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Med Surg: Endocrine - Diseases (Test 1)
Winter Semester - 2011
54
Medical
Graduate
01/17/2011

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Cards

Term
Which condition has characteristic test result of elevated (fasting AM) PRL?
Definition
Hyperprolactinemia
Term
What is the MC type of pituitary adenoma?
Definition
Lactotroph
Term
Which section of the adrenal cortex secretes the mineralcorticoid, aldosterone?
Definition
Zona glomerulosa
Term
Which section of the adrenal cortex secretes the glucocorticoid, cortisol?
Definition
Zona Fasiculata
Term
Which section of the adrenal cortex secretes the gonadocorticoids?
Definition
Zona Reticularis
Term
What does the somatotroph type of pituitary adenoma secrete?
Definition
Secretes GH
Term
What does the lactotroph type of pituitary adenoma secrete?
Definition
PRL
Term
What does the corticotroph type of pituitary adenoma secrete?
Definition
ACTH
Term
What does the gonadotroph type of pituitary adenoma secrete?
Definition
FSH/LH
Term
What does the thyrotroph type of pituitary adenoma secrete?
Definition
TSH
Term
If a female presents with oligomenorrhea, galactorrhea and infertility what condition should you suspect?
Definition
Hyperprolactinemia
Term
If a male presents with hypogonadism, decreased libido, ED, infertility, what condition should you suspect?
Definition
Hyperprolactinemia
Term
What effect can hyperprolactinemia have on the bones, if left untreated?
Definition
Osteoporosis/Osteopenia and Pathologic Fx
Term
What are some pharmocologic causes of hyperprolactinemia?
Definition
Ranitidine (Zantac)
Amphetimines
Cimetidine (Tagamet)
Estrogens
Opioids
Nicotine
Verapamil
Cocaine
Marijuana - causes galactorrhea
Term
Which condition is described as a loss of one or more hormones of the anterior pituitary?
Definition
Hypopituitarism
Term
What is the loss of ALL anterior pituitary hormones called?
Definition
Panhypopituitarism
Term
If a pt presents with abnormal height (short stature), short neck, trunk and limb length, and difficulties hearing, what condition might you suspect?
Definition
Dwarfism
Term
If a patient presents with soft, doughy hands, hyperhydrosis, and excessive growth of hands and feet, what condition should you suspect?
Definition
Acromegaly
Term
If a patient presents with an abnormally tall height for their genetic make-up, LV involvement, amenorrheic and with hyperhydrosis, what condition should you suspect?
Definition
Gigantism
Term
If a pt presents with psychological changes, muscle wasting, thin skin, hyperglycemia, and central obesity, what condition should be suspected?
Definition
Cushing's
Term
What condition is described by excess secretion of ACTH from the anterior pituitary?
Definition
Cushing's Disease
Term
What condition is characterized by excess secretion of cortisol and normal levels of ACTH?
Definition
Cushing's syndrome
Term
What condition is characterized by hyper-secretion of ACTH and the appearance of a pituitary adenoma following a bilateral adrenalectomy for Cushing's?
Definition
Nelson's Disease
Term
If a patient complains of hyperpigmentation, HA, and visual changes post-op for bilateral adrenalectomy, what condition is suspected?
Definition
Nelson's Dx
Term
Which two drugs can lead to the development of DI?
Definition
Lithium and Corticosteroid Use
Term
If a pt presents with dehydration, hypernatremia, nocturia, polyuria, and polydipsia, what condition should you suspect?
Definition
DI
Term
What condition is characterized by ADH deficiency?
Definition
Central DI
Term
What amount is considered polyuria?
Definition
2 - 20L/d (hypotonic appearance)
Term
If a pt presents with CVA tenderness, HTN, constipation, mental changes, bone aches and fatigue, what condition should you suspect?
Definition
Hyperparathyroidism
Term
If a patient's labs have elevated ACTH and cortisol levels, what condition should you suspect? What tests should be done to confirm diagnosis?
Definition
Cushing's disease
Desmopressin Suppression test
Term
If on a pts x-rays a "rugger jersey" spine or "salt and peppering" of the skull are noted, along with complaints of bone pain, fatigue, and N/V, what condition should you suspect?
Definition
Hyperparathyroidism
Term
If a pts serum PTH, Ca, & Alk Phos are elevated along with elevated urine Ca and PO4, what condition should you suspect?
Definition
Hyperparathyroidism
Term
If on EKG a pt has shortened QT interval, prolonged PR, and complains of HTN, numerous infections, polyuria, polydipsia, Anorexia and weight loss, what condition should you suspect?
Definition
Hyperparathyroidism
Term
In which condition are Chvostek's and Trousseau's phenomenon characteristic indicators?
Definition
Hypoparathyroidism
Term
If a pt presents with low urine Ca excretion, high serum PO4, low serum Mg, low serum Ca, and Alk Phos WNL, what condition would you expect?
Definition
Hypoparathyroidism
Term
If a pt presents with muscle cramps, tetany, abdominal cramps, and tingling of the feet, lips and hands, what condition should you suspect?
Definition
Hypoparathyroidism
Term
Which condition has signs and symptoms including loss of eyebrow hair, cutaneous calcifications, cataracts, dry and scaly skin, brittle nails, irritability and anxious state?
Definition
Hypoparathyroidism
Term
If a pt has an irregular EKG showing prolonged QT intervals with T-wave abnormalities, as well as x-rays showing increased bone density and cutaneous calcifications, what condition should be suspected?
Definition
Hypoparathyroidism
Term
What is the MC cause of hyperthyroidism?
Definition
Grave's Disease
Term
What is the MC cause of thyroiditis?
Definition
Hashimoto's
Term
What are the markers for Grave' s Disease?
Definition
TSH-R Ab (TR-Ab)
Term
What are the markers for Hashimoto's?
Definition
Thyroperoxidase or Thyroglobin Anti-bodies (TPO)
Term
What are patients who have Hasimoto's at a greater risk for developing?
Definition
Papillary Thyroid CA
Term
What diseases are Grave's disease associated with?
Definition
Myasthenia Gravis, pernicious anemia and DM
Term
If a pt presents with an asymmetrically enlarged goiter, mild xerostomia (dry mouth) and dry eyes, with bouts of palpitations, anxiety and sweating, what condition should you suspect?
Definition
Hashimoto's
Term
What condition presents with very high fever, marked delirium, severe tachycardia, dehydration and V/D?
Definition
Thyroid Storm
Term
If a pt presents with hoarseness, macroglossia, bradycardia, an enlarged heart, weight gain, constipation, decreased memory and hearing, paresthesias, cold intolerance menorrhagia, and hyporeflexia, what condition should you suspect?
Definition
Hypothyroidism
Term
If TSH levels are high, but T4 levels are low, what condition should you suspect?
Definition
Hypothyroidism
Term
What condition occurs in post-partum women, especially when there is large volumes of blood loss during pregnancy?
Definition
Sheehan's syndrome
Term
If a post-partum pt complains of inability to breast feed, has weight gain, cold intolerance, dry skin, hypotension, amenorrheic, what condition should you suspect?
Definition
Sheehan's Syndrome
Term
What test is MANDATORY following the finding of a single or multiple thyroid nodules?
Definition
Thyroid Function Test
Term
If a pt presents with makedly high ACTH (>200pg/mL), low cortisol levels, and serum K and BUN high, what condition should you suspect?
Definition
Acute AI
Term
If a pt presents with a high fever, N/V/D, Lasitude, Abdominal pain, confusion, coma, HA, and Low BP, what condition should you suspect?
Definition
Acute AI
Term
What condition is characterized by excess secretion of cortisol due to a tumor in the adrenal glands?
Definition
Primary AI (Conn's Dx)
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