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Microbiology Boards
part I boards
138
Science
Graduate
02/24/2009

Additional Science Flashcards

 


 

Cards

Term
metachromatic granules seen in diptheria
Definition
Babes Ernst granules
Term
What inclusion bodies are seen in Rheumatic Fever?
Definition
Aschoff
Term
What inclusion bodies are seen in TB?
Definition

epithelioid histiocytes

Langerhans

Ghon complex in lungs

Term

Guarneri bodies

Definition
inclusion bodies of small pox
Term
Lewy bodies
Definition
seen in Parkinson's
Term
Mallory bodies
Definition
inclusion seen in Hepatitis
Term
Reed Sternberg cell
Definition

seen in Hodgkin's Lymphoma

Term

Russel Bodies

Definition
seen in plasma cells in chronic inflammation and malignant disorders
Term
type of immunity when you get measles or chicken pox
Definition
natural active
Term
type of immunity seen with the tetanus vaccine
Definition

artificial active

Term
type of immunity seen in breastfeeding
Definition
natural passive
Term
type of immunity seen in tetanus antitoxin
Definition
artificial passive
Term
where is endotoxin derived from?
Definition
lipopolysaccaride layer of gram (-) organisms
Term
what type of hypersensitivity is seen in glomerulonephritis?  Goodpasteur's syndrome?  Serum sickness?  TB?
Definition

type III

type II

type III

type IV

Term

What does the following lab tests for?

Schick

Bile solubility

Giemsa stain

Paul Bunnel

Sabouraud

 

Definition

immunity to diptheria

Pneumococci vs alpha hemolytic S. viridans

protozoa

mono

fungus

Term

What tests for the Bordet Gengou Phenomenom?

Definition

hemolysis = complement fixation

Term
What is the Coombs test and when is it used?
Definition
tests antigens on RBCs used in erythroblastosis fetalis (hemolytic anemia)
Term
What is tested in the Quellung reaction?
Definition

S. pneumoniae: checks for swelling of the capsule

Term
What is another name for the TB vaccine and what bacteria is used?  what are the major ways to test for TB?
Definition

BCG vaccine uses mycobacterium bovis

Mantoux test (PPD, type IV, skin prick)

Tine test

Term
What antigen is used in the Weil Felix test and what is being tested?
Definition

proteus vulgaris

rickettsia

Term
What tests for carcinogenicity and what bacteria is used?
Definition

Ames test

salmonella typhimurium

Term

What produces pus that is:

blue

yellow

red

yellowish green

white

Definition

Pseudomonas aeruginosa

Staph. aureus

Serratia marcesans

Gonorrhea

Chlamydia

 

Term

What is the action of sulfa drugs?

Definition
competes with PABA in gram (-) organisms
Term
What is the action of streptomycin?
Definition
inhibits protein synthesis in gram (-)
Term
What is the action of penicillin?
Definition
inhibits cell wall synthesis in gram (-)
Term
What is the action of tetracycline?
Definition
inhibits protein synthesis in gram (-) and gram (+), turns teeth yellow or gray
Term
Burnett/Metchinkoff
Definition

developed humoral theory of immunity

phagocytic theory

Term
Ehrlich
Definition

sulfa drugs

first treatment for syphillis

Term

Iwanowski

Definition

discovered tobacco mosaic virus

Term
Jenner
Definition
developed small pox vaccine
Term
Koch
Definition
proved bacteria causes diseases
Term
Rebecca Lancefield
Definition
classified streptococcus
Term
Joseph Lister
Definition
used carboxylic acid to sterilize surgical instruments (antisepsis)
Term
Pasteur
Definition

Father of Germ Theory

rabies vaccine

pasteurization

Term
 Walter Reed
Definition
yellow fever
Term

Sabin

Salk

Definition

live Polio vaccine orally

dead polio vaccine injected

Term
Semmelweiss
Definition
washing hands before surgery to prevent purperal fever contracted by women after childbirth
Term
Pyusner
Definition
discovered prions
Term
Felix d'Herelle
Definition
discovered bacteriophage
Term

Which stain tests for:

Gonorrhea

Staphylococcus

Mycobacetrium

Streptococcus

Definition

Thayer Martin (chocolate agar)

Mannitol salt

Acid fast

Blood agar

 

 

Term
direct uptake of free DNA
Definition
transformation
Term
transfer of genetic material from one bacterium to another via a bacteriophage
Definition
transduction
Term
transfer of plasmid DNA via a sex pilus (antimicrobial resistance)
Definition
conjugation
Term
incidence
Definition
# of new cases in a given period of time
Term
prevalence
Definition
total # of cases at a particular time
Term

What are the 2 most common emerging diseases?

Definition
AIDS and Ebola
Term
What are the leading causes of death in an infant?
Definition

congenital malformations

prematurity

Term
What are the leading causes of death in an adult?
Definition

heart disease

cancer

stroke

respiratory infection

accidents

Term
What are the primary steps of water purification?
Definition

filtration

flocculation

sedimentation

sludge digestion

Term
What are the secondary steps of water purification?
Definition
aeration and chlorination
Term
Which water purification step adds bacteria?  removes?
Definition

sludge digestion

sand filtration

Term
Which water purification step removes all bacteria?
Definition
chlorination
Term
What does aeration do to BOD?
Definition
decrease so that O2 is not robbed from aquatic life
Term
Which virus causes a maculopapularvesicular rash?
Definition
Varicella (chicken pox)
Term
Which viruses causes cough, coryza, and conjunctivitis?
Definition
Rubeola
Term
When is the fetus most susceptible to a Rubella infection?
Definition
first trimester
Term

What is a herpes infection of CN V called?

Definition
Gasserion ganglion
Term
Which virus causes a pink cauliflower lesion in the genital region of females?
Definition
Mulloscum Contagiosum
Term
Which virus causes parrot fever?  where is the infection seen?
Definition

Psittacosis

lower respiratory tracct

Term
Which virus causes conjunctivitis and pharyngitis?
Definition
Adenovirus
Term

What virus causes Mumps and what symptoms are associated with this infection?

Definition

 

sidomegalic paramyxoid virus

parotitis

secondary orchitis

Term

What type of fever is seen in Rubella infections?

Rubeola?

Definition

low grade fever

high grade fever

Term
Which type of infection is associated with a heterophile antibody?
Definition
Mono
Term
what virus causes childhood dysentery?  bacillary? amoebic?
Definition

coxsackie B

shigella dysentery

entamoeba histolytica

Term

what is known as anterior horn disease and how is it transmitted?

which is the deadly type?

Definition

Polio

fecal-oral

Bulbar type affects brainstem and produces respiratory paralysis

Term
What is the main cause of meningitis in newborns? infants?  adolescents?  adults?
Definition

E. coli

S. pneumoniae

N. meningitides

S. pneumoniae

Term
Which form of Hepatitis is only DNA virus?  how is it transmitted?  which is the lethal phase?
Definition

Hep B

sexual/IV drugs user

acute phase

Term
What is the #1 cause of death in AIDS?  what is the #1 fungal infection?  cancer?
Definition

Pneumocystis carinii

Toxoplasmosis

Kaposi sarcoma then Non-Hodgkins

Term
Which arbovirus has an affinity for the viscera?  What is the vector?  vaccine used?
Definition

Yellow fever

aedes agypti mosquito

Walter Reed

Term
What is also know as "breakbone fever"?
Definition

Dengue fever

first symptom is arthralgia

Term
What is the bacteria found in bubonic plague?  vector?
Definition

Yersinia pestis (pasteurella pestis)

rat flea (xenopsylla cheopis)

Term
What causes Tularemia?
Definition

Francisella tularensis

Rabbits

Term
Which bacteria is both waterborne and soil borne?
Definition
Shigella
Term
Which bacterial disease will not produce lymph swelling?  what does it cause?
Definition

Vibrio cholera

rice water stools

Term
What does enterotoxigenic E. coli produce?  enterohemorrhagic?  Which is deadly?
Definition

traveller's diarrhea and Montezuma's revenge

Hamburger's disease (deadly)

Term
What causes floppy baby syndrome?
Definition
C. botulinum
Term
What is added to meats to prevent botulism?
Definition
nitrates
Term
What is the #1 cause of food poisoning?
Definition
Salmonella
Term
What causes rose-colored spots on the abdomen?
Definition
Salmonella typhi (Typhoid fever)
Term
Which bacteria likes to hide in Peyer's patches and what test can be used to identify?
Definition

Salmonella typhi

Widal test

Term
What is the most common cause of gastritis?
Definition
Camphylobacter jejuni
Term
Which bacetria causes abdominal pain, infectious diarrhea, fever, blood and pus in stools?
Definition

Camphylobacter

Term
What causes Woolsorter's disease?
Definition
Bacillus anthracis
Term
What causes trismus?  mechanism of action?
Definition

Clostridium tetani

inhibits GABA and glycine

Term
If a patient has yellowing of the sclera and skin, what infection is likely?
Definition

spirochete

Leptospirosis (hemorrhagic jaundice)

Weil's disease

Term
What are the 3 virulence factors that fungi possess?
Definition

keratinase

proteinase

elastase

Term
What organism produces erythema chronicum migricans?
Definition

spirochete 

bulls eye rash

Borrelia burgdorferi (deer tick)

Term
What organism causes Yaws?  how is it transmitted?
Definition

Treponema pertenue (non-venereal syphillus)

casual contact

Term
Which bacteria produces coagulase?  function?
Definition

staph

catalyzes formation of fibrin from fibrinogen

Term
What bacteria produces hemolysin?  function?
Definition

staph

breaks down RBCs

Term
Which bacteria produce hyaluronidase?  function?
Definition

staph, strep, clostridia

facilitates dissemination of microorganisms through skin tissue

Term
Which bacteria produce leukocidin?  function?
Definition

strep or staph

exotoxin that kills WBCs and phagocytes

Term
What tests would diagnose ringworm infection?
Definition

fluorescence under wood lamp

skin scrapings

scrapings tested in KOH solution

Term
Which organism causes AIDS diarrhea?  what is the infective stage?  how is it transmitted?
Definition

Giardia lamblia

cyst stage

hikers drinking contaminated stream water

Term
Which organism causes anemia or chronic splenomegaly?  how is transmitted?  which is the most fatal form?
Definition

Plasmodium (malaria)

anopheles mosquito (sporozoites stage)

Plasmodium falciparum (Black water fever)

Term

In what stage does malaria travel through the body?  What protects you from malaria?

Definition

merozoite stage

sickel cell anemia

Term
Which is the most common roundworm?  wher does it reside?  how is it transmitted?
Definition

Ascariasis

in the small intestine (colicky pain)

fecal-oral

Term
Which is the most common hookworm in the US?  how is it transmitted?
Definition

Necator americanus

walking barefoot on contaminated soil

Term
What is the most common helminth worldwide?  What does it cause?
Definition

Enterobius vermicularis

itchy bum syndrome, nocturnal anal itching

Term
Which organism infects muscle?  what is most common?  how is it transmitted?
Definition

Trichinella spiralis

intercostals and diaphragm

raw pork

Term
What causes River blindness? 
Definition
Onchocarca volvulus
Term

Which is the tapeworm found in:

dog

fish

pork

beef

Definition

Echinococcus granulosus

Diphyllobothrium latum

Taenia solium

Taenia saginata

Term
What is the proglottids of tapeworms?  Which tapeworm causes cysticercosis?  Which causes pernicious anemia?
Definition

egg generating segment (fertilize self)

Taenia solium

Diphyllobathrium latum

Term
What is the most common cause of death from a helminth?  What is its primary host?  secondary?
Definition

Shistosoma japonicum (infects liver)

snail

humans

Term
What causes hemoptysis?  How is it spread?
Definition

Paragonimus westermani

crayfish, mouth

Term

Which liver fluke is from fish?  aquatic plants?

What is the intestinal fluke?

Definition

Clonorchis sinensis

Fasciolopsis hepatica

Fasciolopsis buski

Term
Which vaccines are made from chick embryo?
Definition
measles and mumps
Term
Which vaccines are made from human diploid cells?  monkey kidney tissue?
Definition

rubella, rabies, and Hep A

Polio

Term
What organism causes whooping cough and when do you hear the whoop?
Definition

Bordetella pertussis

inspiration

Term
What organism causes San Joaquin Valley Fever?  What type of areas are common?
Definition

Coccidiodomycosis

dry, temperate areas

Term
What is also known as Moniliasis and what organism causes it?
Definition

oral thrush

candida albicans

Term
What organism causes pink eye?
Definition
Haemophilus aegyptius (Koch-Weeks bacillus)
Term
What organism causes Ohio and Mississippi Valley fever?  What is a common misdiagnosis?
Definition

Histoplasmosis

calcific lesions in the lung similar to TB

Term
What causes Pontiac fever and how is it spread?
Definition

Legionella pneumophilia

water droplets that accummulate in ventilation systems

Term
What is the #1 cause of atypical pneumoniae?  Why is it atypical?
Definition

Mycobacterium pneumoniae

lacks a cell wall

Term
What is the #1 cause of pneumoniae in cystic fibrosis patients?
Definition
Pseudomonas aeruginosa
Term
What is the best way to prevent Rickettsia infection?
Definition
bug repellant
Term
What organisms are not destroyed by autoclave?  why?
Definition

Prions

acellular proteinaceous particles so no membrane for autoclave to denature

Term
Someone walking in a greenhouse is likely to get?
Definition

Sprortrichosis (sprotherix schenckii)

from rose bush throns

Term
Someone who has a peanut allergy could be sensitive to?  what does it produce?
Definition

Asperigillosis (asperigillus fumigatus)

aflatoxin (primary liver cancer)

Term
What is the #1 cause of otitis media?  otitis externa?
Definition

Haemophilus influenza

E.coli

Term
What are the common criteria to diagnose Rheumatic Fever?
Definition

carditis (maccallum's patch seen in L atria)

syndenham's chorea

subcutaneous nodules

erythema marginatum

migratory polyartherits

Term
How do we classify organisms?
Definition
Family and genus
Term
How do we name organisms?
Definition
genus and species
Term
What is released when the cell is exposed to a virus?
Definition
interferons
Term
Which interleukin is the Tcell growth factor?  from where?
Definition

IL-2

CD4 cells

Term
Which interleukin is produced by the CNS?  function?
Definition

IL-1

from macrophages to activate CD4

Term
Which viruses are the exceptions to respiratory transmission?
Definition

Polio (fecal-oral)

Hep (sexual, fecal-oral, blood)

Term
What are the Gram (+) organisms?
Definition

Staph

Strep

Clostridium

Bacillus

Corynebacterium dyptheria

Listeria monocytogenes

Term
What is the most common cause of Impetigo?  second most common?
Definition

stap. aureus

strep. pyogenes

Term
What are the diseases caused by S. pyogenes?
Definition

strep throat

rheumatic fever

glomerulonephritis

scarlet fever

erysipelas

impetigo

Term
What diseases are caused by staph. aureus?
Definition

osteomyelitis

toxic shock syndrome

scalded skin syndrome

carbuncles

impetigo

 

Term

What is the most prevalent cause of lower respiratory infection in children?

Definition
RSV
Term
What type of reaction is caused by a soluble antigen and specific antibody?
Definition
precipitation
Term

Eccymosis is seen in what type of deficiency?

Definition
Scurvy since Vit C is required for collagen formation
Term
What ingredient is diminished from milk left standing?
Definition
riboflavin
Term
bacteriostatic
Definition

inhibits bacterial replication

can restore function when removed 

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