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Metabolism - hard
Microbiology final, Mission College, Biosc 4
12
Biology
Undergraduate 2
05/18/2008

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Cards

Term
Second law of thermodynamics
Definition
  • total amount of energy is flowing from high- to lower- energy forms
  • In any energy conversion, the amount of usable energy for work decreases
Term
Metabolic pathway
Definition
organized series of chemical reactions catalyzed by enzymes in a living system; often regulated as a unit
Term
Cofactors and coenzymes
Definition
non-protein substances that are necessary for the activity of an enzyme
Term
Enzyme specificity
Definition

only a single type of substrate can bind to the active site (substrate-specific)

 

Term
Enzyme activity: 4 steps
Definition
  1. enzyme associates with a specific substrate molecule
  2. enzyme forms an enzyme-substrate complex (temporary compound)
  3. bonds within the substrate are broken and form products that are released
  4. enzyme dissasociates from the newly formed molecule and returns to its original configuration
Term
What is the effect of low substrate concentrations on an enzyme?
Definition
enzyme makes product slowly because it rarely contacts the substrate molecule
Term
What is the effect of having more substrate molecules present?
Definition
Enzyme binds substrate more often and the reaction velocity (rate of product formation) increases
Term
What is the relationship between an enzyme-catalyzed reaction and substrate concentration?
Definition

The rate of an enzyme-catalyzed reaction increases with substrate concentration

 

this continues until the enzyme becomes saturated with the substrate and operates at maximum velocity

Term
Competetive inhibitors
Definition

bind directly to the active site of the enzyme to prevent the substrate from binding

 

(do not undergo chemical reactions to form products)

Term
What is the effect of a noncompetetetive inhibitor that binds to an allosteric site?
Definition
alters the shape of the active site so that the substrate cannot be bound
Term
Entropy
Definition

Measure of disorder in a system

 

 

Term
Catalyst
Definition
  • chemical involved in a chemical reaction
  • not consumed or changed in the reaction 
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