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med surg final - DM drug therapy
drug therapy for DM - know MOA
25
Nursing
Graduate
03/17/2014

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Cards

Term
sulfonylureas
MOA
Definition
stimulate release of insulin from pancreatic islets; decrease glycogenosis and glyconeogenesis
enhance cellular sensitivity to insulin
Term
meglitinides
MOA
Definition
stimulate a rapid and short lived release of insulin from pancreas
Term
biguanide
MOA
Definition
decrease rate of hepatic glucose production; augments glucose uptake by tissues, especially muscles
Term
alpha-Glucosidase inhibitors
MOA
Definition
delay absorption of glucose from GI tract
Term
thiazolidinediones
MOA
Definition
increase glucose uptake in muscle; decrease endogenous glucose production
Term
dipeptidyl peptidase-4 (DDP-4) inhibitors
MOA
Definition
enhances the incretin system, stimulates release of insulin from pancreatic beta cells, and decreases hepatic glucose production
Term
combination therapy
glucovance
Definition
metformin and glyburide
Term
combination therapy
avandamet
Definition
rosiglitazone and metformin
Term
combination therapy
metaglip
Definition
metformin and glipizide
Term
combination therapy
duetact
Definition
pioglitazone and glimepiride
Term
combination therapy
actoplus met, actoplus met xr
Definition
metformin and pioglitazone
Term
combination therapy
janumet
Definition
metformin and sitagliptin
Term
combination therapy
prandimet
Definition
metformin and repaglinide
Term
combination therapy
avandaryl
Definition
rosiglitazone and glimepiride
Term
incretin mimetic
subq
MOA
Definition
stimulates release of insulin, decreases glucagon secretion, increases satiety, decreases gastric emptying
Term
amylin analog
subq
MOA
Definition
decreases gastric emptying, decreases glucagon secretion, decreases endogenous glucose output from liver, increase satiety
Term
sulfonylureas
drugs
Definition
glipizide
glyburide
glimepiride
Term
meglitinides
drugs
Definition
repaglinide
nateglinide
Term
biguanide
drugs
Definition
metformin
Term
alpha-Glucosidase inhibitors
drugs
Definition
acarbose
Term
thiazolidinediones
drugs
Definition
pioglitazone
rosiglitazone
Term
dipeptidyl peptidase-4 (DDP-4) inhibitors
drugs
Definition
sitagliptin (Januvia)
saxagliptin
Term
incretin mimetic
drugs
Definition
exenatide
liraglutide
Term
amylin analog
drugs
Definition
pramlintide
Term
combination therapy
MOA
Definition
refer to individual MOA
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