Term
Acute lymphocytic leukemia |
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Definition
Malignant, immature lymphocytes multiply in the blood, bone marrow, and lymphatic system. |
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Term
Acute myelogenous leukemia |
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Definition
Malignant, immature granulocytes called myeloblasts multiply in the bone marrow and bloodstream. |
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Abnormal condition of unequal size of cells (erythrocytes). |
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Protein made by white blood cells in response to foreign substances (antigens) in the blood. |
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A substance that works against coagulation (blood clotting). |
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Foreign agent that stimulates the production of an antibody. |
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Test for the presence of antibodies that coat and damage erythrocytes; Coombs test. |
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Withdrawal and separation of blood elements. |
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Failure of blood cell production due to aplasia (absence of formation) of bone marrow cells. |
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Removal and then reinfusion of a patient’s own blood or blood components. |
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base (alkaline, the opposite of acid) |
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White blood cell with dark-staining granules that have an affinity for basic dyes. |
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Orange-yellow pigment found in bile. It is released from the breakdown of hemoglobin when red blood cells die. |
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Time required for blood to stop flowing from a tiny puncture wound. |
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Blood cells or whole blood from a closely match donor are infused into a patient. |
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Needle aspiration of a small amount of bone marrow followed by examination under a microscope. |
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Term
Chronic lymphocytic leukemia |
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Definition
Malignant, but relatively mature lymphocytes, multiply in bone marrow, lymph nodes, and spleen. |
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Chronic myelogenous leukemia |
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Definition
Malignant, but relatively mature granulocytic leukocytes multiply in the bloodstream. |
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Process of blood clotting. |
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Time required for venous blood to clot in a test tube. |
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Disease of the clotting process |
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Term
Colony-stimulating factor |
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Definition
Protein that stimulates the growth and proliferation of white blood cells (granulocytes). |
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Definition
Determination of the number of red and white blood cells, platelets, hemoglobin, hematocrit, and red cell indices (MCH, MCV, MCHC) in a sample of blood. |
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abnormal condition of cells (increase in cells) |
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Specialization of cells from immature to mature forms. |
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Large blue or purplish patches on the skin (bruises). |
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Technique used to separate serum proteins by electrical charge. |
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White blood cell with dark-staining granules that have an affinity for acid dyes; granules turn red (eosin) in the presence of dye. |
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Definition
Increase in numbers of eosinophils. |
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Erythrocyte sedimentation rate |
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Definition
Measurement of the speed at which erythrocytes settle or fall to the bottom of a test tube. |
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Definition
Deficiency of red blood cells. |
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Definition
Formation of erythrocytes. |
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Protein threads that form the basis of a blood clot. |
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Plasma protein that is converted to fibrin in the clotting process. |
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Definition
pertaining to, produced in |
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Major blood proteins; immunoglobulins, alpha, beta and gamma globulins are examples. |
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White blood cell with large, dark-staining granules in its cytoplasm. |
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Deficiency of granulocytes (white blood cells). |
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Increased numbers of granulocytes in the blood. |
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Separation of blood; percentage of red blood cells in a given volume of blood. |
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Formation of blood cells. |
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Term
Hematopoietic stem cell transplant |
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Definition
Peripheral (found in the blood) stem cells from a compatible donor are administered into the vein of a recipient. |
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Excessive deposits of iron throughout the body. |
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Blood protein in erythrocytes; enables the cell to carry oxygen. |
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Total amount of hemoglobin in a sample of blood. |
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Disease of abnormal hemoglobins (sickle-cell anemia, thalassemia). |
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Destruction of blood cells. |
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Reduction in erythrocytes due to excessive destruction of red blood cells. |
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Hereditary disease of blood clotting failure with abnormal bleeding. Affected individuals are lacking a blood clotting factor (factor VIII or factor IX). |
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Stoppage of the flow of blood. |
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Anticoagulant found in blood and tissues. |
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Pertaining to deficiency of color (reduction of hemoglobin in red blood cells). |
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Response of the immune system to foreign invasion. |
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Protein (antibody produced by plasma cells) that acts to protect the body by destroying antigens. |
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Substance normally found in gastric (stomach) juice that helps absorption of vitamin B12 into the bloodstream. |
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Removal of white blood cells from the rest of the blood by centrifugation. |
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Abnormal condition of white blood cells (increase in numbers of malignant cells). |
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Deficiency of white blood cells. |
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White blood cell with a single nucleus (mononuclear); capable of producing antibodies. |
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pertaining to destruction |
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Abnormal condition (slight increase in numbers) of macrocytes (red blood cells that are larger than normal). |
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Large cell (in blood and tissues) that eats (engulfs) other cells; derived from a monocyte. |
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Cell with multiple large nuclei; immature platelet. |
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Abnormal condition (slight increase in numbers) of microcytes (red blood cells that are smaller than normal). |
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Immature white blood cell (monocyte). |
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White blood cell with one large nucleus; an agranulocyte and phagocyte. |
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Pertaining to a white blood cell with one large nucleus (monocyte or lymphocyte). |
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Infectious disease marked by increased numbers of leukocytes and enlarged cervical lymph nodes. |
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Study of shape or form (of blood cells). |
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Malignant tumor of bone marrow; overproduction of immunoglobulins and destruction of bone tissue. |
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Definition
Bone marrow cell that develops into a myelocyte and then a leukocyte. |
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Pertaining to formed in the bone marrow |
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Definition
Derived from bone marrow. |
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Definition
Formation of bone marrow. |
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nuetral (neither base nor acid) |
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Deficiency in neutrophils. |
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Definition
White blood cell with dark granules that stain with a neutral dye; phagocyte formed in the bone marrow and the body’s first line of defense against disease. |
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Increase in numbers of neutrophils. |
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Relieving, but not curing illness. |
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Deficiency of all (blood) cells. |
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Partial thromboplastin time |
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Definition
Measurement of presence of plasma factors that act in a portion of the coagulation pathway. |
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Lack of mature erythrocytes caused by inability to absorb vitamin B12 into the body. |
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Small, pinpoint hemorrhages caused by bleeding under the skin. |
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Cell that ingests other cells or microorganisms. |
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attraction for (an increase in cell numbers) |
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Liquid portion of blood containing proteins, water, salts, nutrients, hormones and vitamins. |
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Removal of plasma from the rest of the blood by mechanical means (centrifuge). |
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Clotting cell or thrombocyte. |
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Number of platelets per cubic millimeter (mm3 ) or microliter ( L) of blood. |
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Removal of platelets from the rest of the blood by centrifugation. |
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Irregularity in the shape of red blood cells. |
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Definition
Increase in numbers of red blood cells (erythremia). |
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Pertaining to a white blood cell with a multilobed nucleus (neutrophil). |
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Plasma protein converted to thrombin in the clotting process. |
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Test of the ability of blood to clot. |
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Multiple pinpoint hemorrhages and accumulation of blood under the skin caused by deficiency of clotting cells (platelets). |
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Number of erythrocytes per cubic millimeter or microliter of blood. |
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Red blood cell morphology |
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Definition
Microscopic examination of a stained blood smear to determine the shape of individual red blood cells. |
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Return of symptoms of disease. |
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Disappearance of symptoms of disease. |
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Immature erythrocyte with a network of strands (reticulum). |
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Antigen (protein) on red blood cells of Rh positive individuals. |
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Plasma minus clotting proteins (prothrombin and fibrinogen) and clotting cells. |
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Hereditary condition marked by abnormal sickle shape of erythrocytes and by hemolysis. |
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Deficiency in iron in serum. |
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Increase in numbers of sphere-shaped red blood cells, as in a type of anemia (hemolytic anemia). |
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Unspecialized cell that gives rise to all forms of specialized cells in the body. Hematopoietic stem cells are found in the bone marrow and lead to the development of all types of blood cells. |
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Inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean background. |
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Enzyme necessary for blood clotting (converts fibrinogen to fibrin in the clotting process). |
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Deficiency of clotting cells. |
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Definition
Treatment that destroys blood clots. |
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Definition
Abnormal condition of clotting. |
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Definition
Number of leukocytes per cubic millimeter or microliter of blood. |
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Term
White blood cell differential |
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Definition
Percentage of the total white blood cell count made up by different types of leukocytes. |
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