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Micro Test 4
Chapt 21-26
118
Biology
Undergraduate 1
04/23/2011

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Term
This type of meningitis is caused by a small gram negative aerobic rod. It occurs primarily in children under the age of four.
Definition
Haemophilus influenzae meningitis
Term
Which type of meningitis was incorrectly identified as a cause for influenza
Definition
Haemophilus influenza meningitis
Term
Which type of menigitis has a carbohydrate capsule that aids in its survival
Definition
Haemophillus influenza meningitis
Term
Haemophilus influenza has what type of antigen that is most common in children where risk is high, but has nearly been eliminated by a vaccine
Definition
Antigen type B. HiB vaccine has almost eliminated it.
Term
When is the HiB vaccine usually given
Definition
6 months
Term
Which type of meningitis is caused by an aerobic gram negative cocci
Definition
Meningococcal menigitis(neisseria Meningitis)
Term
What is meningococcal menigitis synonymous with
Definition
neisseria menigitidis
Term
Which type of meningitis has a polysaccharide capsule that aids in virulence
Definition
Neisseria meningitis (Meningococcal meningitis)
Term
What percentage of the population constitutes the reservoir of infection
Definition
10%
Term
Where is Neisseria meningitis most common
Definition
In children under two, and sporadic adult cases associated with crowded stressful environments
Term
How many main capsule types are there for neisseria meningitis
Definition
five
Term
Is Meningococcal meningitis contagious
Definition
Highly
Term
What are common problems in survivors of neisseria meningitis
Definition
deafness or brain impariment
Term
What is the leading cause of bacterial meningitis
Definition
Streptococcal meningitis
Term
Which type of meningitis is caused by a gram positive encapsulated diplococci
Definition
streptococcal meningits
Term
What is the most common cause of strep pneumonia
Definition
streptococcus pneumoniae
Term
What are the mortality rates in children and in elderly adults who contract streptococcal meningitis
Definition
30% in children and 80% in elderly
Term
What causes tetanus
Definition
clostridium tetani
Term
Which microbe is a gram positive, spore forming, anaerobic rod common in soil and animal fecal waste
Definition
Clostridium tetani
Term
What are the symptoms of tetanus caused by
Definition
tetanus toxin which is also called tetanospasmin
Term
What is lockjaw
Definition
Tetanus
Term
How does tetanus happen
Definition
A deep puncture wound
Term
How does tetanus cause death
Definition
spastic paralysis and death by respiratory failure
Term
Is tetanus and infection or an intoxication
Definition
Both
Term
What percentage of adults and what percentage of children have good immunity to tetanus
Definition
96% children. 30% adults
Term
What can be administered to non-immune individuals following a severe wound
Definition
Tetanus Immune Globulin(TIG) prepared from the serum of immune individuals
Term
How often is a booster for tetanus vaccination required
Definition
Every 10 years
Term
What is the part of the DPT vaccine that immunizes against Tetanus
Definition
Tetanus toxoid(inactive toxin)
Term
What is botulism
Definition
a potentially deadly form of food poisoning
Term
What are five virulence determinants for S. aureus
Definition
resists phagocytosis, immobilize neutrophils, induces vomiting and diarrhea, form clots, kills phagocytosis
Term
What is TSS caused by
Definition
Toxin 1
Term
what disease is caused by bullous impetigo
Definition
Scladed skin syndrome
Term
which family of streptococcal pathogens is alpha hemolytic
Definition
strep pnuemoniea
Term
What are two characteristics of S. pyogenes
Definition
B hemolytic strep, divided into 80 antigenic types based on M protein
Term
What is M protein involved in
Definition
attachment, phagocytic avoidance, and compliment activation.
Term
degrades connective tissue
Definition
hyaluronidase
Term
streptokinases do
Definition
dissolve blood clots
Term
which disease is caused by GAS infection of the dermal layer of skin. preceded by GAS sore throat
Definition
eresypelas
Term
How is erisypelas is treated with what
Definition
B-lactam antibiotics
Term
What is necrotizing fasciitis caused by
Definition
invasive strains of GAS
Term
What is the key to the destruction in necrotizing fasciitis
Definition
exotoxin A
Term
where is psuedomonas normally found? what are some characteristics of it
Definition
soil and water. aerobic gram negative rod
Term
what is the most common skin infection
Definition
acne
Term
how is comedonal acne caused
Definition
shedding skin cells mixed with sebum clog follicles
Term
What causes inflammatory acne
Definition
propionibacterium acnes (aerobic diptheroid)
Term
Which kind of acne leads to scaring
Definition
nodular or cystic
Term
what is caused by papillomas
Definition
warts
Term
what are papillomas
Definition
benign skin growths caused by viruses
Term
Variolla
Definition
small pox
Term
whatis the mortality rate of variolla major vs mino
Definition
major 20% minor 1%
Term
When did variolla minor appear
Definition
1900
Term
How is small pox transmitted
Definition
respiratory route
Term
what was the first disease with artificialy induced immunity
Definition
small pox
Term
what is the cause of chicken pox
Definition
Varicella zoster, HHV3
Term
How is chicken pox acquired
Definition
deposition in nasopharynx or inhalation.
Term
when is chicken pox fatal
Definition
When it is acquired in early pregnancy
Term
What does varicella zoster reamerge as
Definition
shingles
Term
What percentage of us population is infected with HSV 1
Definition
90%
Term
what disease is rare but can be caused by HSV 1 or 2
Definition
Herpes Encephalitis
Term
What disease is caused by parymoxyviridae
Definition
measles
Term
what is rubeolla
Definition
measles
Term
How is measles spread
Definition
droplet contact from nose or mouth
Term
Who is measles most fatal for
Definition
children <1
Term
rare measles complication
Definition
subacute sclerosing panencephalitis
Term
german measles is caused by
Definition
rubella
Term
which is worse rubella or rubeolla
Definition
rubeolla
Term
what is the situation that makes rubella have a 35% chance of fetal damage
Definition
contraction of the mother in the first trimester
Term
what are the three fungi genera that are responsible for cutaneous mycoses
Definition
trichophyton, microsporum, and epidermophyton
Term
what is a KOH test used to diagnose
Definition
cutaneous mycoses
Term
tinea capitis
Definition
ringworm of the scalp
Term
tinea pedis
Definition
athletes foot
Term
Jock itch
Definition
tinea cruris
Term
what can grow on the keratin layer of skin
Definition
dermatophytes
Term
What disease is caused by an obligate anaerobic gram positive, spore forming, rod shaped bacterium which is often found is soil and water sediments
Definition
botulism
Term
What is the microbe that causes botulism
Definition
Clostridium botulinum and botulism toxin which is the product
Term
What are symptoms of botulism
Definition
slurred speech, blurred vision, and paralysis
Term
What neurotoxin associated with botulism is deadly and causes flaccid paralysis; death by respiratory failure
Definition
Neurotoxin A
Term
What disease is the best known cause of paralysis
Definition
poiliomyelitis
Term
What disease first appeared in the US in 1894 with an outbreak in Vermont
Definition
Polio
Term
What season is associated with polio
Definition
summer
Term
How is death caused in polio
Definition
respiratory failure
Term
How is polio transmitted
Definition
contaminated water
Term
How does polio cause paralysis
Definition
invasion of the tonsils and small intestine by the virus lead to involvement of the lymphatic system and blood stream. Viremia leads to invasion of capillary walls and CNS involvment where it infects the motor nerve cells of the CNS, the cells die, and paralysis results
Term
Global effort to eradicate what disease started in 1988
Definition
Polio
Term
what is OPV
Definition
oral polio vaccine
Term
Sabin vaccine introduced in 1963 was for what disease and it contained what
Definition
It was for polio and it contained three living attenuated virus strains. Single dose vaccine
Term
Which disease is caused by a neurotrophic virus which is single stranded RNA with no proofreading capabilities
Definition
Rabies
Term
How do humans get rabies
Definition
by the bite of an infected animal
Term
What is the most common cause of rabies in the US
Definition
silver haired bad(dogs have a high immunization rate)
Term
How does the rabies virus work?
Definition
the virus replicates in epidermal cells; can also multiply in the muscle and connective tissue. then enters peripheral nervous system and travels along peripheral nerves at a rate of 15-100mm/day. Once it is in the CNS causes encephalitis and is inaccessible to the immune system as the CNS begins to be destroyed.
Term
What disease allows for post exposure immunization
Definition
rabies
Term
What happens to a patient with rabies when the CNS begins to get involved
Definition
aggitation mixed with intervals of calm
Term
what disease is also called hydrophobia and why
Definition
rabies; muscle spasm in mouth and pharynx especially when swallowing liquids.
Term
how is rabies prevented
Definition
vaccine. Vets and animal control individuals are also immunized
Term
what is post exposure prophylaxis
Definition
series of anti-rabies vaccine and immune globulin injections given if a person is bitten and the animal is positive for rabies
Term
What is the trilaminar membrane system that protects the brain and spinal cord
Definition
meninges
Term
What is the restrictive capillary system that protects the brain and spinal column from invasion by potentially toxic compounds and microbes
Definition
Blood Brain Barrier
Term
What are the diseases that we discussed that are diseases of the CNS or diseases that affect the CNS
Definition
Meningitis(Haemophilus, Neisseria, Streptococcal), Tetanus, Botulism, Poliomyelitis, rabies
Term
What are all the nerves that branch off from the brain and spinal cord
Definition
Peripheral Nervous System
Term
What is the brain and spinal cord collectively called
Definition
Central Nervous System
Term
What holds cerebrospinal fluid
Definition
subarachnoid space
Term
What disease has symptoms including, fever, headache, and a stiff neck, often followed by nausea and vomiting, convulsions, and coma
Definition
Bacterial meningitis
Term
What is asceptic meningitis
Definition
Viral meningitis
Term
Which is more pathogenic viral or bacterial meningitis? Which one is more common
Definition
Bacterial is more pathogenic and deadly, and viral is more common
Term
How is the antibody given with bacterial meningitis
Definition
Intravenously
Term
Where is H influenzae found commonly
Definition
throat flora, especially in children
Term
By age five children are typically immune to what disease due to cross immunity to other agents
Definition
Haemophilus influenzae meningitis
Term
Neisseria meningitidis is what shape
Definition
cocci
Term
Haemophilus influenzae is what shape
Definition
rod
Term
Which type of meningitis what described as very invasive
Definition
Neisseria meningitis
Term
What type of meningitis typically starts with pneumonia or otitis media and progresses from there
Definition
streptococcal meningitis which is caused by streptococcus pneumoniae
Term
What shape is streptococcus pneumoniae
Definition
diplococci
Term
Which type of meningitis is caused by a gram positive microbe
Definition
streptococcal meningitis
Term
How are botulism and tetanus different? How are they similar
Definition
Both are diseases of the CNS. Both are gram positive, obligate anaerobes, spore forming, rods. Botulism is a food poisoning(intoxication from type A neurotoxin) and tetanus is from puncture wounds(tetanus toxin).
Term
What percentage of people who get polio become paralyzed
Definition
1% of all those infected with the virus
Term
What is the salk vaccine
Definition
A vaccine for polio developed in 1954. It was 90% effective and required a series of injections
Term
Rabies virus is what type of virus
Definition
Neurotropic
Term
In the final stages of this neurotropic viral disease there is extensive damage to nerve cells of the brain and spinal cord.
Definition
rabies
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