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Medical Microbiology chap 1-6
Exam 1, chaptesr 1-6 (Book the Microbial Challenge)
41
Biology
Undergraduate 4
02/01/2012

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Cards

Term
Characteristics of Microbes (ch 1)
Definition

1. Microscopic & single-celled (usually)

2. Essential to cycles of nature

3. Beneficial and even essential to human health

4. Capable of causing illness and/or death (minority)

Term
The five (6) categories of microbes (ch 1)
Definition

1. Bacteria

2. Viruses

3. Protozoa

4. Fungi

5. Algae

(6) Prions

Term
World Population Growth contributes to spread of infectious diseases by (ch 1)
Definition
having a higher density, allows more person to person, biological vectors and zoonontic encounters
Term
Because of ______ more of the world's population is becoming concentrated in cities.
Definition
Urbanization (ch 1)
Term
Deforestation causes _____ (ch 1)
Definition
increased contact with animals and insect vectors.
Term
Chagas disease, rabies & leishmaiasis are often caused because of ____
Definition
migration and displacement of animals and vectors into villages.
Term
Climatic changes cause
Definition
ecological disturbances that increase the incidence of distribution of infectious disease
Term
Pathogen
Definition
disease producing microbes 
Term
Nosocomial Infection
Definition
hosptial acquired infection
Term
Reasons for increase (or outbreaks) of infectious disease and an example of each.
Definition
Term

Characteristics of Prokaryotes

1. Types of Life forms

2. Does it have a nucleus?

3. Cell size

4. Type of Chromosome

5. Internal Compartments?

6. Ribosomes 

Definition
Term

Characteristics of Eukaryote

1. Types of Life forms

2. Does it have a nucleus?

3. Cell size.

4. Type of Chromosome

5. Internal Compartments?

6. Ribosomes? 

Definition

1. Protozans, plants, animals, fungi, algae

2. It has a nucleus

3. larger than prokaryotes, >100nanometers

4. Multi linear chromosome

5. Yes, membrane bound organelles

6. 40s, 60s

Term
Cell Theory
Definition

1. All organisms are composed of fundamental units called cells

2. all organisms are unicellular or multicellular

3. all cells are fundamentally alkike w/ regard to their structure and their metabolism

4. Cells arise from previous existing cells

Term
2 sources of nitrogen
Definition

1. bacteria

2. industry

Term
Why Harness Mircrobes in Research 
Definition

1. Easy to culture

2. small

3. short life cycle 

4. small genome sequence

5. gene therapy: Fix genetic defects by adding it back

Term
Biomediation
Definition
Adding materials/microorganisms to the environment to speed up natural biodegradation
Term
Bioaugmentation 
Definition
Enhancing bio-degradation by adding nutrients to increase indigenous microbes
Term
Bacillus
Definition
Rod shaped
Term
coccus
Definition
spherical 
Term
sprial or curved
Definition
spirilla or vibrio
Term
Envelope
Definition
is external to the cytoplasm
Term
Plasma membrane
Definition

selectively permable 

Cell was is G+ or G-

Term
The gram - only has
Definition
an outer membrane
Term
Capsule
Definition

not integral to the cell

is a virulence factor, anti-phagcytic 

Term
why is a gram stain important?
Definition

Choice of antibiotics influenced by the gram stain

Broad spectrum antibiotics work against G+ AND G-

Narrow spectrum antibiotics works against G+ OR G-

Term
Cytoplasm
Definition
Cells contents w/in the plasma membrane
Term
nucleoid
Definition

region of cytoplasm containing chromosome DNA

double stranded DNA

one or more circular and/or linear chromosomes

 

Term
plasmids
Definition

small circular pieces of DNA

encodes small # of genes

expands genetic apability

Term
spores
Definition

endospores formed w/in the cell

viable for long periods (Centuries)

resitant to heat, boiling, drying, radiation and various chemicals

 

Term
4 phases of binary fission in bacteria
Definition

1. lag phase

2. log phase

3. stationary phase

4. death phase

Term
Mycoplasma
Definition

have no cell wall, thus no shape

very small and require specialized media for growth

disease: walking pneumonia

Term
Chlamydiae
Definition

obligate intracellular parasite

disease: urethritis

Term
Rickettsiae
Definition

obligate intracellular parasite

transmitted by arthropods

Term
2 largest pandemics ever known caused by viruses
Definition

1918 spanish flu (killed more than 25 million)

&

HIV

Term
Viral Classification 
Definition

Structure

Host Cell

Clinical (organ or organ system)

Term
Virus life cycle (replication)
Definition

1. Adsorption

2. Replication

3. Assembly

4. Release

Term
Bacterial Conjugation
Definition

Requires cell to cell contact

donor requires F factor

Donors are F+, recipients F-

Term
Transformation 
Definition

Generates "competent" cells by some treatment to permeabilized the cell membrane

- chemical cometent

-electroporation

-generally restricted to plasmids

-power tool in lab study genetic engineering 

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