Term
| What is the differential diagnosis of a pigmented skin lesion? (9) |
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Definition
melanoma
cafe au lait spots
Peutz Jeghers
Nevus
Freckle (ephelis)
Hemorrhage
Granulation tissue
Angioma
Lentigo |
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Term
| What skin characteristic are freckles and melanomas common in? |
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Definition
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Term
| Which type of pigmented lesion will change color in the sun? |
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Definition
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Term
| Which type of pigmented lesion has an increase in melanocytes? |
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Definition
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Term
| What is the medical term for a mole? |
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Definition
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Term
| Wat is the medical term for a freckle? |
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Definition
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Term
| What genetic mutation is seen in a nevus? |
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Definition
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Term
What is the shape of a junctional nevus?
Where are they located? |
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Definition
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Term
| Where is a compound nevus located in the skin? |
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Definition
| between the epidermis and dermis |
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Term
| Where is an intradermal nevus located? |
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Definition
| in the dermis (of course) |
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Term
Which type of malignancy is due to intermitant sun exposure?
Which two are more associated with extended exposure? |
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Definition
melanoma
sqaumous cell and basal cell carcinomas |
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Term
What genetic loss accompanies melanoma?
What does this mutation lead to? |
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Definition
E-cadherin
signals it to invade |
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Term
| What is a dysplastic nevi? |
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Definition
| a premalignant lesion worse than a nevus |
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Term
| What makes hemorrhage, granulation tissue, and angioma be put at the bottom of the diffential when the dx is likely melanoma? |
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Definition
| hemorrhage, granulation tissue, and angioma go away |
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Term
| What is Peutz Jeghers associated with? |
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Definition
GI tract involvement
lentigo like macules on lips |
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Term
| What layer of the epidermis is involved with in a lentigo? |
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Definition
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Term
What are the four types of melanomas?
Which is most common? |
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Definition
lentigo
superficial spreading (most common)
Acral melanoma
Nodular |
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Term
| What is a Hutchenson's Freckle? |
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Definition
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Term
| Where do lentigo maligna often effect anatomically on the body? |
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Definition
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Term
What is the prognosis of a nodular or Acral melanoma?
For each, why? |
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Definition
bad
nodular bad prognosis b/c verticle growth
acral bad prognosis b/c often caught late due to locatoin of incidence |
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Term
| Where do acral melanomas effect the body? |
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Definition
under the nails
palms
sole |
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Term
| What races are Acrul melanomas most common in? |
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Definition
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Term
| What scale is used most commonly to evaluate depth of a melanoma? |
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Definition
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Term
| In Breslow thickness what is the number that cuts off a thin melanoma which is curable to a more difficult melanoma? |
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Definition
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Term
| What is the gold standard treatment for melanoma? |
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Definition
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Term
| What melanoma chemotherapy drug is the only one FDA approved? |
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Definition
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