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Micro Helminths
KYCOM Block 9
59
Microbiology
Graduate
08/31/2013

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Term
neglected infection
Definition
gets little attentio, survelence, prevention, and treatment
Term
helminth aka
Definition
worms
Term
helminth transmission
Definition
egg or larvae form
fecal oral
ingestion
penetration of skin
vector
Term
types of hosts
Definition
difinitive: site of replication
intermediate: site of replacion in a transfer host
accidential: not the usual host
Term
endoparasite
Definition
inside host / cell
Term
exoparasite
Definition
outside the host (skin) / outside cell
Term
what areas or people are more likley to be infected with a helminth
Definition
subtropic or tropic areas
children
people who work animals
people who work with food
poor sanatation
Term
what are the forms of reproduction in helminths
Definition
sexual: egg is in feces and matures in next host or builds up in intestines

asexual: not as common
Term
what types of defenses do helminths have against the immune system
Definition
cyst or egg in cell wall (innate avoidance)

antigenic varation, mollecular miciry

hide intracellularly
Term
define carrier
Definition
harbors parasite, no symptoms
Term
define vector
Definition
transports parasite via fecal oral or penentration, etc
Term
define indirect life cycle
Definition
reproductive stanges must undergo further development in intermediate host or vector before sexual maturity in final host
Term
define trophozoite
Definition
active feeding protozoa
Term
define cyst
Definition
inactive ineffective ptotoza
Term
define hydadid cyst, who has one
Definition
infective stage of a e. granulosus
Term
fluke aka
Definition
termatode, paragonimus, digenea, platyhelminth, flat worm
Term
defining characteristcs of a fluke (eating, composition, virulence)
Definition
muscular suckers and hooks for host attachment
surface is a complex plasma membrane with protective mechanisms
feed on host tissue of intestine content
Term
life cycle of a fluke: infectve stage, reproduction
Definition
indirect life cycle: intermetidate hosts needed
metcercaria: infectve stage
mature in intestines, lungs, liver, vessels
mostly hermaphodytes
Term
give three examples of flukes
Definition
clonorchis
schistomes
F. bushki
Term
where is clonorchis found. what is it
Definition
tissues, fluke flat worm
Term
schistosomes: virulence factor, reproduction
Definition
acquire host molecules to disguise from immune system
blood flukes: in vessel and tissue
not hemaphodytes
part of life in snail
Term
schistosomes: life cycle
Definition
eggs hatch and release miracidia which penentrates snail
develop into sporocyst in snail
release into water as cerariae (infective stage)
penetrates human skin or drank
loses tail and becomes schistosomulae
enters circulation and go to liver to mature
goes to bladder/bowel and has sex
lays eggs
Term
what is the clinical sign in humans of schistosomes
Definition
hypersenstivity to the eggs as they pass through the tissues
schistosomiasis disease
Term
F. bushki: classification, location, appearance
Definition
endemic
sheep liver tissue fluke
flattened leaf structure
in water chesnuts and bamboo
Term
F. bushki: how it infects, clinical signs
Definition
eaten via water chesnut or babmoo
attaches to wall of SI

obstruction, malasborption, diarrhea, anorexia, acities
eosinophillia
Term
round worms aka
Definition
nematodes
Term
round worm: descibe what they look like, how they eat, antigenic parts, what they infect
Definition
long cilldrical body with no attachment organs

feed on host tissues and intestine content

outer collagenous cutile that is antigenic but resistant to attack

mostly human specific but some are zoonoses (human can be the intermediate)
Term
in what ways does a round worm reproduce (3 facts)
Definition
common: seperate sexes lay fertizied eggs

less common: autoinfection, eggs made in intestins can reproducte and re-infect

direct and indirect development
Term
how are nematodes separated into categories
Definition
those that mature in the GI tract
those that mature in deep tissues
Term
what are 4 examples of round worms
Definition
a. lumbracoides
hookworms
srongglides
Loa Loa
Term
loa loa: where does it infect, what are the symptoms
Definition
adult is in subcutaneous tissue causing local pain and swelling

larvae migrate to the conjunctiva and cause calabar swelling (below the eye)
Term
how is stronglide tested for, what other oragnism is tested for in the same way
Definition
use enterotest on the duodenal sample

giardia too
Term
tapeworms aka
Definition
cestodes, flat worms, platyhelminth
Term
tapeworm: describe body, how does it eat
Definition
muscular sucker and hooks for host attach

complex plasmam membrane with protective mechanisms to prevent host damage

no digestive system and absorb pre-digested nutrients
Term
how do you catch a tapeworm, what do they do to people
Definition
eat undercooked meat with larva in it
relativly harmless unless they get to big or are an intermediate host for other species
Term
explain the life cycle of a tapeworm
Definition
egg in feces > enivornment > eaten by pig > onocsphere hatch > pig circulation > muscle and tissue > cysteri (inactive) > humans eat undercooked pig > scolex attaches to intestine and grows > lays eggs > poo them
Term
what is an example of a tapeworm in an accidental host
Definition
if the eggs in feces are eaten by human and skip the pig stage it can develop into oncosphere in human and go into muscle and tissue

only with Tanea solium
Term
tapeworm reproduction: what are the reproductive parts of a tapeworm
Definition
strobila: reproductive organs, along body segments

proglottids: segments of reproductive organs

gravid: terminal proglodid that become filled with eggs
Term
how do tapeworms usually reproduction, what is the exception
Definition
autoinfection: egg hatches in humand and re-infects human

sexual reproduction: eggs released in feces or accumulate in host

indirect reproduction: development in intermediate host for maturing

exception: H. nana non-indirect. comes directly from arthropod
Term
give 3 examples of tapeworms
Definition
tanea saginata
taenia solium
E. granulosus
Term
where does E. granulosus infect
Definition
GI, liver, lungs, brain
Term
what are the three types of arthropods, what characteristics define arthropids
Definition
insects, arachnids, crustaceans
exoskeleton, jointed apendages
Term
how do arachnids transfer infection
Definition
mechanical: feces or contaminated soil to food

biological: blood meal
Term
what are the types of arthropods by feeding
Definition
blood feeders: mosquitoes, midges, bitiing flies, bugs, fleas, ticks

mites: chiggers, scabes

ectoparasites: lice, fleas, ticks, bot flies
Term
what are the types of arthropods by type of contact
Definition
temporary: mosquito, tick

permanent: louse, scabies
Term
what are the types of mosquitos, give an example of a disease they transfer
Definition
ades: encephalitis, yellow fever, dengue

anopheles: malaria, encephalitis

culex and mansonia: encephalitis
Term
what are the types of ticks, what diseases do they carry
Definition
dermacentor: RMSF, q fever, colorado tick fever

loxodes: babesia, colorodo tick fever

ornithodoros: norrelia hermasi
Term
what are the types of biting flies what type of disease do they transmit
Definition
black: onchocerciasis
phlebotomus: leishmania
crysops: loa loa
tsetse: t. brucei
domestic, screw, bot: myiasis (maggots)
Term
how do bed bugs function, why do they do to people
Definition
noctournal blood feders
causes allergic reaction to their saliva
Term
what transmits T. crusi
Definition
kissing, redubiid, assassin bug
Term
what diseases does a flea transfer
Definition
rickettsia, H. nana, caninum, typhoid, Y. pestis (plague)
Term
what are the types of lice, what do they transmid
Definition
pediculus humanus (body): relapsing fever, epidemia typhus, tranch fever

peridulus capitus (head)
Term
what is the science name for crabs. where can it be located
Definition
phthirus pubis

pubic hair, beard, mustache, armpit, eyebrows, eyelash
Term
what problems does a bee sting case
Definition
allergic reaction bua hemolyzing factor, histamine, epinepherine, anti-histamine
Term
what does black widdow toxin do
Definition
neurotoxin causes abdominal cramps, hypertension, shock
usually not fatal
Term
what does a brown recluse toxin do
Definition
necrotizing wound
larger dose more fatal
Term
what does a scorpion toxin do
Definition
neurotoxin worse in kids and eldery

pain, muscle spasm, respiratory paralysis
Term
what is another name for scabbes, how does it work
Definition
sarcoptes scanei (skin mange)
female burrows into skin and lays eggs
larvae migrates through upper skin layer
Term
filariasis: what is it, where is it located, what does it do
Definition
arthropod vector
comes from bancroft or brugia malayi
blocks lymph ducts by adults causing lymphadenitis, orchitis, elephantitis
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