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MdDx exam 4
Sinnots final gift
68
Medical
Graduate
12/10/2013

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Cards

Term
How many L of blood in body? how much is plasma? how much is cells?
Definition
5 L total
3 L plasma
2 L cells
Term
what is the other name of WBC? what is their primary purpose?
Definition
leukocytes. act to phagocytosis
Term
life span of WBC
Definition
13-20 days
Term
what are normal WBC count for infants/adult males/ adult females
Definition
infants = 9000 to 30,000
adults = 5000 - 10,000
Term
what WBC and neutrophil values indicate immunosuppression?
Definition
wbc = <1000
neutrophils = <500
Term
how many wbc (leukocyte count) when leukocytosis is an issue?
Definition
>10,000
Term
what WBC count indicative of leukopenia?
Definition
<4,000
Term
what WBC counts are indicative of "CLINICAL ALERT"?
Definition
<500 and >30,000
PANIC!!!
Term
what are dietary/pharmacologic no-no's for someone with leukopenia?
Definition
no fresh fruit/veggies
no NSAIDS
Term
what a re neutrophilia and neutropenia levels? (#)
Definition
neutrophilia is >8000
neutropenia is < 1800
Term
what is the normal number of lymphocytes?
Definition
1500-4000 cells/mm3
Term
lymphocytosis values in adults and children?
Definition
adults = >4000
children = >7200
Term
lymphopenia in adults/children (#s)
Definition
adults = <1000
children = <2500
Term
RBC count, Hgb count, and HCT count in men vs women
Definition
RBC: men = 4.7-6.1; women = 4.2-5.4
Hgb: men = 14-18; women = 12-16
HCT: men = 42-52; women = 37-47
Term
what is hematocrit?
Definition
% volume of RBC in packed cell volume (PCV)

significant in anemia and polycythemia
Term
what happens with incr HCT? and what % value indicates spontaneous bleeding?
Definition
erythrocytosis, shock with hemoconcentration.

hct > 60% --> spontaneous clotting of blood
Term
what happens with decreased Hct?
Definition
leukemia, anemia

hct<20% --> cardiac failure/death
Term
importance of hemoglobin?

what ml of O2 value?
Definition
oxygen carrying capacity of blood is directly related to Hgb

1.34 ml of o2/gram of Hgb
Term
what is CaO2? normal values?
Definition
oxygen carrying capacity of blood

normal values = 16-22 ml O2/dl of blood
benchmark is 20
Term
what is normal PaO2?
Definition
80-100 mmHg
Term
what Hgb count is indicative of heart failure and death?
Definition
<5 g/dL
Term
what can happen with increased hgb? (>20gm/dL)
Definition
capillary clotting
Term
what value of platelets is indicative of thrombocythemia? clinical symptoms?
Definition
>1000 platelets

epistaxis, GI bleed, bleeding gums
Term
what is normal time for activated partial thromboplastin time? (APTT)
Definition
21-35 seconds
Term
what is a poor time for ATPP and what are the consequences?
Definition
>100 seconds
spontaneous bleeding
Term
if person is on heparin, what are the normal values for ATPP?
Definition
2-2,5 times the normal value, so
50-88 seconds
Term
what is normal prothrombin time? (PT)
Definition
11-13 seconds
Term
at what INR should you notify physician?
Definition
INR>4
Term
where is HDL formed? what does it do?
how does it increasE? normal values?
Definition
HDL formed in liver, carries excess cholesterol back to liver for removal (about 25%)
INCREASES WITH EXERCISE, MODERATE etoh, AND INSUIN
>60 ideal, > no risk, <35 high risk
Term
LDLs (values and risk)
Definition
high risk >160
low risk < 130
*carries 75% of cholesterol away from liver to other areas like arterial walls
Term
ideal triglyceride values
Definition
<140
Term
LDL:HDL ratio
Definition
used to determine cardiac risk

low risk <3.0
high risk >6
Term
cholesterol:HDL ratio
Definition
low risk 3.3-4.4
high risk >11
Term
what CK % in myocardium (CK MB) correlates with MI?
Definition
>5% CK MB correlates with MI
Term
what enzyme should you be aware of for an acute MI?
Definition
troponin. normal value is 0.2 ug/mL
as a clinician, request two tropinin level tets. if both abnormal, request permission to work with patient
Term
wht diseases are associated with HLA?
Definition
MS, AS, MG, graves, JRA, polymyalgia rheumatica (effectively treated with tapering dose of steroids)
Term
normal urine volume in 24 hours
criteria for oliguria
Definition
normal = 600-2500 ml/24 hrs

oliguria = <200 ml/24 hr
Term
name a contraindication after thoracentesis
Definition
no manual therapy
Term
ERV
Definition
expiratory reserve volume
measure of max exertion
normal 1000 mL
reduced in restrictive disease
Term
VC
Definition
vital capacity
normal is 4-6 L
80% of total lung capacity
decr in both obstructive and restrictive dx
Term
what are normal/abnormal FEV1 values?
Definition
no obstruction = > 2 L
mild to mod obstruction = 1-2 L
severe obstruction = <1 L
Term
FEV1 %

what is normal FEV1 / FVC?
Definition
>75%
restrictive = >80-90%
obstructive = <70%
Term
ABCs (arterial blood gases)
what can theymeasure?
Definition
ventilation
O2 transport
acid-base data
Term
what are normal ABGs
Definition
pH=7.35-7.45
PaCO2= 35-45 mmHg
PaO2= 80-100 mmHg
HCO3= 22-26 mEq/L
O2 sat= 95-100%
Term
critical values for ABGs
Definition
pH < 7.25 or >7.55
PaCO2 <20 or >60
PaO2 < 40 mmHg
HCO3 < 15 or >40 mEq/L
O2 sat < 90%
Term
why is Iron important? how is absorption regulated?
Definition
Irons role in metabolism is to produce hemoglobin
absorption is regulated by the protein transerrin, which is synthesized in the liver
Term
what is ferritin?
Definition
a major iron storage protein
most reliable indicator of total body iron stores
Term
why is vit B12 important and where does it comr from
what are normal adult values?
Definition
B12 needed for RBC production. comes from animal protein

normal adult values = 100-700 pg/ml
Term
normal folic acid (folate)
Definition
2-20 mg/ml
Term
K+ values (infant, child, adult)
Definition
infant = 4-5
child = 3.5-4.5
adult = 3.5-5
Term
Na+ values infant child adult
Definition
infant = 134-150
child = 136-145
afdult = 136-145
Term
Cl- values infant/child/adult
Definition
all three = 90-100
Term
Ca2+ values infant, child, adult
Definition
all three = 8.89-10.8
Term
Ca2+ alerts
Definition
<6 mg/dl --> tetany and convulsions
>13 --> cardiotoxicity and arrhythmias and coma

50% of calcium is protein bound and 50% is ionized at any given time (bound to albumin)
Term
what is the chief base of the blood
Definition
Na+
Term
most succeptible organ to Na+ changes?
Definition
brain
Term
normal values for Na+?
Definition
136-145
Term
Na+ panic
Definition
<120 = weakness
90-95 = neurologic sxs
> 155 --> cardio and renal sxs
>160 --> heart failure
Term
normal K+ levels
Definition
3.5-5
Term
most succeptible organ for K+?
Definition
heart
Term
most succeptible organ for K+?
Definition
heart
Term
what levels of K+ is therapy contraindicated?

medical emergency?
Definition
<3.2 and > 5.1

<2.8 or > 6.2
Term
where are Na and K located cellulary-wise?
Definition
K+ is intracellular
Na+ is extracellular
Term
what is normal fasting glucose? upper limit?
what is considered low BG and why dangerous?
Definition
normal is 80-90 mg/dl
upper limit is 110
low is <20-50 (hypoglycemic shock)
Term
what is pre-diabtetes level?
Definition
fasting glucose of 100-125
or OGTT of 140-200 mg/dL
Term
what is primary organ of glucose balance
Definition
liver
Term
ADA recommendations fo HbA1C
Definition
if >8%, action taken
DM under control if <7%
each 1% in HbA1C = 30 mg/dl change in glucose
Term
exercise considerations for someone with neuropathy
Definition
avoid increase in SBP > 30 mmHg above rest, no valsalva, keep SBP total <180 mmHg, keep RT to <70 % 1RM and HR <85% HRmax
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