular animals
Parasitic flatworms and roundworms are called helminths
Microscopic stages in life cycle |
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Bacteria- Mitochondria and Chloroplasts originates
Archaea
Eukarya- degeneration |
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Ancestors of bacteria were first life on Earth
First microbes were observed in 1673 |
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1665 Reported that living things are composed of little boxes or cells |
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1858: Said cells arise from preexisting cells |
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All living things are composed of cells and come from preexisting cells. |
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1673-1723: described live microorganisms in Letters to the Royal Socity of London. Teeth scrapings, rain water, and peppercorn infusions. |
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the hypothesis that living organisms arise from nonliving matter; a "vital force" forms life. |
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the hypothesis that living organisms arise from preexisting life |
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Francesco Redi Experiment
1668 |
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3 jars covered with net 3 open jars
showed that: maggots came from flied and the covering was to keep flies out. Biogenesis! |
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John Needham Experiment
1745 |
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nutrient broth was heated and covered and showed microbial growth, supporting spontaneous generation! |
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Lazzaro Spallanzani Experiment
1765 |
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Sealed flask before heating and no microbial growth supporting biogenesis! |
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Demonstrated that microorganisms are in the air. First proved biogenesis through short necked flasks then used S-shaped flask to keep microbes out but to let air in. Tilted it and let microbes in and saw growth |
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Golden Age of Microbiology |
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1857- 1914: Begun with Pasteur's work discoveries included the relationship between microbes and disease, immunity, and antimicrobial drugs. |
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-the conversion of sugar to alcohol to make beer or wine -Pasteur showed that microbes are responsible for this... and spoilage of food
- Found that spoilage could be killed by heat that couldnt evaporate wine or alcohol |
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the application of a high heat for a short time |
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1835: Showed that a silkwork disead was caused by fungus |
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1865: another silkworm disease was caused by protozoan |
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1840s: advocated handwashing to prevent transmission to puerperal fever from one obstetrical patient to another |
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1827-1912: used phenol to prove that surgical wound infections were caused by microbes |
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1876: proved that a bacterium causes anthrax and provided the experimental steps, "Koch's postulates", to prove that a specific microve causes a specific disease. |
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1796: inoculated a person with cowpox virus and protected them with it. VACCINATION |
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produced from avirulent microbes, or genetic engineering |
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treatment with chemicals
antibiotics or synthetic drugs |
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Chemicals produced by bacteria and fungi that inhibit or kill other microbes |
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from treebark, used to treat malaria |
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speculated about a magic bullet that could destory a pathogen without harming the host.
-Developed a synthetic arsenic drug, salvarsan, to treat syphilis in 1910.
-Sulfonamides were synthesized in the 1930s |
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1928: Discovered first antibiotic, penicillin, that killed S. aureus 1940s: Penicillin was tested clinically and mass produced |
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study of protozoa and parasitic worms |
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-Study of immunity
-Vaccines and interferons are being investigated to prevent and cure viral diseases
-Proposed by Rebecca Lancefield in 1933 (streptococci) |
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the study of how microbes inherit traits |
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the study of how DNA directs protein synthesis |
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the study of an organism's genes; has provided new tools for classifying microorganisms |
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DNA made from two different sources |
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1960s: inserted animal DNA into bacterial DNA and the bacteria produced an animal protein. |
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genes encode cell's enzymes |
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1944 Avery, McLeod, McCarty |
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DNA is hereditary material |
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role of mRNA in protein synthesis |
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Bacteria recycle carbon, nutrients, sulfur, and phosphorus that can be used by plants and animals |
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Bacteria degrade organic matter in sewage
Bacteria degrade or detoxify pollutants such as oil and mercury |
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alternatives to pesticides, prevent insect damage
Bacillus thuringiensis infections are fatal in many insects but harmless to other animals |
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the use of microbes to produce foods and chemicals
-recombinant DNA technology
-gene therapy |
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normally present in and on human body
prevent growth of pathogens
produce growth factors (Vitamin K & folic acid)
Resistance (skin, stomach acid, and antimicrobial chemicals) |
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Microbes attach to solid surfaces and grow into masses
grow on rocks pipes teeth and medical implants |
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Emerging infectious diseases
(EIDs) |
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new or changing diseases that have potential for increasing or are increasing in incidence |
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