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sepration function selectively permeable controls what goes in and out |
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phospholipid by-layer embedded with proteins |
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singer fluid mosiac model |
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The cell membrane consists primarily of a thin layer of amphipathic phospholipids which spontaneously arrange so that the hydrophobic "tail" regions are shielded from the surrounding polar fluid, causing the more hydrophilic "head" regions to associate with the cytosolic and extracellular faces of the resulting bilayer |
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-temp. -unsaturation- unsaturated FA changes to help maintain fluidity. |
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4 major membrane phospholipids |
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1) phosphatidyl ethanomaline 2) phosphatidyl serine- carries negative charge 3) phosphatidyl choline- most common 4) sphingomyline-serine derivative- long acyl chain with an amino group |
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1molecule of cholesterol per phospholipid -vital component of cell membrane -stabilizes bilayer steroid rings stiffen structure |
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spherical vessicles in the membrane |
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1. LATERAL DIFFUSION- lipid diffuses lengthwise - travel w/in plane of membrane 2. FLEXION-bending interaction 3. ROTATION- turning in place 4. FLIPPING- move from 1 monolayer to another.-very rare. |
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5% of lipids in outter layer are glycosolated |
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electrical cond. cell-cell-recognition receptor function protect against LOW PH & DEGRADATIVE ENZ. |
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