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Micro Exam 2 Chapter 11
mutations and genetics of bacteria
26
Microbiology
Not Applicable
10/04/2021

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Term
mutation
Definition
a heritable change that is passed from the mother cell to progeny cells
Term
genotype
Definition
nucleotide sequence of a genome, complete genetic makeup
Term
phenotype
Definition
observable properties of a mutant
Term
wild type strain
Definition
a strain of an organism or virus isolated from nature
Term
mutant
Definition
cell or virus derived from wild type that carries a change in nucleotide sequence
Term
spontaneous mutation
Definition
mutations that occur without external intervention; usually results in errors from base pairing
Term
induced mutation
Definition
caused by agents in the environment including those induced by humans
Term
mutagen
Definition
an agent that causes genetic mutation
Term
missense mutation
Definition
change in the first or second base of the codon leading to significant changes in the amino acid sequence of the polypeptide
Term
nonsense mutation
Definition
formation of a stop codon leading to premature termination of translation leading to an incomplete polypeptide
Term
silent mutation
Definition
changes in DNA that do not affect the polypeptide
Term
frameshift mutation
Definition
insertion or deletion of a single base pair resulting in a shift in the reading
Term
vertical gene transfer
Definition
the transmission of genetic information from one generation to the next generation
Term
genetic diversity
Definition
in sexually reproducing organisms, ___________ is achieved by sexual reproduction, gene mixing, or mutation
Term
identical copy
Definition
produced by asexual reproduction
Term
horizontal gene transfer
Definition
introduction if genetic material from one generation to another organism within the same generation
Term
transformation
Definition
horizontal genetic transfer process which involves the direct uptake of DNA from environment
Term
conjugation
Definition
DNA is directly transferred by a sex pilus and located on the F plasmid known as the fertility factor
Term
F+ donor cell
Definition
cells containing the F plasmid
Term
F- recipient cell
Definition
cells lacking an F plasmid
Term
R plasmid
Definition
antibiotic resistance in a cell
Term
transposition
Definition
DNA molecules that have inverted repeat sequences at their ends and a gene encoding and enzyme; known at the jumping genes; originally discovered in maize
Term
competent cells
Definition
bacterial cells capable of transformation
Term
transduction
Definition
occurs when a bacteriophage transfers bacterial DNA from one bacterium to another; generalized or specialized
Term
generalized
Definition
transduction that takes place during the lytic cycle where bacterial DNA is absorbed by a virus
Term
specialized
Definition
transduction that takes place at the end of the lysogenic cycle when the provirus is induced to get excised
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