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Micro Anatomy Digestive System
Exam 2 digestive system
95
Histology
Professional
03/21/2012

Additional Histology Flashcards

 


 

Cards

Term

keratinized oral mucosa

hint: what contacts food and friction?

Definition

dental pad

dorsal surface of tongue

hard palate

cheek

Term
orbicularis oris
Definition
lip skeletal muscle
Term
mucocutaneous junction
Definition
on lip, area where musocal surface meets outer lip surface
Term
 papillae with mechanical function 
Definition
filiform
Term
papillae with sensory function
Definition

Vallate / Circumvallate

fungiform

foliate

Term
filiform papillae
Definition

most common type

slender conical projections

bristles, can be rougher in some species

Term
circumvallate (vallate) papillae
Definition

least numerous type

short broad CT stalk with nerves

taste buds along sides

does not protrude above surface - surrounded by moat

back of tongue

Term
fungiform papillae
Definition

mushroom shaped

CT core
rise higer than filiform 

 

Term
foliate papillae
Definition

flat topped / square shape

deep clefts between

important in lagomorphs (rabbit)

lots of taste buds

Term
taste buds
Definition

encapsulated by thin CT

light stain with darker sensory cells

taste pore: break in epithelium

Term
gingiva
Definition

should just be epithelium and lamina propria

keratinizing stratified squamous epithelium

lamina propria shouldn't take up too much - hyperplasia

Term
palate
Definition

hard with bone, soft without

oral surface: stratified squamous epithelium

respiratory nasal surface: cilitated columnar

Term
ameloblasts
Definition
produce enamel
Term
odontoblasts
Definition
produce dentin
Term
periodontal ligament
Definition
anchors tooth to alveolar bone
Term
pulp cavity
Definition
living tissue including blood vessels and mesenchyme
Term
alveolar bone
Definition
sockets in jaw for teeth
Term
enamel
Definition

outer covering of tooth

crowns

not visible in slides - lost in processing

Term
dentin
Definition

major bulk of the tooth

softer than enamel

Term
cementum
Definition

bone like substance

covers tooth root - does not protrude beyond gum line

Term
brachydont teeth
Definition

enamel is made up until teeth erupt

after eruption ameloblasts die

enamel cannot be replaced once damaged

Term
hypsodont
Definition

rodent: continually produce enamel and must wear teeth down by chewing. root and crown grow simultaneously and constantly throughout life

horse: enamel and dentin layers are combined, increasing strength and decreasing wear rate

 

Term
importance of saliva in ruminants
Definition
buffer pH because forestomachs are non secretory
Term
nervous control of salica release
Definition
autonomic nervous system (parasympathetic)
Term
major salivary glands
Definition

further from the buccal cavity, have long ducts

 

Term
minor salivary glands
Definition
more proximal, have shorter ducts
Term
major salivary glands list
Definition

parotid

mandibular

sublingual

zygomatic (carnivore)

molar (carnivore)

Term
minor salivary glands list
Definition

labial

lingual

buccal

palatine

 

Term
adenomere or acinus
Definition

compund tubuloalveolar cells

can be mucous, serous or mixed

Term
serous demilunes
Definition
may cap any mucous end pieces
Term
myoepithelial cells
Definition
help expel saliva gland secretions
Term
intercalated ducts
Definition
small tubules lined by low cuboidal epithelium - non secretory
Term
striated intralobular ducts
Definition
lined with columnar epithelium
Term
lobular ducts
Definition
columnar lined
Term
intralobar ducts
Definition
pseudostratified lined
Term
lobar duct
Definition
pseudostratified lined
Term
excretory duct
Definition
squamous lined
Term
tunica mucosa 
Definition

innermost layer (toward lumen)

Mucosal epithelium
Lamina propria

-Muscularis mucosa

Term
lamina propria contents
Definition

Loose CT

Blood vessels

Lymphatics

Lymphocytes

Plasma cells

  

Term
tunica submucosa
Definition

meissner's plexus

fibrous connective tissue

adipose tissue (or not)

glands (or not)

GALT

vessels

Term
tunica muscularis
Definition

2 layers of smooth muscle, inner circular and outer longitudinal

(esophagus can be smooth, skeletal or mixed muscle)

vessels and myenteric plexus

 

Term
tunica serosa
Definition

-Single layer of mesothelium

-Scant fibrous CT

-Blood & lymphatic vessels

Term
tunica adventitia
Definition
Similar to T. Serosa- BUT NO mesothelial layer
Esophagus

Distal colon & Rectum

Term
t mucosa: esophagus
Definition

stratified squamous epithelium

can be keratinized or not

muscularis mucosa is discontinous and can be absent cranially (dog and pig)

Term
t submucosa: esophagus
Definition

contains glands

Most domestic animals:
Glands in the cranial third (cervical)
Dog:
Mucous glands, entire length
Pigs:
more abundant in the cranial half

do not extend into caudal half

Term
t muscularis: esophagus
Definition
Dog- mostly skeletal muscle, changes next to stomach to mixed (caudal to diaphragm)
Cat & Horse- Switches from skeletal to smooth in caudal 1/2 - 1/3 of esophagus
Ruminants- muscle layer of esophagus is entirely skeletal mm.
Inner circular muscle layers of esophagus become thick near the cardia
especially prominent in horse
 
Term
t adventitia: esophagus
Definition
Cervical and anterior mediastinum: contains vessels and connective tissue that blends with the surrounding CT
Term
t serosa: esophagus
Definition
covered by mesothelium
Term
t mucosa ruminant forestomach
Definition

keratinized

absorption

no glands

Mucosal papillae and folds
Increased surface area

Some contain smooth muscle

Term
reticulum
Definition

T. Mucosa:

vHoneycomb-

  Intersecting folds (laminae)

 

vMuscularis mucosa-

    within upper segment of

    1 fold(aka. long fold)

 

v2 papilla(aka. Conical papilla)
Term
rumen
Definition

T. mucosa:

vRuminal papillae
vKeratinized stratified squamous epithelium
vNO muscularis mucosa
vCombined lamina propria-submucosa
vNo glands
Term
omasum
Definition

T. mucosa

Keratinized stratified squamous epithelium
Lamina propria
Muscularis mucosa

 

Leaves:

Primary laminae
Secondary papilla
Term
abomasum
Definition
secretory stomach of ruminants
Term
t mucosa: glandular stomach
Definition
Columnar epithelium- mucous cells
Lamina propria

Glands: cardiac, fundic, pyloric

Gastric pits- (“foveolae”)

  tubular structures that connect to invaginations of epithelium from surface

Term
t muscularis glandular stomach
Definition
Smooth muscle:
Circular
Longitudinal
Oblique layer 
Term
gastric glands
Definition

in cardia and pylorus

Branched tubular mucous glands
Function: protect the lining of the stomach
Gastric pits of cardia- more shallow than pyloric glands
Term
gastric glands fundus and body
Definition
1.Surface mucous cells
2.Mucous neck cells
3.Parietal cells

Chief cells

Term
surface mucous cells
Definition

-  Cover the surface and line the gastric pits

-

  -  Columnar cells with basally located oval nuclei and abundant apical cytoplasm containing tiny mucous droplets. 

Term
mucous neck cells
Definition

Mucous neck cells:

  -Found at the neck of the gland

 

  - Smaller than surface mucous cells & contain less amount of mucin in the cytoplasm and round nucleus

Term
parietal cells
Definition

- Found between the mucous neck cells and chief cells

 

  - Large, polygonal cells with eosinophilic cytoplasm and central round nuclei

 

  - SECRETE:  HCl, gastric intrinsic factor 

Term
cheif cells
Definition

- Located deeper in the fundic glands

 

  - Eosinophilic apical cytoplasm (zymogen granules) and basophilic basal cytoplasm (rER

 

  - SECRETE:  pepsinogen, trypsinogen, renin (ruminant), gastric intrinsic factor (some species)

Term
t mucosa: sm intestine
Definition
Enterocytes: Simple columnar epithelium + microvilli
Goblet cells: secrete mucus (lubrication/protection)
Increase in number as move aborad
Villi: surface mucosal projections lined by epithelium
Crypts of Lieberkuhn: space between villi
rapidly proliferating cells
Lymph lacteals
Immune cells (lymphocytes, plasma cells, globular leukocytes)
Endocrine cells
Term
villi
Definition

only present in sm intestine

lionger and slender in carnivores

shorter and thicker in ruminants

microvilli increase surface area

Term
paneth cells
Definition
Clusters at base of crypts
Cells= pyramid shaped with intensely eosinophilic cytoplasmic granules & basilar nuclei

 

Secrete protein- includes lysozyme (bactericidal)
Prominent in horse, also seen in ruminants
Term
enteroendocrine cells
Definition
Triangular, argentaffin cells
Secrete:
Serotonin
Motilin
Vasoactive intestinal polypeptide (VIP)
Somatostatin
Gastrin
Term
duodenum
Definition
Brunner’s glands
Shortest villi
Lowest # goblet cells
Paneth cells
Term
ileum
Definition
Longest villi
Most goblet cells
(but less than LI)
Increased lymphoid tissue

Peyer’s patches”

Term
M cells
Definition
Epithelial cells (lack microvilli)
Found in epithelium over mucosal lymphoid tissue (Peyer’s patches)
Function= Mucosal immunity- take up antigen/organisms for transepithelial delivery to antigen presenting cells
Term
t mucosa: large intestine
Definition
NO villi, only crypts
Many goblet cells
No Paneth cells
Term
rectum
Definition
Last part of colon
Enlarged T. muscularis forms the anal sphincter
Derived from= hindgut
Term
anus
Definition
Derived from= surface ectoderm
Abrupt transition:
simple columnar with goblet cells à stratified squamous epithelium
Term
proventriculus
Definition
avian glandular stomach
Term
ventriculus
Definition

"gizzard"

avian muscular stomach

contains stones

Term
avian large intestine
Definition
short colon (Short villi extend into the lumen of the colon, unlike mammals.)
paired ceca (important sites for fermentation)
Term
cloaca
Definition
common opening of the digestive, reproductive and urinary systems
Term
crop
Definition

diverticulum of esophagus

T. Mucosa
Non-keratinized stratified squamous to columnar
Mucous glands (lacking in crop)
T. Submucosa
T. Muscularis
Entirely smooth muscle
T. Adventitia
Term
proventriculus
Definition
T. Mucosa
Folds surrounding opening of glands
Simple columnar epithelium
Lamina propria
Muscularis mucosa
T. Submucosa
Glands
T. Muscularis= thin
T. Serosa= typical
Term
ventriculus
Definition
T. Mucosa
Cuboidal to columnar epithelium
Glands
Koilin” over surface

(a.k.a. pellicle)

 

T. Submucosa
T. Muscularis
T. Serosa
Term
largest organ in the body
Definition

liver

2-5% of body weight

Term
liver cell regrowth
Definition
hepatocytes are mitotically active, but can regrow in non functional structure
Term
kuppfer cells
Definition
phagocytic cells in liver
Term
liver blood supply
Definition
Functional supply:  hepatic portal vein – originates form small intestine and spleen and supplies 4/5 of the vascular supply to the liver
Route of entry for intestinal pathogens
Nutritional supply:  hepatic artery – systemic oxygenated blood

Route of entry for blood borne organisms

Term
blood flow in liver
Definition
progresses from lobular periphery (portal triad) through sinusoids to central vein
Term
bile system
Definition

     Intrahepatic components

Bile canaliculi, interlobular bile ducts (portal triad), intrahepatic ducts

Extrahepatic components

extrahepatic ducts, hepatic ducts, cystic duct, and common bile duct.  
Term
portal triad
Definition
interlobular bile duct, artery, portal vein
Term
portal area
Definition
portal triad plus nerves, lymph, connective tissue
Term
liver units
Definition
Hepatic lobules  = morphology
Portal lobules = exocrine function
Hepatic acinus = vascular unit
Term
hepatic lobules
Definition
central vein in center
Term
portal lobule
Definition
interlobular bile duct (and triad) in center
Term
hepatic acinus
Definition
parenchyma and sinusoids of 2 adjacent hepatic lobules supplied by same interlobular vessels
Term
melanomacrophage centers
Definition

reptile liver

immune surveillance

Term
gall bladder functions
Definition

store bile

concentrate it 

epithelium produces mucus

 

Term
gall bladder structre
Definition
Innermost folds of simple columnar epithelium, connective tissue wall, smooth muscle not oriented in muscular tunics, outer tunica serosa
circular and longitudinal muscle layers in common bile duct
Term
pancreas
Definition
Compound tubuloalveolar gland
Diverticulum of the gut
Specialized glandular epithelium
Absence of striated ducts
Arranged in non-rounded lobules separated by interstitium

Also islets of endocrine tissue

Term
pancreatic acinar cells
Definition
Conical or pyramidal
Para-basal nucleus
Zymogen granules in superficial region
Intercalated ducts lined by squamous or cuboidal epithelium 
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