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Medical Mycology III
Superficial, cutaneous and subcutaneous mycoses
37
Medical
Professional
04/15/2009

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Term
4 examples of superficial mycoses
Definition
tinea versicolor, tinea nigra, black piedra, white piedra
Term
significance of superficial mycoses
Definition
infections are only troublesome, not serious
Term
cutaneous mycoses caused by:
Definition
dermatophytes
Term
ringworm
Definition
dermatophytic infection
Term
description of cutaneous mycoses
Definition
filamentous fungi (moulds) theat live in all fully keratinized tissues; do not usually penetrate beneath epiderm
Term
3 genera of dermatophytes
Definition
microsporum, trichophyton, epidermophyton
Term
hair and scalp infection
Definition
tinea capitis
Term
endothrix infection
Definition
growth/sporulation within hair shaft
Term
ectothrix infection
Definition
growth/sporulation around hair shaft
Term
beard infection
Definition
tinea barbae
Term
eyebrows infection
Definition
kerion (suppurative folliculitis)
Term
big circular lesion so f smooth skin
Definition
tinea corporis
Term
jock-itch
Definition
tinea cruris
Term
athlete's foot
Definition
tinea pedis
Term
nails infection
Definition
tinea unguium
Term
treatment for dermatophytes
Definition
acute: desenex, tinactin
chronic: topical azoles
Term
lab ID methods for dermatophytes
Definition
1) collect skin/hair/nails
2) KOH prep for microscopy
3) culture on Sabourad dextrose agar or dermatophyte test media
Term
Macroconidia: abundant, club-shaped, thick-walled, smooth, arranged in groups
Microconidia: absent
Definition
Epidermophyton
Term
Macroconidia: usually abundant, spindle-shaped, thick-walled, rough
Microconidia: scarce, elongate
Definition
Microsporum
Term
Macroconidia: scarce, club-shaped, smooth, thin-walled
Microconidia: abundant, sperical/elongate/pear-shaped
Definition
Trichophyton
Term
Subcutaneous mycoses (4)
Definition
sporotrichosis, chromomycosis, eumycotic mycetoma, phaeohyphomycosis
Term
puncture wound followed by painless papules after 1-3 weeks, then spread distally along lymphatic channels
Definition
lymphocutaneous disease (sporotrichosis)
Term
Pulmonary sporotrichosis
Definition
rar but very serious form found in immunosuppressed
Term
sporotrichosis etiologic agent
Definition
sporothrix schenckii
Term
dimorphic fungus
tissue phase: cigar-shaped yeasts
mould phase: pyriform (means pear-shaped you twit) conidia in rosette clusters; turn white-to-black
Definition
sporothrix schenckii
Term
yeast forms surrounded by eosinophilic halo
Definition
asteroid bodies, represent deposition of Ag/Ab complexes; sporotrichosis
Term
infection of skin with painless, cauliflower-like lesions
Definition
chromomycosis
Term
etiologic agent of chromomycosis
Definition
slow growing dematiaceous (black) fungi; fonsecaea, cladosporium, exophiala, wangiella, phialophora
Term
brown segmented hyphal forms seen in infected tissues
Definition
Sclerotic bodies, diagnostic of chromomycosis
Term
soil implantation --> spreads through skin as far as bone --> forms granulomas and abscesses that drain into sinus tracts
Definition
eumycotic mycetoma; madura mycosis
Term
eumycotic mycetoma etilogic agents
Definition
pseudallescheria boydii, madurella mycetomatis
Term
"grains" found in sinus tract drainage; mouse-gray,lollipop candida on microscope
Definition
eumycotic mycetoma
Term
heterogenous array of fungal infections cuased by dematiaceous fungi commonly found in the environment
Definition
Phaeohyphomycosis
Term
present in tissues as pigmented irregular hyphal forms
Definition
Phaeohyphomycosis
Term
Subcutaneous disease presents as solitary cyst-like lesion secondary to traumatic implantation of contaminants
Definition
phaeohyphomycosis
Term
etiologic agents of phaeohyphomycosis
Definition
exophiala, wangiella, bipolaris
Term
treatment for phaeohyphamycosis
Definition
surgical excision
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