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Heat; Kinetic energy associated with the random movement of atoms |
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Movement; the relative motion of objects |
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Energy that matter possesses based on location and structure |
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Potential energy available for release in a chemical reaction |
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First law of Thermodynamics |
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Energy cannot be created or destroyed, just transferred or transformed |
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2nd law of Thermodynamics |
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Definition
During every transfer or transformation, some energy is lost as heat which contributes to the increase of entropy in the universe |
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Can do work when temperature and pressure are uniform (potential energy, known as G) |
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Measure of disorder, randomness or chaos |
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Endergonic: energy released, spontaneous, decrease in G Exergonic: requires energy, non-spontaneous, increase in G |
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Energy Coupling (within a metabolic pathway) |
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Definition
The use of an exergonic process to drive an endergonic one. |
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How is ATP useful in energetic coupling? |
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Definition
Responsible for mediating most energy coupling in cells. Hydrolysis of ATP can be used to drive an endergonic reaction |
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Initial energy needed to start a chemical reaction (EA) |
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Definition
Macromolecule that acts as a catalyst (lowers E subA). |
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The reactant and enzyme acts on. |
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Specific region of the enzyme which binds to a substrate (or substrates). |
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Adjunct that is bound to an enzyme either permanently or loosely along with the substrate - performs a crucial chemical function in catalysis. |
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Inhibitor (competitive and non-competitive) |
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Definition
Competitive: resemble a normal substrate molecule and compete for admission to the active site Non-competitive (or allosteric): Impede enzymatic reactions by binding to another part and changing the enzyme shape |
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Definition
A kind of allosteric activation in which a substrate molecule binds to one active site in a multisubunit enzyme triggers a shape change in all subunits thereby increasing catalytic activity at other active sites. |
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Definition
A metabolic pathway is switched off by using it's end product as an allosteric inhibitor on an enzyme that acts early in the pathway |
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Definition
Exergonic processes in the cell are couple to regeneration of ATP (phosphorylation of ADP). |
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