Shared Flashcard Set

Details

Metabolic Overview
NA
17
Medical
Professional
08/08/2011

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Cards

Term
T/F. The liver can store triglycerides.
Definition
False. THe liver stores glycogen and converts glucose to triglycerides which get packaged and transported to adipose tissue.
Term
Why are red blood cells unable to use fuel sources other than glucose?
Definition
They lack mitochondria.
Term
Where in the cell does glycolysis, gluconeogenesis and FA synthesis occur?
Definition
In the cytosol.
Term
What metabolic processes occur in mitochondria?
Definition
Beta oxidation, the TCA cycle, and ETC.
Term
T/F. NAD+, NADH, and CoA act as electron carriers passing back and forth across the mitochondrial membrane.
Definition
False. Separate pools exist on both sides of the membrane.
Term
Where are glycogen stores available for export for other cells of the body?
Definition
The liver.
Term
T/F. Fatty acids or ketones can never be converted to glucose.
Definition
True
Term
What three carbon sources  can be used in gluconeogenesis?
Definition
Lactate, gluconeogenic amino acids, glycerol.
Term
T/F. Insulin levels rise during the fed state and glucagon levels fall.
Definition
False. Insulin levels increase, however glucagon levels remain relatively constant.
Term
How are enzymes needed during a fast regulated?
Definition
Glucagon signals for phosphorylation of these enzymes. Oppositely enzymes not used during the fasting state are unphosphorylated during a fast.
Term
Amino acids that are not gluconeogenic are considered what? What can they be used for?
Definition
Ketogenic. Can be catabolized in the liver for energy. Ketogenic amino acids do not necessarily have to form ketones.
Term
What happens to the nitrogen of amino acids that are catabolized?
Definition
The nitrogen is not ketabolized, instead it is converted to urea via the urea cycle.
Term
How is NADP+ reduced?
Definition
The pentose/phosphate pathway reduces the oxidized NADP+
Term
Is anabolism a reductive or oxidative process?
Definition
Reductive process--add electrons so you can later cleave those bonds for energy.
Term
Is catabolism a oxidative or reductive pathway?
Definition
Oxidative.
Term
What are the various catabolic processes? What molecules are they oxidizing?
Definition
-Glycolysis--oxidizing glucose
-Beta oxid--oxidizing fatty acids
-Krebs cycle--oxidizes metabolites from glycolysis (pyruvate), B oxid ( ), alcohol, amino acids
Term
What metabolites can be converted to acetyl coA to enter the TCA cycle?
Definition
-Alcohol
-fatty acids
-Pyruvate
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