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Medical Microbiology 9-16
9-16 Intro
25
Microbiology
Professional
09/22/2010

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Term
Host =
Definition
person of other living organism that can be infected by agent under natural or experimental conditions
Term
Agent=
Definition
factor whose presence (too much, too little) or absence is essential to occurrence of disease.
Can be living or non living
Term
Environmental factors=
Definition
extrinsic factor which affects the agent and opportunity for exposure
Term
Transmission of Infection=
Definition
Any mode or mechanism that the infectious agent spreads through the environment or to another host.
Term
Locus=
Definition
site on or in the body where infection originates
Term
Name the large portals of entry in body and how pathogens would gain entry.
Definition
1) skin
2) respiratory mucosa
3) alimentary tract
4) genital tract
5) conjunctiva

1) infect cells of surface
2) breach surface by trauma
3) transmitted congenitally
Term
Horizontal Transmission=
Definition
infection transmission from one person to another of the same generation in population (anything that's NOT mother to newborn)
Term
Vertical Transmission=
Definition
from mother to newborn either by pregnancy, childbirth, or breastfeeding
Term
Contact Transmission=
Definition
exposure to source of infection
actually a form of Direct Transmission (object to host, host to host)
Term
Direct Transmission=
Definition
immediate transfer of agent from reservoir to host by direct contact or droplet spread
Term
Indirect Transmission=
Definition
agent carried from reservoir to a host by AIR PARTICLES, ANIMATE VECTOR, or INANIMATE VEHICLE intermediaries.
Term
Droplet Transmission=
Definition
direct transmission of agent from reservoir to host by spray with large, short-range aerosols
Range= less than 1 meter
Term
Droplet Nuclei=
Definition
residue to dried droplets that may remain in air and be blown over long distances.
Easily inhaled
Term
Vector Transmission=
Definition
Animate intermediary in indirect transmission of agent which carries agent from reservoir to host.
Term
Parenteral route=
Definition
administration that involves piercing the skin or mucous membrane
Term
Carrier Host=
Definition
person or animal with no apparent disease but can still give infectious agent to others.
Can be during an incubation period or host may not know.
Can be transient or chronic carrier
Term
Iatrogenesis=
Definition
artifact that refers to adverse effects/complications caused by medical treatment or advice.
Term
Infectivity=
Definition
proportion of persons exposed to causative agent WHO BECOME INFECTED.
Term
Zoonoses=
Definition
infectious disease transmissible under normal conditions from animals to humans
Term
Endemic disease
Definition
presence of disease within a geographic area or group.
Term
Epidemic=
Epidemic period=
Definition
= occurance of MORE cases of disease than expected in a given area/group over some period of time.
=time period when number of cases of disease is greater than expected.
Term
Pandemic=
Definition
=epidemic occurring over very wide area and affecting large proportion of population
Term
Name the three ways to classify disease transmission
Definition
1) Vertical vs Horizontal
2) Portal of Entry
3) Mode of Infection
Term
Fomite =
Definition
=inanimate object which transmits disease when there is contact with it. But it's not food or water.
Term
Airborne transmission=
Definition
= transmission of agent through the air via droplets that goes more than 1 meter from source or reservoir
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