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Microbio
Random Microbio Facts
86
Medical
Graduate
06/27/2012

Additional Medical Flashcards

 


 

Cards

Term
Legionella Pneumophilia
Definition
This bacteria is water-loving and is commonly found in air conditioners, mist machines, and other water reservoirs.  It is a gram-negative organism and the first line of treatment is a macrolide such as erythromycin or azithromycin
Term
Klebsiella Pneumonia
Definition
commonly found in alcoholic and elderly patients.  These patients are at a high risk for aspiration
Term
Mycoplasma Pneumoniae
Definition
commonly found in young adult patients.  These patients will present with positive cold-agglutinin test. 
Term
Group B Strep
Definition
common cause of pneumonia in newborns
Term
H. Influenza
Definition
commonly found in pneumonia patients with COPD
Term
Naegleria Fowleri
Definition
This protozoa causes a rapidly fatal meningoencephalitis.  It is contracted by swimming in freshwater lakes or by using nasal irrigation systems known as neti pots.  This organism enters via the cribiform plate and usually infects the frontal lobes first.  Symptoms include nausea, headache, fever, loss of consciousness, and a stiff neck. 
Term
Toxoplasma Gondii
Definition
can be contracted congenitally producing a triad of chorioreinitis, hydrocephalus, and intracranial calcifications.
Term
Taenia Solium
Definition
a helminth transmitted by undercooked pork.  Ingesting the eggs of this organism causes cysticercosis and neurocysticercosis. The eggs invade the brain producing calcified cysts causing seizures. 
Term
Entamoeba Histolytica
Definition
produces bloody diarrhea and liver abscesses.  The eggs get into the liver to produce anchovy paste abscesses and right upper quadrant pain. The eggs produce flask shaped ulcers in the intestine.  This organism is transmitted by cysts in the water. 
Term
Cryptococcus Neoformans
Definition
the most common CNS fungal infection in AIDS.  The budding yeast shape are visible with India Ink stain. 
Term
Herpes
Definition
positive Tzanck test
Term
H. pylori
Definition
gram-negative, curved bacillus that produces urease
Term
E. coli
Definition
gram-negative, oxidase negative bacilli that ferment lactose and are capable of causing a variety of infections in human
Term
Neisseria
Definition
gram-negative, oxidase positive diplococci
Term
Campylobacter Jejuni
Definition
gram-negative, spiral bacillus that does not produce urease.  The bacterium is often contracted via contaminated chicken and causes inflammatory diarrhea in humans
Term
Bacillus Cereus
Definition
gram-positive bacilli that produce spores, common food contaminant and may cause gastrointestinal symptoms within a few hours following ingestion
Term
Clostridium Difficile
Definition
gram-positive bacilli that produce spores, major cause of pseudomembranous colitis
Term
Mycoplasma Pneumoniae
Definition
most common cause of acute bronchitis in non-smokers.  Patients with bronchitis present with dry cough, fever, sore throat, and tight breath sounds. Treatment of this infection is usually self-limiting. 
Term
Strep Pneumoniae and H. Influenza
Definition
common cause of bronchitis in smokers
Term
Pseudomonas Aeruginosa
Definition
a lactose negative oxidase positive organism commonly responsible for infection in cystic fibrosis patients
Term
Staph Aureus
Definition
commonly found in nosocomial pneumonia patients. 
Term
Mycoplasma Pneumoniae
Definition
A high cold agglutinin titer
Term
N. meningitidis
Definition
maltose positive test
Term

Human Herpes Virus 6

(Roseola)

Definition
most common in children between 6 and 15 months old.  It presents with a high fever for 3-5 days and a rash that appears as the fever breaks.   The rash is typically a faint macular rash that begins on the trunk and spreads to the extremities and face.  It does not usually itch and will go away on its own in a few days.  It is a similar rash to the one seen in rubella
Term
VZV
Definition
vesicular rash starting on the trunk and spreading out with lesions in various stages of healing.  It is very itchy and contagious.
Term
Rubeola
Definition
cause of measles.  The rash seen in measles is maculopapular and spreads starting from the head and moving down the body.  It usually shows up a few days after fever begins.  characterized by cough, coryza, conjunctivitis, and koplik spots
Term
Parvovirus B19
Definition
the cause of erythema infectiosum or fifth’s disease.  Initially it causes a slapped cheek appearance and then the rash spreads over the body in a lacy, reticulated pattern.
Term
Candida Albicans
Definition
the most common cause of vaginitis (commonly called a yeast infection). Diabetes and recent treatment with antibiotics are risk factors. While antibiotics are often effective in the treatment of urinary tract infections, they can also kill off the normal flora of the vagina, opening the door for fungal infection
Term
E. coli
Definition
the most common cause of urinary tract infectio
Term
Chlamydia Trachomatis
Definition
the most common cause of sexually transmitted infection and cervicitis, can cause pelvic inflammatory disease (PID), but it does not typically cause vaginal itching.
Term
Trichomonas Vaginalis
Definition
causes a thick, sometimes "frothy", greenish, foul-smelling discharge and is not associated with diabetes and recent antibiotic use.
Term

Organisms that end in -ella

(Francisella, Brucella, Legionella, Pasteurella)

Definition
commonly cultured with Charcoal Yeast Extract agar, require cysteine for growth
Term
Vibrio Cholerae
Definition
Thiosulfate Citrate Bile Salts for culture
Term
Mycobacterium
Definition
Lowenstein-Jensen medium
Term
Neisseria and Haemophilus
Definition
Chocolate Agar
Term
Neisseria
Definition
Thayer-Martin Medium
Term
Mycoplasma Pneumoniae
Definition
the most common atypical pneumonia in young adults.  An older male in the sixth decade makes this less likely.  This organism has no cell wall, and contains sterols in the membrane.  The P1 protein allows to attach to the respiratory epithelium
Term
Streptococcus Pneumoniae
Definition
the most common cause of pneumonia, especially in the sixth decade of life.  Patients will have a productive cough with rusty colored sputum.  Chest radiograph will demonstrate lobar consolidation
Term
Streptococcus Pneumoniae
Definition
most common cause of community-acquired pneumonia and is a gram-positive coccus, catalase negative, alpha-hemolytic, quellung positive, optochin sensitive, and bile soluble
Term

Strep. Pneumoniae, H. influenza type B, Neisseria Meningitidis, Salmonella, Klebsiella, Group B Strep

 

(Kapsules Shield SHiNS (group B))

Definition
Quellung reaction tests the organism for the presence of a capsule by adding animal sera that contains capsular antibodies. The antibodies cause agglutination and allows for the visualization of the organisms capsule
Term
H. Influenza
Definition
Gram-negative coccobacillus which is the second leading cause of community-acquired pneumonia
Term
Moraxella Catarrhalis
Definition
Gram-negative diplococci, also in the top 10 bacterial causes of pneumonia
Term
Doxycycline
Definition
a tetracycline used in the treatment of specific gram negative infections, such as Chlamydia trachomatis, Helicobacter pylori, Ureaplasma urealyticum, and Boriella burgdorferi
Term
Byssinosis
Definition
occurs in workers in textile factories.  This is due to exposure to gram-negative bacteria on the cotton
Term
Gardenerella Vaginalis
Definition
typically presents as a gray-colored vaginal discharge. It is often described as having a fishy odor, particularly after intercourse. It is not usually painful or pruritic, and may be entirely asymptomatic. Diagnosis is confirmed on wet mount, when “clue cells” — vaginal squamous epithelial cells covered in bacteria — are seen. Metronidazole is the treatment of choice. 
Term
Neisseria Gonorrhea
Definition
Ceftriaxone is a third generation cephalosporin used to treat gram negative infections. It is the treatment of choice for this bacteria
Term
Ciprofloxacin
Definition
a fluoroquinolone, which are used to treat gram negative infections of the gastrointestinal and genitourinary systems
Term
Mycoplasma Pneumoniae
Definition
patients have severe constitutional symptoms, a gradual onset of cough and fever, and extensive infiltrates on chest X-ray. Auto-antibodies against red blood cells may be produced during infection and can give rise to cold agglutinins. Cold agglutinins are IgM antibodies that agglutinate red blood cells at 4-degrees Celcius (cold) but not 37-degrees Celcius. These antibodies can also cause autoimmune hemolytic anemia which can account for the elevated reticulocytes in this patient
Term

Erythromycin

(macrolide)

Definition
drug of choice for atypical community acquired pneumonia
Term
Clindamycin
Definition
typically used for anaerobes that affect the GI tract
Term
Treponema Pallidum
Definition
Penicillin G is the intravenous form of penicillin. Penicillins are typically used to treat gram positive streptococcal infections. It is also the treatment of choice for this bug. 
Term
Mycobacteria
Definition
 have peptidoglycan rich membranes. The high lipid content is the reason why these organisms are acid-fast
Term
EBV
Definition
causing infectious mononucleosis a/w splenomegaly
Term
Linezolid
Definition
protein synthesis inhibitor used for vancomycin-resistant gram-positive cocci
Term
Hantavirus
Definition
This virus is found in the southwestern United States, Grand Canyon. infections have ARDS, Patients with infection will have ARDS, hemorrhage, and renal failure. Currently, there is no effective treatment and this infection has a high mortality rate
Term
Blastomyces
Definition
commonly found in the southeastern United States. These are associated with beavers and the fungus presents with skin and lung manifestations
Term
Histoplasmosis
Definition
found in Ohio and Indiana. This is commonly found in feces of bats and starlings
Term
Cryptococcus
Definition
found in pigeon excreta around building or on rooftops
Term
Mucor species
Definition
wide angled hyphae that commonly present in diabetic ketoacidosis patients
Term
thermophilic actinomycetes (saccharopolyspora)
Definition
Farmer’s lung, which is a hypersensitivity pneumonitis.  This disorder is a result of exposure to ? in moldy hay.  Patients with this disorder will not respond to albuterol.  
Term
Silo Filler's disease
Definition
often a result of bacteria fermentation in silos.  This causes a buildup of nitrogen gas in the silo and people who commonly work in this environment will develop an immediate hypersensitivity with dyspnea
Term
Gentamicin
Definition
an aminoglycoside. It binds to the 30S ribosomal subunit thus inhibiting the formation of the initiation complex for protein synthesis. It also causes misreading of the mRNA code
Term

JC Virus

(Polyomavirus)

Definition
Causes Progressive multifocal leukoencephalopathy (PML). Attacks oligodendrocytes, the myelin producing cells of the central nervous system.  This leads to multifocal demyelination in the brain and cerebellum.  This virus is present in most of the population but symptoms only arise in immunocompromised patients.  This infection commonly associated with human immunodeficiency virus (HIV)
Term
Rubeola Virus (measles)
Definition
Causes Subacute sclerosing panencephalitis found in children or young adults.  It is a rare syndrome characterized by seizures, weak limbs, and cognitive decline
Term
Indinavir
Definition

side effects include kidney stones and increased blood sugar

anti-retroviral drug

Term
Rubeola Virus
Definition
diagnosed by cough, conjunctivitis, coryza, and koplick spots.  A complication a few years after the initial infection is subacute sclerosing panencephalitis
Term
Rabies Virus
Definition
presents after being bit by an infected animal.  The symptoms start with fever, headache, and pain at the wound site and progress to seizures and the classic “foaming at the mouth.” This virus is a bullet shaped virus of the rhabdovirus family
Term
Trypanosoma Cruzi
Definition
occurs in Central and South America. The chronic form is characterized by megacolon, achalasia and myocarditis which can precipitate arrhythmia
Term

Trypanosoma Cruzi

(chaga's disease)

Definition
Exposure to the reduviid bug is the cause
Term
Legionella
Definition
found in water sources, causes pneumonia and its antigen can be detected clinically in urine
Term
Entamoeba Histolytica
Definition
causes amoebic dysentery and liver abscesses. It is an anaerobic protozoan parasite that infects when it is ingested as a cyst at which point it enters its trophozoite (active) phase. The organism can bore into the intestine and reach the bloodstream for transport to other organs including the liver where it can cause abscesses that are deadly if untreated. The organism can often be seen upon microscopy with ingested RBC's in its cytoplasm
Term
Leishmania Donovani
Definition
disease transmitted by the sandfly
Term
Metronidazole
Definition
a 5-nitromidazole that reacts with intracellular macromolecules of anaerobes and the drug of choice in treating giardia infection. When alcohol is consumed, it may result in a disulfiram-like reaction.
Term
Tinidazole
Definition
has fewer side effects than metronidazole and is the initial drug of choice for giardiasis outside of the U.S
Term
Quinacrine
Definition
 used for giardiasis, but it is not associated with a disulfiram-like reaction. It is the drug of choice for metronidazole-resistant giardiasis or in patients who cannot receive (or tolerate) metronidazole. However, this medication is not commecially available in the U.S
Term
Mebendazole
Definition
used for the treatment of roundworm and tapeworm infections; while teratogenic, it has minimal adverse effects in the adult
Term
Prazquintal
Definition
is for tapeworm and fluke infections, with minor gastrointestinal and neurologic disturbances reported as its primary side effects
Term
Niclosamide
Definition
also prescribed for tapewoms and flukes
Term
Oral Vancomycin
Definition
the drug of choice for C. difficile infection and has the side-effect of facial flushing. It inhibits cell wall synthesis by binding to the D-Ala terminus of peptidoglycan preventing elongation of the chain. 
Term
beta-lactam antibiotics which include the penicillins, cephalosporins, monobactams and carbapenems
Definition
Inhibition of the transpeptidase reaction in cell wall synthesis
Term
Bacitracin
Definition
Interference with the lipid carrier in peptidoglycan synthesis
Term
Fosfomycin
Definition
Inhibited synthesis of n-acetylmuramic acid
Term
Staph. epidermitis
Definition
associated with osteomyelitis in patient’s with prostheses
Term
Neisserria Gonorrhea
Definition
a source of osteomyelitis in sexually active individuals
Term
pseudomonas aeruginosa
Definition
Osteomyelitis in diabetics and IV drug abusers
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