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worms, some of which are parasitic to humans |
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Helminths belong to one of three groups: |
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1. Cestodes (tapeworms), 2.Trematodes (flukes), and 3. Nematodes (roundworms). |
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It is estimated that at least _______% of world’s population is infected with a parasitic helminth |
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Helminths live in both the |
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body spaces (gut lumen, bile ducts, lungs, oral cavity, etc.) and in tissues (blood, muscles and skin) |
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The mode of transmission to humans varies from species to species, and includes: |
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1.ingestion of larva in raw or undercooked pork, beef or fish 2. ingestion of helminth eggs in feces, 3. by insect bites 4. by direct skin penetration |
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Pathology with infection of helminths :#1 |
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Immune responses to adult, larval or eggs stages of the lifecycle (for example with the schistosomes). |
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Pathology with infection of helminths :#2 |
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High densities of adult parasites feeding on host tissues, causing tissue damage (for example many of the digenean flukes), |
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Pathology with infection of helminths :#3 |
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Obstruction of the gut, (as may be the case with Ascaris infections) |
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Pathology with infection of helminths :#4 |
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Obstruction of lymphatic drainage (as seen with lymphatic filariasis, although in this case this is a gross simplification of what happens). |
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Pathology with infection of helminths :#5 |
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Depletion of nutrients or other metabolites required by the host |
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Pathology with infection of helminths :#6 |
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Parasites feeding on blood, causing anaemia |
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Example of pathology of depletion of nutrients |
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What does a deficeincy of vitamin B12 lead to |
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Helminth responsible for vitamin B12 depletion |
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Diphylobothrium latum aka Fishtape worm |
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Example of a Parasite that feeds on blood |
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The cestodes (tapeworms) have this type of shape |
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are ribbon-like, segmented worms |
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primarily intestinal parasites |
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cestodes (tapeworms) totally lack a |
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Due to their lack of a digestive system cestodes (Tapeworms) do not ingest |
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cestodes (Tapeworms)gain nutirients by |
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absorbing soluble nutrients directly through their cuticle |
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What will be found in stools of patients who have cestodes (tapeworm) |
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Cestodes (Tapeworm) cause clinical injury by |
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sequestering the host’s nutrients |
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Cestodes (tapeworm) cause clinical injury by excreting |
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toxic waste and massive infestation |
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Cestodes cause clinical injury by causing mechanical blockage |
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Hymenolepis nana is the smallest of all tapeworms aka the |
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Symptoms of the Hymenolepis nana (dwarf tapeworm) are: |
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anorexia, abdominal pain, and diarrhea, however, symptoms often go unnoticed |
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The adults of the dwarf tapeworm are |
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15 to 40 mm in length and 1 mm in width |
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The length of the adult T. solium is |
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Cysticercosis is an infection by the parasite |
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Taenia solium (pork tapeworm) |
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Cysticercosis is an infection by a parasite called Taenia solium , a pork tapeworm, that creates |
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cysts in different areas in the body |
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The larvae of T. solium are able to |
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invade tissue, and enter the bloodstream |
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Once The larvae of T. solium are able to invade tissue, and enter the bloodstream they are able to spread to many organs such as: |
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skeletal muscle, heart, eye, brain, and spinal cord |
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Taenia solium (pork tapeworm) form cysts in tissue called |
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cysticerci cannot grow into adult worms in this state, and remain |
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indefinitely encapsulated in tissue |
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An estimated __________ new cases of cysticerci are diagnosed per year in the United States |
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The length of the adult T. saginata is |
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Diphyllobothrium latum (fish tape worm)has a wide distribution, occurring especially in countries bordering the |
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Baltic Sea (Finland, Sweden and also in Russia, Switzerland and North America) |
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Diphyllobothrium latum (fish tape worm) is a problem in countries where the populations are known to eat |
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uncooked or partly cooked (i.e. smoked) fish |
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The fish tapeworm (Diphyllobothrium latum) can cause anemia because it |
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Vitamin B12 is necessary for |
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red blood cells to mature |
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Echinococcosis or Hydatid disease in man is caused by the |
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larval stage of the dog tapeworm, Echinococcus granulosus |
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Hydatid disease is most extensively found in |
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East Africa, North Africa, South Africa, the Middle East and parts of South America and Australia |
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Unilocular cyst of Echinococcus granulosus each enclosed in its own |
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Unilocular cyst of Echinococcus granulosus are called Hydatid cyst because |
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the whole being suspended in a hydatid fluid |
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Hydatid cyst in man give rise to |
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unilocular hydatid disease |
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Inside cyst in larva stage of E. Granulosus can’t mature in the |
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What are the organs that suffer in humans from Hydatid cyst |
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Prevention of Cestodes Infection: Taenia solium |
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cooking pork adequately and disposing of waste properly so that the pigs cann’t ingest human feces |
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Prevention of Cestodes Infection: Cysticerci |
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treatment of patient to prevent autoinfection plus observation of proper hygiene |
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Prevention of Cestodes Infection: Taenia saginata |
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Prevention involves cooking beef adequately and disposing of waste properly so that cattle cann’t consume human feces |
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Prevention of Cestodes Infection: Diphyllobothriasis |
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involves adequate cooking of fish and proper disposal of human feces |
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Prevention of Cestodes Infection: Hydatid cyst |
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involves not feeding the entrails of the slaughtered sheep to dogs |
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Diphyllobothrium Latum aka |
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Echinococcus granulosus aka |
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T. Solium, T. Saginata, & Diphyllobothrium latum all effect this site in the human body |
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T. Solium (cysticerci) effects these body parts |
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Echinococcus granulosus effects these body parts |
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Mode of transmission for T. Solium (A) |
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ingested larvae in undercooked pork |
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Mode of transmission for T. Solium (B)cysticerci |
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Ingested eggs in food or water contaminated with human feces |
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Mode of transmission for T. Saginata |
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ingested larvae in undercooked beef |
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Mode of transmission for Diphyllobothrium latum |
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ingested larvae in undercooked fish |
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Mode of transmission for Echinococcus granulosus |
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ingest eggs in food contaminated with dog feces |
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Diagnosis of T. Solium (A)& T. Saginata |
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Diagnosis of T. Solium (B)cysticerci |
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Diagnosis of Diphyllobothrium latum |
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operculated eggs in stool |
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Diagnosis of Echinococcus granulosus |
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Treatment for T. Solium, Diphyllobothrium latum, T. Saginata |
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Treatment for Echinococcus granulosus |
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Albendazole or surgical removal of cyst |
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Taenia Sginata (Beef tapeworm) |
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