Term
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Definition
Natural chemicals that exert their effects on specific tissues known as target tissues |
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Term
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Definition
Specific tissues affected by hormones |
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Term
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Definition
Hypothalamus Pituitary glands Adrenal glands Thyroid glands Islet cells of the pancreas Parathyroid glands Gonads |
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Neuroendocrine regulation |
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Definition
The endocrine and the nervous system work together to control overall body function |
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Definition
Constant normal balance of the body maintained in response to environmental changes |
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Term
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Definition
Corticotropin-releasing hormone (CRH) Thyrotropin-releasing hormone (TRH) Gonadotropin-releasing hormone (GnRH) Growth hormone-inhibiting hormone (somatostatin GHIH) Prolactin-inhibiting hormone (PIH) Melanocyte-inhibiting hormone (MIH) |
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Anterior pituitary hormones |
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Definition
Thyroid-stimulating hormone (TSH, thyrotropin) Adrenocorticotropic hormone (ACTH, corticotropin) Luteinizing hormone (LH, Leydig cell-stimulating hormone [LCSH]) Follicle-stimulating hormone (FSH) Prolactin (PRL) Growth hormone (GH) Melanocyte-stimulating hormone (MSH) |
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Posterior pituitary hormones |
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Definition
Vasopressin (anti-diuretic hormone [ADH]) Oxytocin |
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Definition
Triiodothyronine (T3) Thyroxine (T4) Calcitonin |
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Parathyroid hormone (PTH) |
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Glucocorticoids (cortisol) Mineralocorticoids (aldosterone) |
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Definition
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Definition
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Insulin Glucagon Somatostatin |
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Disorders of the endocrine system |
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Definition
Usually related to an excess/deficiency of a specific hormone, or a receptor defect. |
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Negative feedback control mechanism |
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Definition
The condition of maintaining a constant output of a system by exerting an inhibitory control on a key step by a product of that system. Used in a series of reactions that control hormone secretion and cellular activity based on responses to correct any movement away from normal function. An example of a simple negative feedback hormone response is the control of insulin secretion in which the action of insuling (decreasing blood glucose levels) is the opposite of the condition that stimulated insulin secretion (elevated blood glucose levels) |
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Hypothalamic-hypophysial portal system |
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Definition
Allows hormones produced in the hypothalamus to travel directly to the anterior pituitary gland so that only very small amounts are wasted in systemic circulation |
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Definition
The anterior lobe of the pituitary gland |
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Definition
The posterior lobe of the pituitary gland |
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Term
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Definition
Hormones secreted by the anterior pituitary that stimulate other endocrine glands |
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Term
Thyroid Stimulating hormone (TSH) |
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Definition
Anterior pituitary hormone that targets the thyroid. Stimulates synthesis and release of thyroid hormone |
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Term
Adrenocorticotropic hormone (ACTH) |
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Definition
Anterior pituitary hormone that targets the adrenal cortex. Stimulates synthesis and release of corticosteroids and adrenocortical growth. |
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Definition
Anterior pituitary hormone that targets the ovaries and testes. Stimulates either estrogen secretion and follicle maturation or spermatogenesis. |
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Follicle stimulating hormone (FSH) |
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Definition
Anterior pituitary hormone that targets the ovaries and testes. Stimulates either estrogen secretion and follicle maturation or spermatogenesis. |
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Definition
Anterior pituitary hormone that targets the mammary glands. Stimulates breast milk production. |
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Definition
Anterior pituitary hormone that targets bone and soft tissue. Promotes growth through lipolysis, protein anabolism, and insulin antagonism. |
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Term
Melanocyte-stimulating hormone (MSH) |
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Definition
Anterior pituitary hormone that targets melanocytes. Promotes pigmentation. |
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Definition
Posterior pituitary hormone that targets kidneys. Promotes water re-absorption. |
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Definition
Posterior pituitary hormone that targets the uterus and mammary glands. Stimulates uterine contractions and ejaculation of breast milk. |
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Definition
Male and female reproductive endocrine glands. Male - testes. Female - ovaries. |
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Term
Functions of glucocorticoid hormones |
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Definition
Prevent hypoglycemia by increasing liver gluconeogenesis and inhibiting peripheral glucose use. Maintain excitability and responsiveness of cardiac muscle. Increase lipolysis, releasing glycerol and free fatty acids. Increase protein catabolism. Degrade collagen and connective tissue. Increase the number of mature neutrophils released from bone marrow. Exert anti-inflammatory effects that decrease the migration of inflammatory cells to sites of injury. Maintain behavior and cognitive functions. |
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Definition
Hormones produced in the zona glomerulosa (located in the cortex) of the adrenal gland that help control the body's sodium and potassium content |
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Term
Adrenal steroids (corticosteroids) |
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Definition
Hormones secreted by the cortex of the adrenal gland |
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Structure of the adrenal gland |
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Definition
Capsule Cortex - Zona glomerulosa(outer), Zona fascitulata(middle), Zona reticularis(inner) Medulla |
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Definition
Major mineralcorticoid secreted by the adrenal cortex that maintains extra-cellular fluid volume |
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Term
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Definition
Produced by the adrenal cortex and are essential for life |
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Definition
Main glucocorticoid. Effects carb, protein, and fat metabolism; The body's response to stress; emotional stability; and immune function. |
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Definition
Androgens and estrogens. Secreted in low levels by the adrenal cortex in both genders. |
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Definition
Adrenal medullary hormones secreted due to stimulation of the sympathetic nervous system. Include epinephrine(85%) and norepinephrine(15%). |
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Term
Corticotropin-releasing hormone (CRH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. Stimulates ACTH synthesis, and secretion. |
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Term
Thyrotropin-releasing hormone (TRH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. Stimulates TSH and PRL secretion. |
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Term
Gonadotropin-releasing hormone (GnRH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. Stimulates FSH and LH secretion. |
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Term
Growth hormone-releasing hormone (GHRH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. Stimulates GH secretion. |
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Term
Growth hormone-inhibiting hormone (GHIH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. GH and GI hormone suppression. |
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Term
Prolactin-inhibiting hormone (PIH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. Inhibits PRL secretion. |
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Term
Melanocyte-inhibiting hormone (MIH) |
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Definition
Secreted by the hypothalamus, effects the anterior pituitary. Inhibits MSH secretion. |
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Definition
Thyroid hormone that affects the central and peripheral body systems. Increases basal metabolic rate, and regulates growth and development. |
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Term
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Definition
Thyroid hormone that affects the central and peripheral body systems. Increases basal metabolic rate, and regulates growth and development. |
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Definition
Thyroid hormone that affects the intestines, bones, and kidneys. Lowers blood calcium levels. |
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Parathyroid hormone (PTH) |
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Definition
Affects the bones, and kidneys. Increases blood calcium levels. |
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Term
Glucocorticoids (Cortisol) |
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Definition
Adrenal hormone that targets the liver. Stimulates gluconeogenesis. |
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Term
Mineralcorticoids (Aldosterone) |
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Definition
Adrenal hormone that targets the kidneys. Increases ion and water reabsorption |
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Definition
Ovarian hormone that targets cells throughout the whole body. Facilitates reproduction and sex characteristics. |
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Definition
Ovarian hormone that targets cells throughout the whole body. Facilitates reproduction and sex characteristics. |
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Definition
Testicular hormone that targets cells throughout the whole body. Facilitates reproduction and sex characteristics. |
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Definition
Pancreatic hormone that targets the liver, skeletal muscle, and fat tissue. Stimulates glucose absorption from the blood. |
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Definition
Pancreatic hormone that targets the liver. Stimulates glycogen to glucose conversion. |
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Term
Growth hormone-inhibiting hormone (GHIH, Somatostatin) |
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Definition
Targets the anterior pituitary and GI system. Causes GH and GI hormone suppression. |
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