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Lesson 10: Endocrinology
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03/30/2009

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Term
PITUITARY GLAND (HYPOPHYSIS)
Definition
Gland situated on the under-surface of the brain. Consists of two distinct masses of endocrine tissue.
Term
ADENOHYPOPHYSIS
Definition
The anterior pituitary; produces hormones that regulate the development and function of other endocrine glands.
Term
THYROID-STIMULATING HORMONE (TSH)
Definition
A hormone produced by the adenohypophysis that regulates thyroid function.
Term
ADRENOCORTICOTROPIC HORMONE (ACTH)
Definition
Hormone produced by the adenohypophysis that stimulates the adrenal cortex.
Term
FOLLICLE-STIMULATING HORMONE (FSH)
Definition
Hormone produced by the adenohypophysis that stimulates gonadal function.
Term
LUTEINIZING HORMONE (LH)
Definition
Hormone produced by the adenohypophysis that stimulates gonadal function.
Term
GROWTH HORMONE (SOMATOTROPIN)
Definition
Hormone produced in the adenohypophysis that regulates the natural growth process.
Term
PROLACTIN
Definition
Hormone produced by the adenohypophysis that is required for lactation after pregnancy.
Term
NEUROHYPOPHYSIS
Definition
The posterior pituitary; is in direct continuity with the hypothalmus.
Term
HYPOTHALAMUS
Definition
Links the nervous system to the endocrine system via the pituitary.
Term
OXYTOCIN
Definition
Hormone produced by the hypothalamus that stimulates uterine contractions in labor.
Term
VASOPRESSIN (ANTIDIURETIC HORMONE, ADH)
Definition
Hormone produced in the hypothalamus that helps to control water balance by promoting reabsorption of water by kidneys.
Term
THYROID GLAND
Definition
Gland situated in the front of the neck overlying the junction of the larynx and trachea. The hormones produced by the thyroid gland circulate in the blood to influence general metabolism.
Term
THYROXINE (T4)
Definition
An iodine-containing hormone produced by the thyroid gland that circulates in the blood by binding to a plasma protein.
Term
TRI-IODOTHYRONINE (T3)
Definition
An iodine-containing hormone produced by the thyroid gland that circulates in the blood by binding to a plasma protein.
Term
THYROID BINDING GLOBULIN (TBG)
Definition
Hormones that circulate by binding to plasma proteins.
Term
PARATHYROID GLANDS
Definition
Named because they lay in or on the capsule of the thyroid gland.
Term
PARATHYROID HORMONE (PTH)
Definition
Hormone produced by the parathyroid glands that regulates the serum calcium level within narrow limits.
Term
CALCITONIN
Definition
Hormone produced by the thyroid gland that is involved in regulation of serum calcium.
Term
ADRENAL GLANDS
Definition
Two crescent-shaped caps of endocrine tissue, one situated on top of each kidney.
Term
CORTEX
Definition
The outer layer of endocrine tissue on the adrenal glands.
Term
MEDULLA
Definition
The inner layer of endocrine tissue of the adrenal glands.
Term
GLUCOCORTICOIDS
Definition
Produced by the adrenal cortex. Increase glucose production by the liver, affect protein and fat metabolism, help to regulate blood pressure, mediate many of the responses of the body to stress, and tend to supress immune and inflammatory responses.
Term
MINERALOCORTICOIDS
Definition
Produced by the adrenal cortex. Regulate electrolyte and water balance by promoting renal retention of sodium ions of potassium, hydrogen, and ammonium ions.
Term
ADRENAL ANDROGENS
Definition
Produced by the adrenal cortex. These play a minor role in reproductive physiology in both men and women.
Term
ISLETS OF LANGERHANS
Definition
Tiny aggregations of endocrine cells that carry out the endocrine functions of the pancreas.
Term
B OR BETA CELLS
Definition
Cells of the islets of Langerhans that produce insulin, which increases glucose utilization and exerts other complex influences on the metabolism of carbohydrates, proteins, and fats.
Term
A OR ALPHA CELLS
Definition
Cells of the islets of Langerhans that produce glucagon, an inhibitor of glucose activity.
Term
D OR DELTA CELLS
Definition
Cells of the islets of Langerhans that produce somatostatin, which inhibits secretion of growth hormone by the anterior pituitary.
Term
ACROMEGALY
Definition
Abnormal growth of the body, especially facial features and extremities due to excess of pituitary growth hormone.
Term
ALOPECIA
Definition
Hair loss
Term
AMINO ACID
Definition
A relatively simple nitrogen-containing organic compound. Of the 20 amino acids that are essential to human metabolism, half can be manufactured in the body and the others must be obtained in the diet.
Term
BODY MASS INDEX (BMI)
Definition
A measure of the proportion of fat to lean body mass.
Term
BRUIT
Definition
A vascular hum synchronous with heartbeat, heard with a stethoscope.
Term
CALORIE
Definition
A measurement of the energy released by food.
Term
CARBOHYDRATE
Definition
One of three basic food types, it is the source of energy in the diet which is consumed in the form of starches and sugars.
Term
CORTICOSTEROID
Definition
Cortisol or aldosterone (hormones of the adrenal cortex), or any synthetic drug having similar effects.
Term
DIAPHORESIS
Definition
Sweating
Term
ENDOCRINE GLAND
Definition
A gland that secretes internally (directly into the circulation): pituitary, thyroid, adrenal, pancreas, gonads.
Term
ESSENTIAL AMINO ACIDS
Definition
Amino acids that cannot be made in the body and must be obtained from diet.
Term
EUTHYROID
Definition
Normal thyroid
Term
EXOPHTHALMOS
Definition
Bulging or protrusion of one or both eyes
Term
FAT
Definition
One of three basic food types, also called lipid. It is an oily or greasy substance built up of fatty acids (long, straight-chain organic acids).
Term
GLUCOSE
Definition
A 6-carbon sugar that is the most plentiful in the blood and the principal fuel of cellular energy metabolism.
Term
GOITER
Definition
Enlarged thyroid gland
Term
HORMONE
Definition
Chemical messenger or mediator produced by a cell, tissue, or gland.
Term
HYPERGLYCEMIA
Definition
Elevated blood glucose
Term
HYPOGLYCEMIA
Definition
Low level of blood glucose
Term
HYPERKALEMIA
Definition
Elevation of serum potassium
Term
KETOACIDOSIS, DIABETIC
Definition
Accumulation of ketone bodies in the body tissues and fluids from abnormal metabolization of fat.
Term
LID LAG
Definition
Slowness of upper eyelids to move with eye movements.
Term
LIPID
Definition
Fat
Term
MYXEDEMA
Definition
Abnormal swelling of the skin due to deficiency of thyroid hormone.
Term
NUTRITION
Definition
The intake and use of foods by the body.
Term
POLYDIPSIA
Definition
Excessive thirst
Term
POLYPHAGIA
Definition
Excessive hunger
Term
POLYURIA
Definition
Excessive urination
Term
POST PRANDIAL
Definition
After meals
Term
PROTEIN
Definition
One of three basic food types, made up of long strands of amino acids, proteins are responsible for maintenance and repair of tissues and organs, and for production of intracellular enzymes, hormones, and other substances.
Term
PTOSIS
Definition
Sagging
Term
SELLA TURCICA
Definition
The saddle-shaped bony depression in which the pituitary rests.
Term
RELEASING HORMONE
Definition
Promotes release of a specific hormone into the circulation.
Term
SOMATOSTATIN
Definition
A hormone that inhibits production and release of growth hormone.
Term
TROPIC HORMONE
Definition
Stimulates the cells of a remote gland to produce its secretion.
Term
VITAMIN
Definition
An organic compound normally present in many foods that the human body needs in trace amounts, usually to serve as boosters or catalysts in essential metabolic processes.
Term
LOSING HAIR (LAY)
Definition
Alopecia
Term
SEX DRIVE (LAY)
Definition
Libido
Term
SUGAR DIABETES (LAY)
Definition
Diabetes mellitus
Term
SWEATING (LAY)
Definition
Diaphoresis
Term
CHVOSTEK TEST, SIGN
Definition
Twitching of the face after percussion over the facial nerve in front of the ear, a sign of latent tetany due to hypocalcemia
Term
FINE-NEEDLE BIOPSY OF THE THYROID GLAND
Definition
Sampling of the thyroid gland tissue via insertion of a fine-bore needle into the thyroid
Term
GLUCOMETER
Definition
A small portable device from Bayer used to measure blood sugar
Term
LOBECTOMY
Definition
Surgical removal of a lobe of the thyroid gland
Term
PARATHYROIDECTOMY
Definition
Surgical removal of one or more of the parathyroid glands
Term
TROUSSEAU TEST, SIGN
Definition
Spastic contraction of the hand after application of a constricting cuff to the arm, a sign of latent tetany
Term
THYROIDECTOMY
Definition
Surgical removal of the thyroid gland
Term
ACETONE, URINARY
Definition
Acetone in the urine can be measured with a dipstick. Small amounts are found in starvation and other abnormal metabolic states, larger amounts in uncontrolled diabetes mellitus
Term
BLOOD SUGAR
Definition
The level of glucose in the blood
Term
CALCITONIN, SERUM
Definition
A hormone produced by the thyroid gland and affecting the metabolism of calcium. It is markedly elevated in certain malignancies of the thyroid and lung
Term
FASTING BLOOD SUGAR (FBS)
Definition
Determination of serum glucose in a specimen drawn from a patient who has been fasting for several hours, usually overnight
Term
GLUCOSE TOLERANCE TEST (GTT)
Definition
Measurements of blood sugar made at various intervals after ingestion of a standard carbohydrate meal
Term
GLUCOSE, URINARY
Definition
Should be negative. Glucose (sugar) in the urine usually indicates diabetes mellitus or other endocrine dysfunction
Term
GLYCOSYLATED HEMOGLOBIN (HEMOGLOBIN A1C)
Definition
Measurement of the amount of glucose bound to the hemoglobin of red blood cells. Useful in monitoring long-term control of diabetes mellitus
Term
KETONES, SERUM
Definition
A group of waste products resulting from abnormal metabolism of fat in uncontrolled diabetes mellitus. Ketones may be called ketone bodies or simply "acetone."
Term
17-KETOSTEROIDS
Definition
Urinary breakdown products of adrenal cortical hormones, increased in certain disorders of the adrenal gland
Term
T3, T3, (TRIIODOTHYRONINE)
Definition
Thyroid hormone
Term
T4, T4 (THYROXINE)
Definition
Thyroid hormone
Term
THYROID-STIMULATING HORMONE (TSH)
Definition
Hormone secreted by the anterior pituitary gland that stimulates the thyroid gland and promotes its normal function
Term
THYROXINE
Definition
Principal hormone of the thyroid gland. Also called T4.
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