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Formed by protozoa under adverse conditions. Round or oval protective coating. Allows survival until conditions improve. Latent form. |
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Naegleria spp, Naegleria fowleri |
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"Brain Eating Amoeba" Water containing the amoeba get high into the nose, bind to olfactory nerve gaining access to the brain. Risk factors: swimming, diving, splashing in warm bodies of standing water. |
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Unresolved may lead to chronic granulomatous encephalitis (inflamation of the brain). Corneal ulceration leading to blindness may also occur |
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Pathogenic
Highest rates in areas of crowding and poor sanitation
10% of worlds population
Perforation of amoebic ulcers facilitate invasion of deeper tissue
Abscess formation may occur
Fecal oral |
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Active form of protozoa. Not in cyst form. |
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Host carries the organism, but with no symptoms; can spread to others. |
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Urogenital flagellate
Trophozoite stage only
Infection by sexual intercourse or fomites
Sympromatic women: scant watery discharge, painful urination
Symptomatic men: urethritis and prostatitis |
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inanimate object that spreads disease |
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Most common pathogen in US drinking water.
Intestinal flagellates
Has a "looking back" apearance
Cyst is resistant to standard chlorine concentrations, can be removed through filtration. |
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Cause: Giardia lamblia
AKA Bever Fever
Diarrhea, flatulence, abdominal pains, fatty stools |
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tiny form of trypanosome, becomes bigger in the body |
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Trypanosoma brucei gambiense |
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Definition
Classic African Sleeping Sickness
Transmitted by the tsetse fly |
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Classic African Sleeping Sickness |
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Definition
Caused by Trypanasoma brucei gambiense
asymptomatic incubation period lasting a few weeks to several months. Neurological stage 7-8 year process. |
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Trypanosoma brucei rhodesiense |
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Definition
more virulent form of trypanosomiasis Vector: teste fly
Untreated death within 9-12 months
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Definition
causes chaga's disease (American trypanosomiasis)
Transmited by the reduviid (kissing)bug
Resevoir: wild rodents, armadillos
Causes IgM levels to rise
Cardiac muscle where amastigotes proliferat atrophy |
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Transmitted by the sand fly |
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most common malarial parasite
Invades reticulocytes (young RBC's)
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Also attacks reticulocytes. |
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Much lower incidence Attacks mature RBC's |
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infectious form of malaria from a mosquito |
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worst form of malaria Targets all stages of RBC's Causes blood in the urine, gives severe malaria the name blackwater fever. |
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Up to 80% of individuals in some populations carry the disease. estimated 1/3 of the world population
Definitive host is the domestic cat
3 days for oocysts to mature
Infection results from ingestion of oocysts
Sex cycle occurs only in feline intestinal tract
Infection usually occurs after contact with litter/sand box, gardening, playing with cat poo
Immune system encysts the paracite, typically do not reemerge
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serum IgE levels rise during parasitic infection. useful in diagnosing infection. |
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Flukes
Flat, fleshy, leaf shaped body Hermaphroditic (except for Shistosomes) |
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Liver Fluke
Infection from ingestion of raw/undercooked fish.
Resevoirs: Raw fish-eating mammals |
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Giant intestinal fluke
Resevoir hosts: pigs, dogs, rabits |
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infective encysted larval stage of fluke |
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Lung fluke Eggs are discharged into the bronchi or bronchioles, later apearing in feces or sputum Often misdiagnosed as TB |
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Blood Flukes Non hermaphroditic Infection does not result from ingestion |
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Eggs deposited in bladder wall, may break through into the lumen and escape with the urine. Feared as male menstruation |
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Non-human pathogenic schistosomes |
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Schistosomal dermatitis AKA swimmers itch |
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attachment organ of a tapeworm. If it remains the worm will regrow |
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body segments of a tapeworm, a chain of proglottids is called a strobila |
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Pork tapeworm Aquired by ingestin the larval form (cysticercus AKA bladder worm) There may be a second stage of infection. |
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socond stage of infection by pork tapeworm. Ingested eggs travel to duodenum where they hatch and penetrate the intestinal wall. |
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The minute tapeworm Causes hydatid disease Found in sheep |
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Dwarf tapeworm common parasite of house mouse Can be found in grains. Eggs from adult worm may hatch in hosts intestine and cause second generation infection. |
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broad fish tapeworm longest human tapeworm Causes normochromatic macrocytic anemia due to absorption of B12 |
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Phylum: Aschelminthes Roundworms covered by tough protective covering (cuticle) Have complete digestive tract sexes are seperate |
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Large intestinal round worm Found in areas of poor sanitation Eggs are ingested Larva penetrate wall of duodenum, enter blood or lymphatic vessels. grow and molt in lungs. mature in intestines. |
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Pin worm Most common helminth in sanitary areas No symptoms in carriers Female explodes outside anus releasing eggs and causing itch. |
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Caused by Entamoeba histolitica
Most cosmopolotan parasitic diseas |
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Caused by Entamoeba histolytica
AKA amoebic dysentery
bloody, slimy, and unusually smelly diarrhea |
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Extraintestinal amoebiasis |
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Definition
Caused by Entamoeba histolytica
Infection of the liver is common |
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Hemoflagellates
live in the blood, between cells but not in them |
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Characteristic of Gambian "classic" Sleeping sickness
Swelling of the posterior cervical lymph nodes |
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Toxo
Caused by toxoplasma gondii
Fetus is particularly susceptible especially during third trimester.
Symptoms for neonatal: convulsions, retardation
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Trematode larva
Typically infect snails |
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Strongyloides stercoralis |
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Definition
Threadworm can exist as a free-living nematode larva penetrate the skin, migrate through the lungs, and reach small intestine. "showers of worms" in feces Auto infection-multiple life cycles in host |
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infectious hookworm larva |
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non-infectious nematode larva |
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Two species are human pathogens No intermediates or resevoir hosts |
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Old World Hookworm larva enter cutaneous venules, passively carried to lungs, break into alveoli. Migrate to trachea and are swallowed Induce Microcytic Hypochromic Anemia suck blood and tissue fluids |
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New World Hookworm only hookworm in N. America produces "ground itch" where entering skin |
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Ancylostoma braziliense or caninum |
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Dog hookworms Will penetrate skin and cause itching. Survive weeks just below surface, then die. |
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live births parisite of carniverous mammals Larva encyst in muscle tissue |
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Live births thread like nematodes live in various locations Not diagnosed by eggs in feces (live birth) |
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a filiariae Spread by mosquitoes Mature in lymph nodes produce microfilariae dead worms cause alergic reactions
Causes Filariasis |
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caused by wuchereria bancrofti Febrile attacks reffered to as elephantoid fever Lymphangitis and Elephantiasis-does not occur in all infested individuals |
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African eye worm Resevoir: Monkeys Vector: Mango fly no lasting damage to host |
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causes River Blindness Vector: Black fly or Buffalo gnat |
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the Guinea Worm Not a true filaria Ingestion of larva in water females migrate to subcutaneous tissue |
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