Term
| Pathogenic Properties of Bacteria |
|
Definition
- exotoxins
- endotoxins
- adhesins and pili
- capsules
- cytotoxins
- enzymes |
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Term
|
Definition
- requires receptor and adhesin
- allows bacteria to adhere to host cell |
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Term
|
Definition
- protein
- often associated with pili or flagella
- may be associated with capsule |
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Term
|
Definition
| - carbohydrates on eukaryotic cell surface |
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Term
| Viral Attachment Proteins (VAP) |
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Definition
| - peplomers of envelope or capsid attaches a virus to bacterial pellicle of tooth |
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Term
|
Definition
- ability of the microorganism to invade human tissue
- aided by enzymes/exoenzymes and invasins |
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Term
|
Definition
- an exoenzyme
- breaks down cell cement (hyaluronic acid) to invade tissue |
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Term
|
Definition
| - lyse blood clot (fibrin) |
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Term
|
Definition
| - protect invaders from phagocytosis |
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Term
|
Definition
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Term
|
Definition
- also called capsule
- bacterial surface coating
- usually carbs
- convey antiphagocytic properties to cell
- antigenic
- hydrophilic, gel-like |
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Term
|
Definition
| - bacteria and glycocalyx |
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|
Term
| Bacillus anthracis capsule |
|
Definition
| - rare protein glycocalyx |
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Term
|
Definition
- lipolysaccharide
- less potent but stable to heating
- g(-) |
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|
Term
| biological activity of endotoxin |
|
Definition
- general physiological effects
- fever, Intravascular coagulation, leukopenia, activation of comlement
- shock and death |
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Term
|
Definition
| - lipid a responsible for toxicity |
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Term
|
Definition
- released extracellularly
- g(+) and g(-)
- proteins
- highly toxic |
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|
Term
| biologic activity of exotoxins |
|
Definition
- inhibition of protein synthesis, cytotoxic, neurotoxic
- target specific organs |
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Term
|
Definition
| - two parts to exotoxins and enterotoxins |
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Term
|
Definition
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Term
|
Definition
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Term
|
Definition
- kill cells
- block protein synthesis (stop cell metabolism)
- interfere with cellular functions
- disrupt cell membrane |
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Term
|
Definition
- block protein synthesis
- block airway by forming pseudomembrane in throat |
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Term
|
Definition
- intestinal inflammation
- loss of water/ions
- diarrhea
- blocks function of enzymes
- also bipartite toxins |
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Term
|
Definition
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Term
|
Definition
- most potent toxin known
- suppresses release of ACH
- death due to paralysis of respiratory muscles
-improperly canned food |
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Term
|
Definition
- blocks synaptic inhibition
- muscle spasms --> spastic paralysis |
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Term
|
Definition
- stimulate T cells to release cytokines
- toxic shock syndrome |
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|
Term
| other cell wall components |
|
Definition
- peptidoglycan
- teichoic and lipoteichoic acids |
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Term
|
Definition
- stimulate toxin-like pyrogenic acute phase responses
- like endotoxin
- inflammation |
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