Term
| What is genome reassortment? Which virus families can do it? |
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Definition
-RNA exchange between related viruses
-Only the viruses with segmented RNA can do it (all -RNA); arena, bunya, roe, & orthomyxo |
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Term
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Definition
-When viral gene or proteins rectify a defect in a related virus
-Can turn a latent infection pathogenic |
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Term
| What is phenotypic masking/mixing? |
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Definition
| -When you have different glycoproteins on the capsid (like polio 1 with a polio 2 capsid) |
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Term
Define;
-Horozontal spread
-Vertical spread
-Arboviruses
-Zoonosis
-Iatrogenic |
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Definition
-Horozontal spread; person to person
-Vertical spread; mother to child
-Arboviruses; insects carry
-Zoonosis; spread by animals
-Iatrogenic; from medical practice |
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Term
| How do we treat herpes viruses? What do they target? |
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Definition
-With **acyclovir (all) or gancyclovir (for CMV)
-Target viral *thymidine kinase and viral *DNA pol |
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Term
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Definition
-Drug for CMV retinitis
-Can also block HIV RT
-It is a phosphate analog |
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Term
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Definition
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