Term
Produces maintains and transports sperm cells |
|
Definition
|
|
Term
Defense of male reproductive system |
|
Definition
|
|
Term
Produces eggs in a 28 day cycle |
|
Definition
Female reproductive system |
|
|
Term
|
Definition
Defense of female reproductive system |
|
|
Term
|
Definition
Defense of female reproductive system |
|
|
Term
|
Definition
Defense of female reproductive system |
|
|
Term
|
Definition
|
|
Term
Shedding of epithelial cells lining the urinary tract |
|
Definition
|
|
Term
|
Definition
|
|
Term
Lysozyme and lactoferrin in urine |
|
Definition
|
|
Term
|
Definition
|
|
Term
Normal biota of the male urethra and genital tract |
|
Definition
Nonhemolytic Streptococci |
|
|
Term
Normal biota of the male urethra and genital tract |
|
Definition
|
|
Term
Normal biota of the male urethra and genital tract |
|
Definition
|
|
Term
Normal biota of the male urethra and genital tract |
|
Definition
|
|
Term
Only anatomic areas of normal flora of the female genital tract |
|
Definition
Anterior urethra and vagina |
|
|
Term
Flora of the vagina depends on these factors |
|
Definition
|
|
Term
Greatly influences normal flora of the vagina |
|
Definition
|
|
Term
In utero, the fetal vagina contains these bacteria |
|
Definition
|
|
Term
How does a new born vagina acquire normal flora |
|
Definition
Hands of caregivers, infants feces |
|
|
Term
In the first six weeks of life estrogens are present in the infant vagina, what normal flora predominates |
|
Definition
|
|
Term
In the absence of estrogen (pre puberty years) this bacteria is present as normal flora of the vagina |
|
Definition
|
|
Term
In the absence of estrogen (pre puberty years) this bacteria is present as normal flora of the vagina |
|
Definition
|
|
Term
In the absence of estrogen (pre puberty years) this bacteria is present as normal flora of the vagina |
|
Definition
|
|
Term
After menarche (in the presence of estrogen) the vagina is dominated by this normal flora |
|
Definition
|
|
Term
After menarche (in the presence of estrogen) the vagina is dominated by this normal flora |
|
Definition
Gram (+) and gram (-) anaerobes and facultative anaerobes |
|
|
Term
After menopause (absence of estrogen) this bacteria decreases in numbers |
|
Definition
|
|
Term
May lead to UTI's in the anterior urethra of a female |
|
Definition
|
|
Term
May lead to UTI's in the anterior urethra of a female |
|
Definition
|
|
Term
May lead to UTI's in the anterior urethra of a female |
|
Definition
|
|
Term
May lead to UTI's in the anterior urethra of a female due to fecal spread |
|
Definition
|
|
Term
May lead to UTI's in the anterior urethra of a female due to fecal spread |
|
Definition
|
|
Term
UTI infecting the bladder |
|
Definition
|
|
Term
|
Definition
|
|
Term
UTI infecting the urethra |
|
Definition
|
|
Term
UTI leading to a burning pain with urination |
|
Definition
|
|
Term
Cloudy urine is consistent with presence of |
|
Definition
|
|
Term
Orange urine is consistent with presence of |
|
Definition
|
|
Term
Back pain is consistent with a UTI infecting this organ |
|
Definition
|
|
Term
If pyelonephritis is inadequately treated it can lead to |
|
Definition
|
|
Term
Most common causative agent of UTI |
|
Definition
|
|
Term
Catalase (+) causative agent of UTI |
|
Definition
Staphylococcus saprophyticus |
|
|
Term
Urease (+) causative agent of UTI, member of Enterobacteriaceae |
|
Definition
|
|
Term
Community acquired UTIs are usually a result of this form of transmission |
|
Definition
|
|
Term
UTIs are more common in women than men do to this anatomical feature of the urethra |
|
Definition
Shorter length of female urethra |
|
|
Term
UTIs are more common in women than men do to the location of these anatomical structures |
|
Definition
Close proximity of anus and urethral opening |
|
|
Term
Recurrent UTIs in some women are do to E coli invading deeper tissues of the urinary tract allowing for this |
|
Definition
|
|
Term
Most common nosocomial infection |
|
Definition
|
|
Term
Treatment for UTI includes antibiotics plus ____ to control burning and urgency |
|
Definition
|
|
Term
Bacteria causing Weils disease |
|
Definition
|
|
Term
Long Gram -, spirochetes with hooked ends |
|
Definition
|
|
Term
Invasion is via mucosa or broken skin, there is no lesion at site of entry, may lead to severe systemic disease |
|
Definition
|
|
Term
Generalized infection may lead to systemic infection including: renal and hepatic failure, extensive vasculitis, myocarditis, and death. Invasion of CNS leads to meningitis |
|
Definition
|
|
Term
Symptoms including fever with relapses, Jaundice may occur in severe cases with renal failure being the most common cause of death |
|
Definition
|
|
Term
Worldwide zoonotic disease with a variety of hosts. Rodents (mainly rats) can shed the bacteria their entire lives through urine |
|
Definition
|
|
Term
In the US rats, dogs, farm animals are the major source of human infection. Bacteria are discharged through urine and transmitted to humans via infected soil, water, and food |
|
Definition
|
|
Term
Organisms can survive for months in water or wet soils, no person to person transmission has been documented |
|
Definition
|
|
Term
Culture and microscopy are insensitive, main form of diagnosis is through microscopic agglutination using the patients serum and live bacteria |
|
Definition
|
|
Term
Treatment includes antibiotics, there is a vaccine available but only targets specific strains used primarily for the military |
|
Definition
|
|
Term
Vaginal itching, burning, inflammation |
|
Definition
|
|
Term
Vaginal itching, burning, discharge |
|
Definition
|
|
Term
Most common cause of vaginosis |
|
Definition
|
|
Term
Gram +, but appears gram - |
|
Definition
|
|
Term
Increased prevalence indicates a role in BV but not a sole etiologic agent |
|
Definition
|
|
Term
Gram +, thought to maintain acidic pH by metabolism of glucose |
|
Definition
Lactobacillus crispatus, Lactobacillus jensenii |
|
|
Term
In females with BV these bacteria are replaced by Gardnerella vaginalis and other anaerobic flora |
|
Definition
Lactobacillus crispatus, Lactobacillus jensenii |
|
|
Term
No gram reaction, higher incidence in women with BV |
|
Definition
|
|
Term
Gram +, obligate anaerobe, very high incidence in women with BV |
|
Definition
|
|
Term
Gram -, obligate anaerobe, higher incidence in women with BV |
|
Definition
|
|
Term
This bacteria uses lactic acid production (low pH) and production of H2O2 (high oxidation-reduction) to inhibit overgrowth of less desirable anaerobic vaginal flora from causing vaginosis |
|
Definition
|
|
Term
Product of Mobiluncas causing irritation of the mucus membranes |
|
Definition
|
|
Term
Amines, malic acid, endotoxin, collagenases, proteases play a role in causing |
|
Definition
|
|
Term
This virulence factor of Mobiluncus and Gardnerella vaginalis increases with increasing pH |
|
Definition
|
|
Term
Not considered a sexually transmitted disease but is more common in women that are sexually active |
|
Definition
|
|
Term
Clinical diagnosis includes Vaginal fluid with pH>4.5, homogenous adherent discharge, fishy odor on 10% K (due to metabolic products), clue cells (obscure borders) |
|
Definition
|
|
Term
Gram stain diagnosis based on quantization of large gram + bacilli |
|
Definition
|
|
Term
Gram stain diagnosis based on quantization of smaller gram - |
|
Definition
|
|
Term
Complications include pelvic inflammatory disease, adverse outcome of pregnancy (preterm birth, premature rupture of membranes, postpartum endometritis, cellulitis |
|
Definition
|
|
Term
Treatment includes metronidazole (PO, cream, lactate gel), clindamycin (cream), |
|
Definition
|
|
Term
Bacterial infection usually from intestinal tract, may be a consequence of a UTI |
|
Definition
|
|
Term
Often bacterial infection, sometimes not, cases do not respond to antibiotics and are thought to be of mixed populations of bacteria in biofilms |
|
Definition
|
|
Term
Symptoms include pain: pelvic, back, genital, ejaculation. Frequent urge to urinate, blood in urine, |
|
Definition
|
|
Term
Gram -, cocci poses fimbriae and capsules |
|
Definition
|
|
Term
Diplococci within PMNs, adjacent flattened ends |
|
Definition
|
|
Term
Facultative anaerobe susceptible to environmental conditions. Fastidious, enhanced growth at high CO2, thayer martin medium |
|
Definition
|
|
Term
Fimbriae for adherence, antigenic variation, and promotion of endocytosis |
|
Definition
|
|
Term
Contain IgA protease that cleaves IgA on mucosal surfaces |
|
Definition
|
|
Term
Outer membrane contains Lipooligosaccharide (LOS) |
|
Definition
|
|
Term
This virulence factor of Neisseria gonorrhea elicits an inflammatory response causing purulent discharge |
|
Definition
|
|
Term
Lack of immunity leads to repeat infections due to phase variation |
|
Definition
|
|
Term
Primary sites of infection include: urethra in ment, urethra and cervix in women. Men are more symptomatic than women |
|
Definition
|
|
Term
In males clinical symptoms include burning on urination and yellow purulent discharge. Complications may occur but are uncommon |
|
Definition
|
|
Term
In females clinical symptoms include burning or frequent urination, vaginal discharge, abdominal pain. Infection can spread externally to the rectum in about 1/2 the cases. Major complication is PID leading |
|
Definition
|
|
Term
Opthalmia neonatorumthis occuring through passage of infected birth canal, rationale for mixed antibiotic prophalxis for newborns |
|
Definition
|
|
Term
One of the most frequently reported diseases in the US and 2nd most common cause of venereal disease |
|
Definition
|
|
Term
Almost always sexually transmitted with humans being the only reservoir |
|
Definition
|
|
Term
One of the more common cause of purulent arthritis in adults (mainly women) |
|
Definition
|
|
Term
Very low percentage of cases (mainly women) develop arthritis dermatitis syndrome which includes arthritis and dermatitis of the wrists, elbows and ankles |
|
Definition
|
|
Term
Gram stain conclusive for male purulent material. In females cervical secretions not conclusive, need to do either ELISA or PCR for confirmation |
|
Definition
|
|
Term
Used for testing antibiotic sensitivity of Neisseria gonorrhea |
|
Definition
|
|
Term
Disadvantage of using this type up test is no antibiogram |
|
Definition
|
|
Term
May be resistant to penicillin or tetracycline |
|
Definition
|
|
Term
Very small gram -, contains LPS but little peptidoglycan |
|
Definition
|
|
Term
Obligate intracellular parasite, development occurs in 3 phases |
|
Definition
|
|
Term
Infection of mucosa membranes through small abrasions, may lead to granuloma formation |
|
Definition
|
|
Term
Most females are asymptomatic, however, manifestation includes mucopurulent cervicitis and PID |
|
Definition
|
|
Term
PID more severe than N gonorrhoeae |
|
Definition
|
|
Term
In males most genital infections are symptomatic, manifestation includes mucopurulent urethritis |
|
Definition
|
|
Term
Manifestation leads to proctitis |
|
Definition
|
|
Term
Bacteria causing lymphogranuloma venereum |
|
Definition
|
|
Term
Primary lesion at site of infection is usually overlooked by it is small, and heals rapidly. Later manifestation includes painful enlargement of lymph nodes draining site of infection (usually inguinal) |
|
Definition
|
|
Term
Neonatal conjunctivitis from exposure at birth as well as infant pneumonia |
|
Definition
|
|
Term
Most common bacterial disease |
|
Definition
|
|
Term
Most common sexually transmitted disease |
|
Definition
|
|
Term
Most common cause of epididymitis in sexually active men |
|
Definition
Chlamydia trachomatis, Neisseria gonorrhoeae |
|
|
Term
Chlamydia trachomatis disease epidemic to Africa, asia, and S america. |
|
Definition
|
|
Term
Most common form of neonatal conjunctivitis in the US |
|
Definition
|
|
Term
Gold standard for diagnosis of Chlamydia trachomatis, however, is starting to be replaced by molecular diagnosis |
|
Definition
|
|
Term
Urine samples of Chlamydia trachomatis can be used for this test if purulent discharge is not available |
|
Definition
|
|
Term
Treatment includes agents that are taken up by host cells effectively |
|
Definition
|
|
Term
Gram -, but lacks a true cell wall |
|
Definition
Ureaplasma urealyticum, Mycoplasma genitalium |
|
|
Term
Cause GI infections (urethritis in men) that are nongonnoccocal and nonchlamydial |
|
Definition
Ureaplasma urealyticum, Mycoplasma genitalium |
|
|
Term
In women, known to cause chorioamnionitis and postpartum fever |
|
Definition
Ureaplasma urealyticum, Mycoplasma genitalium |
|
|
Term
Diagnosis is usually not done |
|
Definition
Ureaplasma urealyticum, Mycoplasma genitalium |
|
|
Term
If urethritis persists after doxycycline treatment, treat with azithromycin |
|
Definition
Ureaplasma urealyticum, Mycoplasma genitalium |
|
|
Term
Gram -, spirochete, helically coiled, long corkscrew-shaped |
|
Definition
|
|
Term
Too thin too observe with light microscope |
|
Definition
|
|
Term
Periplasmic flagella allow corkscrew movement |
|
Definition
|
|
Term
Microaerophile, long generation time contributing to long incubation |
|
Definition
|
|
Term
Can infect almost every tissue in the body making it a great imitator |
|
Definition
|
|
Term
Painless slow evolving chronic granulomas disease |
|
Definition
|
|
Term
Causative agent of syphilis |
|
Definition
|
|
Term
Fluctuates between short symptomatic and long asymptomatic stages |
|
Definition
|
|
Term
Impedes access to bacterial antigens when coated with fibronectin which protects against phagocytosis |
|
Definition
|
|
Term
Long incubation, invasion through mucus membrane or abrasion in skin, dissemination via lymphatics or blood |
|
Definition
|
|
Term
This bacteria causes progression of disease that manifests in 3 clinical stages: primary, secondary, tertiary. The disease can go into a latent stage |
|
Definition
|
|
Term
This stage of syphilis is characterized by a hard chancre with painless regional lymph node enlargement. There are no other systemic signs and the majority of patients may not know they have the disease |
|
Definition
|
|
Term
This stage of syphilis is characterized by several alternating relapses. Hallmark is a rash commonly on the palms and soles. Condylomata may occur on the mucous membranes |
|
Definition
|
|
Term
Stage of syphilis classified as the first 4 years between secondary and tertiary stages |
|
Definition
|
|
Term
Stage of syphilis classified as 4-40 year period between secondary and tertiary stages |
|
Definition
|
|
Term
Stage of syphilis that progresses slowly painless granulomas of the skin and bones develop known as gummas |
|
Definition
|
|
Term
Congenital disease via transplacental infection. Manifestations include: interstitial keratitis, notched incisors, CN 8 deafness |
|
Definition
|
|
Term
Primary stage is a risk factor for HIV |
|
Definition
|
|
Term
Cannot be cultured in vitro, can be grown on tissue culture at reduced O2 |
|
Definition
|
|
Term
Bacteria can be observed in lesion material using dark field microscopy for those patients with primary chancre, secondary lesions, and congenital infections |
|
Definition
|
|
Term
Wasserman Ab are specific for |
|
Definition
|
|
Term
If positive wasserman Ab suspect this bacteria |
|
Definition
|
|
Term
|
Definition
|
|
Term
This test is used to confrim nontreponemal tests |
|
Definition
|
|
Term
Treatment for early stages of syphilis |
|
Definition
|
|
Term
Used to treat late and congenital stages of sypihlis |
|
Definition
|
|
Term
Due to the slow growth of this bacteria, treatment needs to be prolonged for it to be effective |
|
Definition
|
|
Term
Sexually transmitted infection characterized by painful sores in the genital area |
|
Definition
|
|
Term
Similar to primary syphilis however a painful ulcer develops known as chancroid |
|
Definition
|
|
Term
|
Definition
|
|
Term
Genome and structure of HSV1 and HSV2 |
|
Definition
|
|
Term
Viral infection can be lytic or latent usually a result of direct inoculation of the: eyes, respiratory, mouth, genitals, and anus |
|
Definition
|
|
Term
For fast results do PCR of DNA, virus can be obtained from vesicles but not crusted lesions. Tzanck smear shows epidermal multi-nucleated cells and eosinophilic intranuclear inclusions |
|
Definition
|
|
Term
Active lesions of this virus should be cared for away from high risk group including: burn patients, eczema, neonates, immunocomprimised |
|
Definition
|
|
Term
Treatment for HSV1 or HSV2 in immunocomprimised |
|
Definition
|
|
Term
What is used to treat herpes keratitis |
|
Definition
|
|
Term
|
Definition
|
|
Term
Genome and structure of HPV |
|
Definition
|
|
Term
Virus causing warts know as papillomas |
|
Definition
|
|
Term
Genital warts from this virus rarely cause discomfort or pain but may lead to cancer of the genitals, anus, mouth, and URT |
|
Definition
|
|
Term
These serotypes are in the vaccine for HPV |
|
Definition
|
|
Term
HPV squamous cell with a larger irregular nucleus appear rounded and in clumps |
|
Definition
|
|
Term
Visible warts typically do not cause cancer from this virus. hard to detect warts may be made more visible by using vinegar |
|
Definition
|
|
Term
If pap smear is inconclusive, follow up test is a ___ DNA test for this virus |
|
Definition
|
|
Term
|
Definition
|
|
Term
Asymptomatic shedding promotes transmission usually through direct contact, warts may spread through auto inoculation and fomties |
|
Definition
|
|
Term
HPV treatment for immunocompromised |
|
Definition
|
|