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micro chap 13&20
micro test
17
Microbiology
Undergraduate 1
10/30/2014

Additional Microbiology Flashcards

 


 

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Term
viruses are entities that
Definition
-Contain a single type of nucleic acid, either DNA or RNA [never both].
-Contain a protein coat (sometimes itself enclosed by an envelope of lipids, proteins, and carbohydrates) that surrounds the nucleic acid.
-Multiply inside living cells by using the synthesizing machinery of the cell.
-Cause the synthesis of specialized structures that can transfer the viral nucleic acid to other cells.
Term
viruses must be grown in
Definition
living cells
Term
attachment
Definition
phage attaches by tail fibers to host cells
Term
penetration
Definition
phage lysozyme opens cell wall, tail sheath contracts to force tail core and DNA into cell
Term
Biosynthesis
Definition
Production of phage DNA and proteins
Term
Maturation
Definition
Assembly of phage particles
Term
Release
Definition
Phage lysozyme breaks cell wall
Term
Prion = proteinaceous infections particle
Definition
Disease caused by conversion of normal protein into an infectious form (mechanism unclear)
Term
Chemotherapy
Definition
The use of drugs to treat a disease
Term
Antimicrobial drugs
Definition
Interfere with the growth of microbes within a host
Term
Antibiotic
Definition
Substance produced by a microbe that, in small amounts, inhibits another microbe
Term
Selective toxicity
Definition
A drug that kills harmful microbes without damaging the host
Term
Broad-spectrum drug
Definition
an antibiotic that is effective against a wide range of both gram-positive and gram-negative bacteria.
Term
Mechanisms of antibiotic resistance:
Definition
1. Enzymatic destruction of drug
2.Prevention of penetration of drug
3.Alteration of drug's target site
4. Rapid ejection of the drug
Term
Misuse of antibiotics selects for resistance mutants. Misuse includes:
Definition
-Using outdated, weakened antibiotics
-Using antibiotics for the common cold and other inappropriate conditions
-Use of antibiotics in animal feed
Failure to complete the prescribed regimen
-Using someone else's leftover prescription
Term
Synergism
Definition
occurs when the effect of two drugs together is greater than the effect of either alone.
Term
Antagonism
Definition
occurs when the effect of two drugs together is less than the effect of either alone.
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