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Micro Exam 2 Chapter 10
Viral genomes, diversity, and ecology
20
Microbiology
Not Applicable
10/04/2021

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Term
Baltimore classification
Definition
most commonly used system of virus classification by David Biltmore ex. dsDNA, ssDNA
Term
dsDNA
Definition
mRNA in transcribed directly from DNA ex. herpesvirus
Term
ssDNA
Definition
DNA is converted to double stranded form before RNA is transcribed ex. parvovirus
Term
dsRNA
Definition
mRNA is transcribed from the RNA genome ex. rotavirus
Term
ssRNA+
Definition
genome functions as mRNA ex. picornavirus
Term
ssRNA-
Definition
mRNA is transcribed from the RNA genome ex. rabies (rhabdovirus)
Term
ssRNA with reverse transcriptase
Definition
reverse transcriptase makes DNA from the RNA genome, DNA is incorporated into host, mRNA is transcribed from incorporated DNA ex. HIV
Term
dsDNA with reverse transcriptase
Definition
double stranded DNA, but viral DNA is replicated through and RNA intermediate ex. hepatitis B virus
Term
oncogenic virus
Definition
viruses that introduce genes that cause uncontrolled growth of cells called oncogenes and interfere with expression of genes that control cell division ex. HPV -> cervical cancer
Term
influenza virus
Definition
causes the highly infectious airborne disease; contains 8 segments of RNA surrounded by an envelope and external antigen receptors
Term
hemagglutinin (HA)
Definition
glycoprotein on surface of influenza - 17 variations; helps virus attach to silica acid to facilitate entry into host cell
Term
neuraminidase
Definition
glycoprotein on surface of influenza A - 10 variations; helps the viral progenies excise from human cell and exit the host cell
Term
H1N1 virus
Definition
extremely infectious virus due to transmissible antigens
Term
cytokines
Definition
produced by white blood cells to fight virus and increases temperature
Term
antigenic drift
Definition
happens when mutations take place in genes encoding for HA and NA antigens diminishing host immunity to a virus - reason why new vaccines are needed yearly
Term
antigenic shift
Definition
happens when an organism is infected with two viruses at the same time resulting in a mixing of genes called gene reassortment; H1N1 happened due to this
Term
viroid
Definition
single strand circular RNA molecules that mostly infects plants and range in size 250-400 nucleotides ex, potato spindle tuber
Term
prion
Definition
lack DNA and RNA and consists primarily of proteins, spreads due to consuming meat from your own species
Term
Kuru
Definition
neurodegenerative disease that causes shaking, loss of motor control, and outburst of laughter followed by death; found in humans; discovered in Papua New Guinea
Term
BSE (bovine spongiform encephalopathy)
Definition
"mad cow disease"
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