Term
|
Definition
| virulence factors that damage the host |
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Term
|
Definition
| Lipid A portion of lipopolysaccharide |
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Term
|
Definition
that it's secreted
OR released with cell lysis |
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Term
|
Definition
| cause diarrhea or vomiting |
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Term
| Shiga-like toxin aka _ is from _ |
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Definition
|
|
Term
| pseudomonas aeruginosa features toxin: |
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Definition
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Term
| A-B toxins. A is _ B is _. B is often made of _ but sometimes _ |
|
Definition
enzymatic ("Active")
binding
carbohydrate; protein |
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|
Term
| A-B toxins may be _ or _ (2 classes) |
|
Definition
|
|
Term
| translocation of A-B toxins can be by 2 ways |
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Definition
|
|
Term
| many A-B toxins have a _ mechanism |
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Definition
| ADP-ribosylation of a host cell protein |
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Term
| membrane-disrupting toxins 2 types |
|
Definition
pore forming
phospholipases |
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Term
| (2) examples of pore-forming toxins |
|
Definition
alpha-haemolysin
Panton-Valentine leukocidin (necrotizing factor) |
|
|
Term
example of phospholipase _ toxin:
in what bacterium? |
|
Definition
| clostridium perfringens alpha toxin (phospholipase C) |
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|
Term
| superantigens massively stimulate _ to make _. may result in (2) |
|
Definition
T cells
cytokines
fever
shock |
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Term
|
Definition
form a bridge between MHC class II of Ag-presenting cells
and T cell receptors |
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|
Term
| 2 bacteria that cause toxic shock syndrome |
|
Definition
staphylococcus aureus
strep pyogenes |
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|
Term
| toxic shock syndrome is caused by what kind of toxin? |
|
Definition
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|
Term
| 2 examples of food poisoning |
|
Definition
-(SEA Staph enterotoxin A) by staph aureus
-botulinum toxin |
|
|
Term
| 3 groups of toxins roles in disease |
|
Definition
-food poisoning (e.g. SEA; botulism)
-colonize a surface and toxins act locally (cholera) or invade bloodstream (diphtheria)
-local tissue damage in abscesses (clostridium perfringens) |
|
|
Term
| clostridum perfringens _ toxin facilitates bacterial _ |
|
Definition
|
|
Term
| alpha toxin is in what bacterium |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
| Panton-Valenine leukocidin |
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|
