Term
|
Definition
|
|
Term
|
Definition
| Inhibits reabsorption of water (increases urine flow) |
|
|
Term
|
Definition
Edema
HA/N/V
Fluid/electrolyte imballance may occure |
|
|
Term
|
Definition
| HF patients (risk for edema related complications) |
|
|
Term
|
Definition
Increases dopamine.
Effects diminish over time.
Takes several months to achieve full benefits.
Extremely effective - question if PT does not respond |
|
|
Term
|
Definition
N/V (Low initial dose, may take w/foods but avoid if possible)
Dyskinesia (reduce dosage/administer amantidine
Hpyotenstion (Increase water and salt intake)
Psychosis (reduce dose, antipsychotic med)
Insomnia/nightmares
Darken sweat/urine |
|
|
Term
|
Definition
| Enhance effects of Levodopa. |
|
|
Term
|
Definition
| Abnormal movements and psychiatric disturbances may occure sooner. |
|
|
Term
| Dopamine agonist - 1st choice for |
|
Definition
|
|
Term
| Mirapex (Pramipexole) class |
|
Definition
|
|
Term
|
Definition
N/DI/Constipation
Insomnia
Weakness
Hallucinations
Daytime solumnence
Sleep attacks
Impulse control disorders (caution hx of) |
|
|
Term
|
Definition
Several weeks.
Improve motor performance. |
|
|
Term
| COMT inhibitors (Comtan) MOA |
|
Definition
| Prolongs time levodopa is available in brain |
|
|
Term
|
Definition
Dyskinesias
O. HTN
N/V/DI/Constipation
Sleep disturbances
Hallucinations
Impulse control disorders
Yellow/orange discoloration of urine |
|
|
Term
| MAO-B inhibitors (selegline) MOA |
|
Definition
Inhibit the enzyme that inactivated dopamine (increases levels)
MAY delay progression Irreversible |
|
|
Term
| MAO-B Inhibitors (Selgline) AA |
|
Definition
Insomnia (last dose at noon)
Riak of hypertensive crisis |
|
|
Term
| MAO-B inhibitors (Selegline) Interactions |
|
Definition
Levodopa increases unwanted effects
SSRIs |
|
|
Term
| Centrally acting Anticholinergics |
|
Definition
Improve ballance between ach/dopamine.
Reduce rigidity and tremor but not bradycardia. |
|
|
Term
| Centrally acting anticholinergics AA |
|
Definition
Dry mouth
Blurred vision
Photophobia
Urinary retention
Constipation
Tacycardia
Monitor IOP (caution with glaucoma pts) |
|
|
Term
|
Definition
Low TI (toxicity risk)
Not for pregnancy
Mood stabilizing drug |
|
|
Term
| How often to monitor blood levels of lithium |
|
Definition
Every 2-3 days at start
Q3-6 months for maintainance |
|
|
Term
| Lithium toxicity risk is increased when.... |
|
Definition
Na is low.
Excretion is reduced when NA is low. Accumulates in body.
Catution with diuretics. |
|
|
Term
| Lithium excessive drug level AA |
|
Definition
Hand tremor
GI upset
Thirst
Muscle weakness |
|
|
Term
| Lithium AA therapeutic range |
|
Definition
GI affects (reduce with time)
Fatigue
Weakness
Polyuria/thirst
Renal toxicity!
Hypothyroidism |
|
|
Term
|
Definition
Diuretics
NSAINDS
Anticholinergics |
|
|
Term
|
Definition
-etine
Fluoxetine, Paroxetine.... |
|
|
Term
|
Definition
Sexual dysfunction
HA/N
Hyponatremia
Insomnia or anxiety
Weight gain after initial weight loss |
|
|
Term
|
Definition
|
|
Term
|
Definition
Ha/N
Anorexia
Sweating
Nervousness
Insomnia
Hyponatremia
May increase IOP (glaucoma caution)
May cause HTN (monitor BP) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
Suppresses appetite
Seiizures
Tremors
Dry mouth
Constipation
Tacycardia
DI/GI upset
No adverse sexual affects |
|
|
Term
|
Definition
|
|
Term
|
Definition
| Block reputable of NE and 5-HT |
|
|
Term
|
Definition
O. HTN
Anticholinergic effects
Diaphoresis
Sedation
Cardiac toxicity |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
CNS stimulation
O. HTN
Avoid Tyramines
Avocado, soy, cheeses, yeasts, fermented meats.... |
|
|
