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medications effect on sleep
sleep
23
Health Care
Not Applicable
07/04/2011

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Cards

Term
Hypnotics
Definition
all decrease sleep latency
Term
hypnotic
Definition
barbiturates
benzodiazepines
non-benzodiazepines
Term
barbiturates
Definition
Increase TST, REM suppression- increased REM latency, may increase sleep spindles, may increase slow wave sleep, decreased WASO
Term
Benzodiazepines
Definition
indicated for insomnia/ short term treatment
Term
Benzodiazepines effect on sleep
Definition
decrease arousalsand decrease WASO, Increase TST, Increase N1 and N2, increase fast EEG activity including spindles, may increase REM latency and dcrease total REM, decreases SWS and improves subjective sleep
Term
benzodiazepines
Definition
short-acting-(initiating sleep) Triazolan (Halcion),Temazepam (Restoril), Estazolam (Prosom)
Term
Benzodiazepines
Definition
long-acting(maintaining sleep) Fluazepam (Dalmane), Quazepam(Doral), Clonazepam(Klonopin), (may produce daytime sleepinesss)
Term
Non-Benzodiazepines
Definition
Zolipem(Ambien), Zalepon(Sonata)/ shor acting/rapid onset
Term
Non-Benzodiazepine
Definition
Lunesta- Rapid onset, Long acting/aproved for maintenance and long-term use
Term
Over the counter(OTC) substance (for sleep meds)
Definition
L-Tryptophan(amino acid)-may decrease sleep latency. Melatonin- decreases sleep latency, may decrease WASO, may produce daytime sleepiness and altered sleep patterns. Antihastamines- shortened sleep latency, REM suppression, daytime somnolence.
Term
Antidepressants
Definition
Tricyclics
MAOI-s
SSRI's
Term
Antidepressants
Definition
Tricycles- some sediating, moderate to strong REM suppression, generally increase TST, may increase PLMS
Term
Antidepressants
Definition
MAOI's- strong REM supresssion, decrease TST , and increase WASA
Term
Antidepressants
Definition
SSRI's- Lexapro, Prosac(Fluoxitine), Paxil(Paroxetine), Serazone,Wellbutrin(Buproprion), Trazadone(Desyrel)
Term
Antipressants
Definition
No effect on sleep onset,reduces SWS, may increase WASO, decrease REM(except Buproprin(Wellbutrin)), may worsen RLS, and may increase SREMS in NREM sleep.
Term
Antidepressants withdrawal effects
Definition
increase in WASO, intial decrease in REM latency and increase in REM %.
Term
Stimulants
Definition
Adderal, Amphetamines/Ritalin/Cylert/Cocaine, Theophylline, Decongestants, Nicotine, Caffeine
Term
Stimulants-effects on sleep
Definition
increase sleep latency, decrease TST, increase arousals and WASO, increase N1 and decrease SWS.
Term
Antiepileptics- Older drugs
Definition
phenobarbitol, sedation, increase sleep efficiency and decrease sleep latency.
Term
Antiepileptic newer drugs
Definition
gabapentin and neurontin
may increase SWS and REM
Term
alcohol effects on sleep
Definition
acute- increase TST in 1st half of night, increase WASO in 2nd half of night, decrease REM in 1st half of night and increase SWS.
Term
alcohol effect on sleep
Definition
chronic- decrease SWS
Term
alcohol withdrawal
Definition
decrease TST, increase WASO, increased REM and decreased SWS.
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