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Mesodermal Centric Perspective
8/30/11 First Lecture
20
Medical
Graduate
08/30/2011

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Cards

Term
Define Coelom
Definition
The usually epithelium lined space between the body wall and the digestive tract
Term
Define Splanchnic
Definition
Of or relating to the viscera
Term
Define Viscus
Definition
An internal organ of the body located in the trunk proper
Term
Define Somatic
Definition
Of or relating to the wall of the body
Term
Define Parietal
Definition
Of or relating tot he wall of a part or cavity
Term
Define Axial
Definition
Relating to or situated in the central part of the body. In the head or trunk, not the limbs.
Term
Define Somite
Definition
One of the longitudinal series of segments into which the body of many animals is divided
Term
What are the 3 paired veins that drain into the heart of the 4 week embryo
Definition
Vitelline
Cardinal
Umbilical
Term
What is the origin of the mesoderm?
Definition
The mesoderm is derived from cells in the epiblast that migrate down the primitive streak in the later stages of gastrulation and as such sit between the endo and ecto derm
Term
What are the 3 subsets of the mesoderm that it gets split into?
Definition
Intermediate, lateral, and paraxial
Term
What 2 subsets does the lateral mesoderm split into?
Definition
Splanchnic and Somatic
Term
What body structures does the Paraxial mesoderm give rise to?
Definition
After organizing into somites, the paraxial mesoderm differentiates into the axial skeleton, muscles, limb muscles, and the dermis
Term
What body structures does the intermediate mesoderm give rise to?
Definition
The urogenital system
Term
What body structures does the splanchnic mesoderm give rise to?
Definition
Visceral pleura, mesenteries, epicardium, blood cells, blood vessels, endocardium (organs mostly)
Term
What body structures does thee somatic mesoderm give rise to?
Definition
Skeletal limbs and parietal pleura, pericardium, and peritoneum (body wall lining mostly)
Term
Describe the process of lineage tracing
Definition
1. Remove part of the somites from a sample
2. Replace with "tagged" somites
3. See where the "tagged" somites end up
Term
What is the process by which muscle cells are formed from myoblasts?
Definition
1. Myoblasts leave the cell cycle
2. Myoblasts fuse to form a myotube (multiple mononucleate myoblasts fuse to form a syncytium)
3. Units assemble into sarcomeres
4. Fusion with satellite cells for growth
Term
What are the two major types of bone formation?
Definition
Endochondral ossification

Intramembranous bone formation
Term
How does endochondral ossification work?
Definition
1. Cartilage model of bone forms in mesenchymes
2. Throughout embryogenesis, true bone replaces this cartilage

Note: Most bones are formed this way
Term
How does Intramembranous bone formation work?
Definition
Direct ossification of mesenchymal cells (no cartilaginous intermediate)

Superfical face and skull bones form this way
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