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-Bacteria -Archaea -Fungi -Protozoa -Algae -Viruses -Multicellular Animal Parasites |
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Established the system of scientific nomenclature in 1735 |
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Description of scientific names |
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-Are italicized or underlined - the genus is capitalized; the specific epithet is lowercase -Are "Latinized" and used worldwide -May be descriptive or honor a scientist |
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-Prokaryotes (”Prenucleus") -Single-celled -Peptidoglycan cell walls -Divide via binary fission -Derive nutrition from organic or inorganic chemicals or photosynthesis |
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-Prokaryotes -Lack peptidoglycan cell walls -Often live in extreme environments Include: Methanogens, Extreme halophiles, Extreme thermophiles |
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-Eukaryotes (Distinct nucleus_ -Chitin cell walls -Absorb organic chemicals for energy -Yeasts are unicellular -Molds and mushrooms are multicellular -Molds consist of masses of mycelia, which are composed of filaments called hyphae |
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-Eukaryotes -Absorb or ingest organic chemicals -May be motile via pseudopods, cilia, or flagella -Free-living or parasitic (derive nutrients from a living host) |
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-Eukaryotes -Cellulose cell walls -Found in freshwater, saltwater, and soil -Use photosynthesis for energy -Produce oxygen and carbohydrates |
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-Acellular -Consist of DNA or RNA core -Core is surrounded by a protein coat -Coat may be enclosed in a lipid envelope -Are replicated only when they are in a livinghost cell -Inert outside living hosts |
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Multicellular animal parasites |
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-Eukaryotes -Multicellular animals -Not strictly microorganisms -Parasitic flatworms and roundworms are called helminths -Some microscopic stages in their life cycles |
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Classification of microorganisms |
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Developed by Carl Woese Three domains based on cellular organization: 1) Bacteria - cell walls contain peptidoglycan 2) Archaea - cell walls (if present) lack peptidoglycan 3) Eukarya include: -Protists - slime molds, protozoa, algae -Fungi - unicellular yeasts, multicellular molds, mushrooms -Plants - mosses, ferns, conifers, flowering plants -Animals - sponges, worms, insects, vertebrates |
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-Reported that living things are composed of little boxes, or "cells" -Marked the beginning of cell theory: All living things are composed of cells |
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-Observed the first microbes between 1623-1673. -"Animalcules" viewed through magnifying lenses |
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Golden Age of microbiology |
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1857–1914 -Beginning with Pasteur's work, discoveries included the relationship between microbes and disease, immunity, and antimicrobial drugs |
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Louis Pasteur (1822-1895) |
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-Pasteur showed that microbes are responsible for fermentation -Fermentation is the microbial conversion of sugar to alcohol in the absence of air -Microbial growth is also responsible for spoilage of food and beverages -Bacteria that use air spoil wine by turning it to vinegar (acetic acid) -Pasteur demonstrated that these spoilage bacteria could be killed by heat that was not hot enough to evaporate the alcohol in wine -Pasteurization is the application of a high heat for a short time to kill harmful bacteria in beverages |
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Joseph Lister (1827-1912) |
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Performed surgery under aseptic conditions using phenol. Proved that microbes caused surgical wound infections. |
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Established experimental steps for directly linking a specific microbe to a specific disease. |
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1796: Edward Jenner inoculated a person with cowpox virus, who was then immune from smallpox Vaccination is derived from the Latin word vacca, meaning cow The protection is called immunity |
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Louis Pasteur (1822-1895) |
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-Pasteur showed that microbes are responsible for fermentation -Fermentation is the microbial conversion of sugar to alcohol in the absence of air -Microbial growth is also responsible for spoilage of food and beverages -Bacteria that use air spoil wine by turning it to vinegar (acetic acid) -Pasteur demonstrated that these spoilage bacteria could be killed by heat that was not hot enough to evaporate the alcohol in wine -Pasteurization is the application of a high heat for a short time to kill harmful bacteria in beverages |
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Two types of chemotherapeutic agents |
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Synthetic and Antibiotics |
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Classified streptococci based on their cell wall components in 1933. This was a major advance in immunology. |
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The study of how DNA directs protein synthesis |
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The study of an organism's genes; has provided new tools for classifying microorganisms |
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DNA made from two different sources -In the 1960s, Paul Berg inserted animal DNA into bacterial DNA, and the bacteria produced an animal protein |
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Microbes normally present in and on the human body -Bacteria were once classified as plants, giving rise to the term flora for microbes This term has been replaced by microbiota -Normal microbiota prevent growth of pathogens -Normal microbiota produce growth factors such as vitamins B and K -Resistance is the ability of the body to ward off disease -Resistance factors include skin, stomach acid, and antimicrobial chemicals |
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Middle East Respiratory Syndrome -Caused by Middle East respiratory syndrome coronavirus (MERS-CoV) -Common to SARS -Severe acute respiratory syndrome -100 deaths in the Middle East from 2012 to 2014 |
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-Influenza A virus -Primarily in waterfowl and poultry -Sustained human-to-human transmission has not yet occurred |
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Methicillin-resistant Staphylococcus aureus -1950s: Penicillin resistance developed -1980s: Methicillin resistance -1990s: MRSA resistance to vancomycin reported -VISA: vancomycin-intermediate S. aureus -VRSA: vancomycin-resistant S. aureus |
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West Nile encephalitis -Caused by West Nile virus -First diagnosed in the West Nile region of Uganda in 1937 -Appeared in New York City in 1999 -In nonmigratory birds in 48 states -Transmitted between birds and to horses and humans by mosquitoes |
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Bovine spongiform encephalopathy |
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-Caused by a prion -An infectious protein that also causes Creutzfeldt-Jakob disease (CJD) -New variant of CJD in humans is related to cattle that have been given feed made from prion-infected sheep |
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-Toxin-producing strain of E. coli -First seen in 1982; causes bloody diarrhea -Leading cause of diarrhea worldwide |
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Ebola hemorrhagic fever -Ebola virus -Causes fever, hemorrhaging, and blood clotting -Transmitted via contact with infected blood or body fluids -First identified near Ebola River, Congo -2014 outbreak in Guinea; hundreds killed |
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-Cryptosporidium protozoa -First reported in 1976 -Causes 30% of diarrheal illness in developing countries -In the United States, transmitted via water |
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-Acquired Immunodeficiency Syndrome -Caused by human immunodeficiency virus (HIV) -First identified in 1981 -Sexually transmitted infection affecting males and females -Worldwide epidemic infecting 35 million people;6000 new infections every day -HIV/AIDS in the United States: 26% are female, and 49% are African American |
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