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Men's and Women's Health EXAM 2
Men's and Women's Health EXAM 2 - Butler
70
Pharmacology
Graduate
11/03/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
the menstrual cycle
Definition
DAY 1
the day menses first appears

DAY 1-4 (length varies per person)
menstruation

"FERTILE WINDOW"
days 10-17 (unpredictable)
in the middle of the menstrual cycle

[image]

during the menstrual cycle (0-5) there is a low level of estrogen and progesterone and FSH and LH are low

the endometrium thickens and becomes a favorable environment for implantation

ovulation occurs; LH and FSH surge occurs at ovulation

after fertilization, the ovum is ready to implant on the endometrium

for the endometrium to be favorable it has to be thick

at the end of the cycle, when the hormones decrease then the endometrium is sloughed

to suppress the LH and FSH surge, it would prevent ovulation from occurring
Term
methods of contraception
Definition
contraception: prevention of pregnancy following sexual intercourse by
1) inhibiting viable sperm from coming into contact with a mature ovum (barriers or prevent ovulation)
2) preventing a fertilized ovum from implanting successfully in the endometrium (create an unfavorable uterine environment)

goal: planned and desired pregnancies
Term
benefits of contraception
Definition
control the rapid population growth that has begun to threaten human survival

essential to a woman's ability to achieve her individual goals and to contribute to her sense of well being
Term
consideration of choice
Definition
effectiveness
safety
accessibility
acceptability
complexity
spontaneity
cost
Term
natural contraception methods
Definition
lactational infertility (amenorrhea)

infant receives only breast milk and mother does not have menses

baby suckling on mother's nipples causes surge in maternal prolactin, which inhibits estrogen production and ovulation

may last up to 6 months

HIGH FAILURE RATE
Term
contraceptive failures
Definition
TYPICAL USE FAILURE = USER FAILURE
failure that occurs secondary to person using methods, following directions correctly and consistently
ex) taking the medication and vomiting; taking the medication while taking antibiotics

PERFECT USE FAILURE = METHOD/PRODUCT FAILURE
failure that subject has no control over, does not depend on the proper use of contraceptive alone
Term
mechanism of action for hormonal contraceptives
Definition
ESTROGEN

suppress FSH, preventing development of a dominant follicle
suppress LH
stabilize endometrial lining: bleeding control
potentiates progestin's action
induction of luteolysis (degradation of corpus luteum, not allowing implantation)
accelerated ovum transport

PROGESTIN

suppress FSH and LH surge, inhibiting ovulation
thickens cervical mucus
atrophies (thins) endometrium: inhibition of implantation
inability of capacitation: inhibits activation of spermatic enzymes needed for penetration into ovum
slows ovum transport

just progesterone will not give the optimal suppression of FSH and LH
Term
hormonal contraception examples
Definition
oral: combination (estrogen and progestin) - COCs; progestin only - POPs

vaginal ring

transdermal patch

injectable

intrauterine devices (IUD)
Term
most common estrogens in oral contraceptions
Definition
1980s FDA states no OCs are to have > 50 mcg of estrogen; the higher the amount of estrogen, the more at risk of complications and ADRs

mestranol (ME): present in older pills, liver biotransforms mestranol to ethinyl estradiol

ethinyl estradiol (EE): most commonly used
Term
most common progestins used in oral contraception
Definition
progestins can have progestin activity, estrogenic activity, and androgenic activity

androgenic activity may cause male-like characteristics: hair growth (hirsutism), oily skin, increased sex drive

if someone is complaining of low sex drive, consider switching to a higher androgenic activity progestin

if someone is complaining of oily skin and hair growth then want to switch them to a progestin with less androgenic activity

levonorgestrol is the most common progestin used
Term
progestins with high androgenic activity
Definition
norgestrel (levonorgestrel is the active isomer of norgestrel)
norethindrone
ethynodiol
Term
progestins with low androgenic activity
Definition
desogestrel
norgestimate
drospirenone has anti-androgenic effects
Term
combination products - 21 day regimens vs. 28 day regimens
Definition
21 day regimen:
take the pills for 21 days and on days 22-28 don't take anything or continue taking the pills

28 day regimen: active pills for 21 days and on days 22-28 they take placebo pills (to help remember to take the pills every day)
Term
monophasic vs. multiphasic
Definition
monophasic:
same amount of estrogen and progestin in all of the pills

multiphasic:
to prevent break through bleeding
OCs are supposed to mimic the menstrual cycle, normally the levels fluctuate throughout the cycle

biphasic: start at a low dose of estrogen and titrate to a higher dose of estrogen

triphasic: 3 levels of estrogen

multiphasic OCs usually contain the same level of progesterone in each tablet

less break through bleeding with muliphasic OCs; shorter menses
Term
progestin only (POP)
Definition
21 day regimen

monophasic

you can take the week off, but it is recommended to continue to take the pills (do not take a break)

less suppression of LH and FSH; only a 3 hour window to take the pill

combination products: should take around the same time each day, but doesn't matter as much as with the POPs

less effective than COCs with typical use

irregular and unpredictable menstrual bleeding

may not inhibit ovulation completely

risk of ectopic pregnancy
Term
selecting an OC for your patient: initial choice for a young, healthy female with no pre-existing conditions
Definition
low-dose combination oral contraceptive

30-35 mcg ethinyl estradiol

metabolically neutral progestin (doesn't have high androgenic activity)

multiphasic
Term
first day or Sunday start or quick start
Definition
first day:
use hormonal contraceptive during the first 24 hours of menstrual cycle

Sunday start:
1st Sunday after start of menstrual cycle
MUST USE BACK UP FOR 1ST 7 DAYS

quick start (any day):
MUST USE BACK UP FOR 1ST 7 DAYS
Term
patient instructions: combination oral contraceptive
Definition
begin on day 1 or Sunday after start of menstrual cycle

take one pill daily for 21 days; then may take placebo pills (28 day pills) or stop for 7 days

NOTE: important to take pill ~ the same time each day esp. with decreased hormone content
Term
patient instructions: progestin only
Definition
begin on day 1 of menstrual cycle
no other options with progestin only except to begin on day 1 of the menstrual cycle

take one pill every day continuously at the same time
ONLY HAVE A 3 HOUR WINDOW WITH PROGESTIN ONLY!

use another birth control method for next 48 hours if more than 27 hours between pills or miss 1 pill

NOTE: important to take pill ~ the same time each day (+/- 3 hours)
Term
side effects of COCs
Definition
nausea, vomiting
headaches
dizziness
spotting and bleeding
mood changes including depression
possible weight gain

side effects worse in the 1st 3 months:
nausea/dizziness
cyclic weight gain, edema
breast fullness, tenderness
BTB
contact lenses fail to fit: due to estrogens making the eyes swollen; fixed by decreasing estrogen component
abdominal cramping
Term
side effects of POPs
Definition
spotting
breakthrough bleeding: do not have the stabilization of the endometrium from estrogens
amenorrhea
mood changes
headaches
hot flashes
Term
COC side effects requiring an adjustment: symptoms of ESTROGEN EXCESS
Definition
nausea
bloating
hypermenorrhea
hyperpigmentation
hypertension
migraine headache
leg cramps
cervical mucorrhea
Term
COC side effects requiring an adjustment: symptoms of ESTROGEN DEFICIENCY
Definition
irritability
early and/or midcycle breakthrough bleeding
nervousness
Term
COC side effects requiring an adjustment: symptoms of PROGESTIN EXCESS
Definition
increased appetite
weight gain
hypomenorrhea
oily skin and hair
acne
hair loss or hirsutism (if androgenic)
depression
Term
COC side effects requiring an adjustment: symptoms of PROGESTIN DEFICIENCY
Definition
late breakthrough bleeding
weight loss
hypermenorrhea
amenorrhea
Term
postpartum use of birth control in non-breastfeeding women
Definition
Category 1: > 42 days

Category 2: 21-42 days without risk factors

Category 3: 21-42 days with risk factors for VTE (> 35y, previous VTE, thrombophilia, immobility, postcesarean delivery, smoking, transfusion at delivery, BMI > 30, postpartum hemorrhage)

Category 4: < 21 days

WITH RISK FACTORS: START AT 42 DAYS
WITHOUT RISK FACTORS: START AT 21 DAYS
Term
postpartum use of birth control in breastfeeding women
Definition
Category 2: > 42 days; 30-42 days without risk factors

Category 3: 30-42 days with risk factors; 21-30 days with or without risk factors

Category 4: < 21 days

COC IN BREAST FEEDING WOMEN CAN BE STARTED (WITHOUT ANY RISK FACTORS OR WITH RISK FACTORS) AT 42 DAYS
Term
postpartum, lactating: use of progestin only OC
Definition
should not be initiated < 1 month postpartum

decreased natural anticoagulants, hypercoaguable state

low dose COCs can be used: concerns of decreased milk production

pelvic rest recommened for 4 weeks (vaginal delivery) or 6 weeks (Caesarean)
Term
COC CONTRAINTICATIONS (WHO CATEGORY 4)
Definition
DVT/PE or history of

CVD, CAD

complicated DM: nephropathy, retinopathy, neuropathy, diabetes for more than 20 years

breast cancer or strong family history

pregnancy

lactation (<6 weeks postpartum)

gallbladder disease: the estrogen component can cause gallstones, can worsen gallbladder disease

hypertension: > 160/100; get blood pressure under control first

liver abnormalities: metabolized in the liver
HA or migraines with neurologic symptoms: rare cases of retino-thrombosis associated with COC; if you have migraines with neurologic symptoms you are at increased risk of retino-thrombosis; neurologic symptoms = seizures

major surgery: hypercoaguable state

>25 yo + smoker: nicotine and age and estrogen puts them at risk for clots; DO NOT USE A PRODUCT WITH ESTROGEN IN IT

undiagnosed abnormal bleeding
Term
complications associated with COC use
Definition
myocardial infarction and ischemic stroke

venous thromboembolism

hypertension - small increase

cholelithiasis/cholecystitis - gallbladder disease

visual changes

symptoms of concern:

ACHES - KNOW THESE!!

abdominal pain (possible gallbladder disease)
chest pain (possible MI)
headaches which are severe (stoke)
eye problems: blurred or loss of vision (retinal thrombosis)
severe leg pain (DVT)
Term
assessing the patient
Definition
date of last menstrual period

regularity in cycles

incidence of PMS

previous treatment

physical exam:
BP
breast examination
PAP smear
liver evaluation
family history
social history
Term
progestin only candidates
Definition
smokers > 35 years of age

history of thromboembolic events

nursing moms (low dose COC's can also be used)

history of estrogen related headaches

uncontrolled hypertension

any estrogen related side effect
Term
special populations: smokers
Definition
> 15 cigarettes per day and > 35 years old = NO ESTROGEN CONTAINING OCS
risks exceed pregnancy risk

< 15 cigarettes per day and > 35 years old = use with caution

may use low dose 20 mcg estrogen formulation

progestin only pills - recommended as best option
Term
special populations: hypertension
Definition
estrogen - small increases in blood pressure

blood pressure restoration 3-6 months after D/C

low dose estrogen OCs ok if well controlled

end organ disease (CAD, CHF, CVD) = NO!!!

K+ cautions
yaz and yasmin can increase K and cause hyperkalemia b/c it contains a different type of progesterone
Term
special populations: diabetes
Definition
no significant effects on insulin, glucose or glucagon release

women with diabetes AND vascular disease = NO
Term
special populations: dyslipidemia
Definition
progestins: decrease HDL and increase LHL

estrogens: increase removal of LHL from circulation and increase HDL

estrogens alter VLHL composition and increase triglycerides

uncontrolled (LHL > 160, HDL < 35, TGs > 250) + additional risk factors = USE ALTERNATIVE METHOD
Term
special populations: systemic lupus erythematosus
Definition
risk associated with pregnancy is high

association between VTE and OCO use in women with:
systemic lupus erythematosus
history of vascular disease
antiphospholipid antibodies

POPs should be used
Term
drug interactions
Definition
hepatic induction (enzyme inducers):
st. john's wort, RIFAMPIN, GRISEOFULVIN, anticonvulsants, sedative/hypnotics
decreased effectiveness of the oral contraceptives
use a back up for the ENTIRE PACK

decreased enterohepatic recirculation:
broad spectrum antibiotics kill the friendly "bacteria"
use a back up method while on the antibiotic AND 7 days after the completion of the antibiotic!

anticoagulant interaction:
increases clotting factors
INR will go down, may have to increase the warfarin dose
Term
what to do when a pill is missed
Definition
MISSED 1 DOSE:
take as soon as remembered or take 2 tablets the next day

MISSED 2 IN WEEK 1 OR 2:
take 2 tablets as soon as remembered or take 2 tablets the next 2 days
an additional method of contraception should be used for 7 days after missed dose

MISSED 2 IN WEEK 3:
continue dose of 1 tablet per day until Sunday, then discard the rest of pack, and start a new pack that same day
OR
current pack should be discarded and new pack should be started that same day
an additional method of contraception should be used for 7 days after missed dose

MISSED 2 (PROGESTIN ONLY):
take one of the missed doses, discard the other, and take daily dose at usual time

MISSED 3 OR MORE:
continue dose of 1 tablet daily until Sunday, then discard the rest of pack, and start a new pack that same day
OR
current pack should be discarded, and a new pack should be started that same day
an additional method of contraception should be used for 7 days after missed dose

MISSED 3 OR MORE (PROGESTIN ONLY):
current pack should be discarded
use another form of birth control until menses appears or pregnancy is ruled out
Term
additional indications for oral contraceptives
Definition
COC/POP induced improvements in menstrual symptoms:
fewer cramps/less pain
less flow or fewer days
more predictable menses
elimination of ovulation pain

non-contraceptive benefits of COC (other COC indications):

pelvic inflammatory disease - infection of the uterus, fallopian tubes, and other reproductive organs of the female reproductive system; usually caused by STD (chlamydia, gonorrhea); causes severe cramping; COC can help with the pain of PID

premenstrual dysphoric disorder (PMDD) - more severe PMS; moodiness is very severe, depression, cry uncontrollably, social isolation, suicidal ideation

dysmenorrhea/menorrhagia - heavy periods, irregular periods; taking COC will decrease period flow and make periods more predictable

endometriosis - lining of the endometrium is inflamed causing severe cramping; taking COC decrease the build up of the lining and decrease pain

polycystic ovarian syndrome (PCOS) - multiple cysts on the ovaries, can cause severe cramping; taking COC will decrease the cramping

acne vulgaris - certain products are proven to make acne better; contain LOW androgen component to decrease acne; acne is improved in many women by using estrogen-dominant, low androgen COCs; brand names include: Ortho Tri-Cyclen, Estrostep, Yasmin, Yaz
Term
COCs and cancer
Definition
ovarian:
risk decreased by 50% after 5 years
lasts for 10-20 years after pill is DC'd

endometrial:
same as ovarian

breast:
controverisal
strong family history of gene must be considered
Term
Yasmin clinical pearls
Definition
Yasmin = 3 mg drosperinone/30 mcg EE

first COC in US to contain drosperinone

drosperinone is a synthetic sprionolactone analog

indicated for acne

monophasic:
3 mg drosperinone and 30 mcg EE per tablet
21 active yellow tabs; 7 inert white tabs per cycle

take at the same time each day

initiate therapy on day 1 of menstrual cycle or first Sunday after start of menstrual cycle or quick start

drosperinone:
its anti-mineralocorticoid activity counteracts the aldosterone-stimulating effects of estrogens
estrogen-induced Na and water retention is reduced -> less increase in blood pressure, less weight gain
more favorable effects on HDL and LDL than other progestins
potential for hyperkalemia
Term
YAZ clinical pearls
Definition
YAZ = 3 mg drosperinon/20 mcg EE

indicated for PMDD and acne

contains drosperinone like Yasmin

24/4 dosing regimen (extended):
24 days of hormone containing tablets and 4 days of placebo
shorter bleed time
decreased PMS, decreased cramping
Term
meds to avoid (or use with caution and proper monitoring) while taking Yasmin or Yaz
Definition
ACE inhibitors
ARBs
K sparing diuretics
K supplements
aldosterone antagonists
NSAIDs

not contraindicated, but have to monitor K levels
Term
Loestrin 24 Fe clinical pearls
Definition
24 active "white" pills

take for week 1, 2, 3 and 1st part of week 4

4 brown pills containing iron

shorter, lighter periods without blood tests (no potassium monitoring)
Term
Femcon Fe clinical pearls
Definition
1st chewable birth control approved by FDA May 2006

may be chewed, followed by full glass of water OR swallowed whole

21 active + 7 reminders

all 7 pills contain 75 mg of ferrous fumarate
Term
Beyaz clinical pearls
Definition
Beyaz = drospirenone/EE/levomefolate calcium

28 day pack:
drospirenone/EE/levomefolate x 24 days
levomefolate x 4 days

levomefolate is a metabolite of folic acid

folic acid is to prevent neural tube defects that can occur in babies of mothers with low folic acid levels

all women of child bearing age should be taking folic acid as a supplement
Term
Seasonale clinical pearls
Definition
monophasic COC:
0.15 mg levonorgestrel
30 mcg EE

91 day regimen:
84 active pills followed by 7 inactive pills

women will get a period 4 times a year

Seasonale has more incidence of break through bleeding
Term
Seasonique clinical pearls
Definition
same 4 periods/year as Seasonale

levonorgestrel 0.15 mg and 30 mcg EE (84 days), 10 mcg EE (7 days)

proposed less break through bleeding with Seasonique
Term
Lybrel clinical pearls
Definition
Lybrel = 90 mcg levonorgestrel/20 mcg EE

1st and only low dose COC taken 365 days of the year

no scheduled menstrual period

high incidence of breakthrough bleeding or spotting (esp. during first 3 months of use)
Term
Ortho Evra clinical pearls
Definition
weekly transdermal patch

apply one patch weekly for 3 weeks
week 4 patch free
apply same day each week

apply to clean, dry skin,
BUTTOCK
ABDOMEN
UPPER OUTER ARM
UPPER TORSO (BACK)

fold prior to disposal, don't flush

rotate areas the patch is applied
at the beginning of each cycle can apply to the same area again

can alternate to different areas of the body

extra adhesive can be removed with baby oil

same CI/efficacy as OCP
time of day patch is changed does not matter

each patch will suppress ovulation up to 9 days
if it has been no more than 9 days since the patch was changed it is okay
if it has been more than 9 days they should put on a new patch and use back up for 7 days
if it has been more than 7 days since they have put on a patch, put one on and use backup for 7 days

new patch start day if more than a week between patches

starting the patch:
first day within 24 hours of menses
OR
Sunday after menses, even if not finished, need 7 day back up

label warnings:
60% higher systemic estrogen exposure; AUC greater
higher steady state and 25% lower peak concentration (compared to 35 mcg EE OCP)
increases risk associated with estrogen - clotting, VTE

ortho evra and body weight:
less effective in women who weight >/= 198 lbs (90 kg)
enhanced metabolic clearance rate in women > 90 kg
increased absorption of hormones into body fat = decreased absorption of the hormones into the circulation (longer time to reach steady state)
ortho evra is not recommended in patients weighting > 90 kg
Term
NuvaRing vaginal clinical pearls
Definition
flexible, combined hormonal ring

same CI/efficacy as OCP

insert ring for 21 days, 7 days ring free

FIRST TIME USER:
insert between days 1-5 of menstrual cycle
if inserted days 2-5 need 7 day back up

increased compliance

may store at room temperature, avoid extreme heat for up to 4 months

provides protection for up to 35 days
if it has been more than 35 days since inserted, take it out and start a new ring; use backup for 7 days

dispose in trash can

cannot be out for more than 3 hours a day
if > 3 hours during week 1 or 2 reinsert and use back up for 7 days
Term
estrogen AUC comparison
Definition
NuvaRing 10.6 +/- 2.5

COC oral 21.9 +/- 2.9

Ortho Evra 35.8 +/- 5.5

NuvaRing has the lowest AUC of estrogen; the patch as the highest estrogen AUC

when someone is stopping NuvaRing to get pregnant it usually happens faster than those taking the patch

KNOW WHAT HAS THE LOWEST ESTROGEN AUC
Term
Depo-Provera IM injection clinical pearls
Definition
medroxyprogesterone acetate

MOA:
inhibits ovulation
thickens cervical mucus
thins endometrial lining

dosage regimen:
150 mg deep IM injection in upper arm or buttock every 12 weeks (2 week grace period)
for 1st injection, give withing the 1st 5 days of cycle if not breastfeeding, if not use back up for 7 days

for breastfeeding women it has to be at least 6 weeks postpartum

side effects:
unpredictable bleeding
weight gain - 20 lbs weight gain in 3 months is average; more weight gain in women who are not obese
decreased bone mineral density (black box warning)
depression
unpredictable bleeding that may never decrease

effectiveness:
depends on patient's compliance
with good compliance can be just as effective as COC even though it only contains progesterone
Term
discontinuing oral contraceptives/return of fertility
Definition
average ovulation delay = 1-2 weeks

Depo-Provera can take up to 18 months (should not be used in a patient that wants to get pregnant soon)
Term
intrauterine contraceptives
Definition
"reversible sterilization"

immediate return of fertility after removal

1) Mirena - levonorgestrol releasing
plastic, flexible device inserted in uterus
inserted within 7 days of menses onset OR 6 weeks postpartum
provides protection up to 5 years
lighter periods or none
uterine cramps, bleeding
MD check placement 1-3 months after insertion and annually
the only patients that this product was studied in where those who have had at least one child
rare complication: can go through the uterus
if someone was to get pregnant on Mirena they are at risk for ectopic pregnancy (progesterone component); can burst the fallopian tube

2) Paraguard - copper releasing
prevents sperm from reaching and fertilizing the egg
no hormones avoids weight gain and mood swings
Term
2 types of emergency contraceptive pills
Definition
combined oral contraceptive pills (COCs)
YUZPE method: have to take 4-5 pills to get enough progestin component to prevent pregnancy; at the same time you are getting a lot of estrogen (causes a lot of ADRs - nausea, headache, vomiting, clotting); not FDA approved

progestin-only contraceptive pills (POPs)
most common
ex) Plan B
Term
common myths about EC
Definition
abortifacient: FALSE
harms developing fetus: FALSE

prevents or delays ovulation
prevents pregnancy from occurring

if pregnancy has occurred it will not harm the fetus

EC prevents implantation by delaying or preventing ovulation
Term
MOA of EC
Definition
PREVENT PREGNANCY

not an abortifacient, does not disrupt an implanted pregnancy

if taken before ovulation, EC disrupts normal follicular development and maturation, blocks LH surge, inhibits ovulation

alter endometrium to help inhibit implantation (proposed)

may affect tubal transport of sperm or ova if taken after ovulation (proposed)

works the best if taken before ovulation

will not disrupt a current pregnancy
Term
Plan B emercency kit clinical pearls
Definition
2 white tablets of levonorgestrel 0.75 mg (each)

1 tablet within 72 hours of unprotected sex then 1 tablet 12 hours later

may take both at the same time

stops 89% of pregnancy if taken within 72 hours

95% if used within 24 hours

effectiveness is greater the sooner it is taken

Plan B is available without prescription for patients 17 years or older

prescription required for patients 16 years old and younger

DOES NOT WORK IF PREGNANT

prevents or disrupts ovulation and fertilization

NOT effective once fertilization or implantation occurs

Patient Education:
may notice changes in menstrual bleeding after taking Plan B
if menses is delayed more than 1 week, pregnancy should be suspected

common ADRs:
nausea, abdominal pain, fatigue, headache, menstrual changes, dizziness, breast tenderness, vomiting and diarrhea
if they vomit within 2 hours, should take another pill
Term
One-step Plan B clinical pearls
Definition
levonorgestrel 1.5 mg

take within 72 hours of unprotected sex

same SE as 2 step Plan B
Term
Ella clinical pearls
Definition
ulipristal acetate 30 mg

progesterone agonist/antagonist
selective progesterone receptor modulator (SPRM)

delays or inhibits ovulation

can prevent pregnancy up to 120 hours after intercourse

same SE as Plan B

when taken before the LH surge ovulation is delayed by 5 days in 100% of women; when taken after the LH surge ovulation is delayed in 8% of women

overall, 60% effectiveness

after 72 hours with Ella the effectiveness is the same as at 24 hours
Term
COCs as EC
Definition
~20 different COCs that can be used as EC

take 1st dose withint 72 hours, then follow with 2nd dose 12 hours later

nausea (~50%); vomiting (~19%)
may pre-treat with antiemetic

NOT RECOMMENDED!!
Term
best choice for ECs
Definition
levonorgestrel vs. COCs

levonorgestrel more effective
levonorgestrel less side effects (no estrogen)

Plan B is the better choice!!
Term
when in cycle should EC be offered?
Definition
at any time during the cycle

worry about effectiveness of Ella in the 2nd half of the cycle
Term
how many times a year can a women use ECPs?
Definition
no limit
Term
if patient is pregnancy, will EC affect the fetus or pregnancy?
Definition
no, the hCG will overtake the other hormones
Term
starting contraceptives after EC use
Definition
should start regular method immediately

COCs: may start next day with 7 day backup method or wait for next menses

POPs: start on 1st day of menses

start barrier methods immediately, if preferred method

Ella: when restarting contraceptives (since it is a PR antagonist) there could be competition; the hormonal contraceptive could have decreased effectiveness (use 7 day backup no matter when they start!)
Term
pharmacist's right to refuse
Definition
the Health Care Right of Conscience Act states that not all people have the same moral or religious beliefs about what actions are medically acceptable and therefore issues state policy that Illinois will protect the right of conscience for any person who refuses to deliver, dispense, or pay for , or arrange a medical procedure, device, or other medical service if it conflicts with their personal moral or religious beliefs
Term
Sexual Assault Survivors Emergency Treatment Act of Illinois
Definition
hospitals must have approved plan for sexual assault victims

oral and written information about EC
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