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Pharm -- Pulm
First Aid 2012 pp575-577
31
Medical
Graduate
02/05/2013

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Cards

Term
diphenhydramine
Definition
first generation
reversible H1 inhibitors (more CNS effects)
Term
dimenhydrinate
Definition
first generation
reversible H1 inhibitors (more CNS effects)
Term
chlorpheniramine
Definition
first generation
reversible H1 inhibitors (more CNS effects)
Term
loratidine
Definition
second generation
reversible H1 inhibitors (less CNS effects)
Term
fexofenadine
Definition
second generation
reversible H1 inhibitors (less CNS effects)
Term
desloratadine
Definition
second generation
reversible H1 inhibitors (less CNS effects)
Term
cetirizine
Definition
second generation
reversible H1 inhibitors (less CNS effects)
Term
promethazine
Definition
first generation
reversible H1 inhibitors (more CNS effects)
for anti-emetic
Term
meclizine
Definition
first generation
reversible H1 inhibitors (more CNS effects)
for vertigo, motion sickness
Term
hydroxyzine
Definition
first generation
reversible H1 inhibitors (more CNS effects)
Term
doxylamine
Definition
first generation
reversible H1 inhibitors (more CNS effects)
Term
salmeterol
Definition
long-acting beta2 agonist
Term
theophylline
Definition
methylxanthines; inhibits phosphodiesterase --> increase cAMP
Term
ipratropium
Definition
competitively blocks muscarinic receptor
Term
beclomethasone
Definition
inhaled corticosteroids (inhibits synthesis of cytokines, inactivates NF-kB, etc.)
Term
fluticasone
Definition
inhaled corticosteroids (inhibits synthesis of cytokines, inactivates NF-kB, etc.)
Term
flunisolide
Definition
inhaled corticosteroids (inhibits synthesis of cytokines, inactivates NF-kB, etc.)
Term
zileuton
Definition
5-lipoxygenase pathway inhibitor (prevents formation of leukotrienes)
Term
zafirlukast
Definition
blocks leukotriene receptor
Term
montelukast
Definition
blocks leukotriene receptor
Term
guaifenesin (what is it, not the mechanism)
Definition
expectorant, does NOT suppress cough
Term
N-acetylysteine
Definition
cleaves disulfide bonds in mucus glycoproteins --> loosen mucus plugs (mucolytic)
Term
bosentan
Definition
blocks endothelin-1 (vasoconstrictor) receptors (used for pulm HTN)
Term
dextromethorphan
Definition
blocks NMDA glutamate receptors (anti-tussive)
Term
pseudoephedrine
Definition
alpha-agnoist
Term
methacholine
Definition
muscarinic receptor agnoist
Term
what does theophylline block the action of
Definition
adenosine!!
Term
cromolyn
Definition
prevents mast cell mediator release
Term
theophylline side effects
Definition
cardiotoxicity --> tachyarrhythmias, neurotoxicity --> seizures!!
Term
zafirlukast, montelukast especially good for...
Definition
aspirin-induced asthma
Term
too much nasal decongestants
Definition
>= 3 days --> decreased NE prod --> rebound rhinnorhea (congestion +/- rhinorrhea)
tx: stop med, allow NE to recover
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